Anti-Human FHL1 Polyclonal Antibody

Catalog No.

PHG62701

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human FHL1 (Met1-Lys220).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

SLIM, SLIM1, Four and a half LIM domains protein 1, FHL-1, SLIM-1, Skeletal muscle LIM-protein 1, FHL1

Purification

Purified by antigen affinity column.

Accession

Q13642

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

The 4 functional segments of Factor H: Role in physiological target recognition and contribution to disease., PMID:40356067

Autoantibodies Against Factor B and Factor H Without Pathogenic Effects in a Patient with Immune Complex-Mediated Membranoproliferative Glomerulonephritis., PMID:40149624

Common Haplotypes within the Chromosome 1q31.3 Region Determine Systemic Concentrations of the Entire Complement Factor H Protein Family., PMID:40139172

Pathogenic mechanisms of disease in idiopathic inflammatory myopathies: autoantibodies as clues., PMID:39281689

Anti-FHL1 autoantibodies in adult patients with myositis: a longitudinal follow-up analysis., PMID:38833674

Anti-FHL1 autoantibodies in juvenile myositis are associated with anti-Ro52 autoantibodies but not with severe disease features., PMID:35961028

An Interdisciplinary Diagnostic Approach to Guide Therapy in C3 Glomerulopathy., PMID:35693785

Anti-FHL1 antibody: welcome to a novel autoantibody in myositis., PMID:35460231

Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338

Autoantibodies against four-and-a-half-LIM domain 1 (FHL1) in inflammatory myopathies: results from an Australian single-centre cohort., PMID:35022656

FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress., PMID:34239032

Targeted Luminescent Probes for Precise Upconversion/NIR II Luminescence Diagnosis of Lung Adenocarcinoma., PMID:33705098

A Dominant C150Y Mutation in FHL1 Induces Structural Alterations in LIM2 Domain Causing Protein Aggregation In Human and Drosophila Indirect Flight Muscles., PMID:33515430

Targeting the complement system in neuromyelitis optica spectrum disorder., PMID:33513036

MiR-96-5p Induced by Palmitic Acid Suppresses the Myogenic Differentiation of C2C12 Myoblasts by Targeting FHL1., PMID:33322515

Concurrent positive anti-3-hydroxy-3-methylglutaryl-coenzyme a reductase antibody with reducing body myopathy: Possible double trouble., PMID:31204143

Beef tenderness and intramuscular fat proteomic biomarkers: Effect of gender and rearing practices., PMID:30894324

FHL1B Interacts with Lamin A/C and Emerin at the Nuclear Lamina and is Misregulated in Emery-Dreifuss Muscular Dystrophy., PMID:27911330

Inflammatory myopathies: Anti-FHL1 antibodies linked to IIM., PMID:26607388

Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies., PMID:26551678

The Plasmodium falciparum blood stages acquire factor H family proteins to evade destruction by human complement., PMID:26457721

Dynamic expression of molecules that control limb muscle development including Fhl1 in hind limbs of different gestational age., PMID:24475781

The four and a half LIM family members are novel interactants of the human T-cell leukemia virus type 1 Tax oncoprotein., PMID:23616667

Evaluation of protein expression pattern of stanniocalcin 2, insulin-like growth factor-binding protein 7, inhibin beta A and four and a half LIM domains 1 in esophageal squamous cell carcinoma., PMID:23321464

Leptospiral immunoglobulin-like proteins interact with human complement regulators factor H, FHL-1, FHR-1, and C4BP., PMID:22291192

A novel monoclonal antibody against FbaA can inhibit the binding of the complement regulatory protein factor H to group A streptococcus., PMID:21228138

Secreted Aspergillus fumigatus protease Alp1 degrades human complement proteins C3, C4, and C5., PMID:20498262

FHL1 interacts with oestrogen receptors and regulates breast cancer cell growth., PMID:19840196

Mutations of the FHL1 gene cause Emery-Dreifuss muscular dystrophy., PMID:19716112

HOXD13 may play a role in idiopathic congenital clubfoot by regulating the expression of FHL1., PMID:18758158

Immunological and molecular analyses of the Borrelia hermsii factor H and factor H-like protein 1 binding protein, FhbA: demonstration of its utility as a diagnostic marker and epidemiological tool for tick-borne relapsing fever., PMID:16861638

Ascitic complement system in ovarian cancer., PMID:15726105

Immune evasion of the Lyme disease spirochetes., PMID:15569625

The hyphal and yeast forms of Candida albicans bind the complement regulator C4b-binding protein., PMID:15501796

Expression of complement factor H by lung cancer cells: effects on the activation of the alternative pathway of complement., PMID:15342420

Glomerular deposition and urinary excretion of complement factor H in idiopathic membranous nephropathy., PMID:15331938

Immunological characterization of the complement regulator factor H-binding CRASP and Erp proteins of Borrelia burgdorferi., PMID:15146998

Skeletal muscle LIM protein 1 (SLIM1/FHL1) induces alpha 5 beta 1-integrin-dependent myocyte elongation., PMID:12917103

[LIM protein KyoT2 interacts with human tight junction protein ZO-2-i3]., PMID:12645256

Secretion of soluble complement inhibitors factor H and factor H-like protein (FHL-1) by ovarian tumour cells., PMID:12402151

[Screening and detecting of proteins interaction with KyoT]., PMID:11902002

Characterization of tissue-specific LIM domain protein (FHL1C) which is an alternatively spliced isoform of a human LIM-only protein (FHL1)., PMID:11400158

Complement evasion by Borrelia burgdorferi: serum-resistant strains promote C3b inactivation., PMID:11349031

The cardiac expression of striated muscle LIM protein 1 (SLIM1) is restricted to the outflow tract of the developing heart., PMID:10329211

The influence of different isolation procedures and the use of target cells from melanoma cell lines and short-term cultures on the non-specific cytotoxic effects of lymphocytes from healthy donors., PMID:1056313

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