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Anti-Human MYH11 Polyclonal Antibody

Catalog #:   PHE15401 Specific References (28) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P35749
Overview

Catalog No.

PHE15401

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human MYH11 (Met1-Asp406).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

KIAA0866, SMMHC, MYH11, Myosin heavy chain 11, Myosin-11, Myosin heavy chain, smooth muscle isoform

Purification

Purified by antigen affinity column.

Accession

P35749

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN-BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with MYH11 antibody (PHE15401) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 48 kDa
    Observed MW: 48 kDa
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with MYH11 antibody (PHE15401) at 1 μg/ml.

    Lane 1: Mouse muscle

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 227 kDa
    Observed MW: 227 kDa
  • Immunohistochemical
    Immunohistochemical analysis of mouse lung stained for MYH11 with PHE15401.
References

Single-cell transcriptome analysis reveals CD34 as a marker of human sinoatrial node pacemaker cardiomyocytes., PMID:39604360

A novel co-culture assay to evaluate the effects of sympathetic innervation on vascular smooth muscle differentiation., PMID:36731293

Histopathological, Ultrastructural, and Immunohistochemical Findings in MYH11-Variant Visceral Myopathy., PMID:36571289

Identification of immune cell infiltration and diagnostic biomarkers in unstable atherosclerotic plaques by integrated bioinformatics analysis and machine learning., PMID:36211422

Emerging therapies for inv(16) AML., PMID:33821975

Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models., PMID:33082445

New Insights into the Pathophysiology of Primary and Secondary Lymphedema: Histopathological Studies on Human Lymphatic Collecting Vessels., PMID:32716244

Clinical and immunological features of platelet transfusion refractoriness in young patients with de novo acute myeloid leukemia., PMID:32419364

The Incidence and Immunophenotypic and Genetic Features of JL1 Expressing Cells and the Therapeutic Potential of an Anti-JL1 Antibody in De Novo Pediatric Acute Leukemias., PMID:30809981

Liraglutide inhibited AGEs induced coronary smooth muscle cell phenotypic transition through inhibiting the NF-κB signal pathway., PMID:30513352

Resident cell lineages are preserved in pulmonary vascular remodeling., PMID:29359814

Distinct molecular subtypes of uterine leiomyosarcoma respond differently to chemotherapy treatment., PMID:28893210

[Successful high-dose dexamethasone treatment of acquired pure red cell aplasia following ABO major mismatched allogeneic hematopoietic stem cell transplantation]., PMID:27384857

Myoepithelial cells in lobular carcinoma in situ: distribution and immunophenotype., PMID:27195907

LRIG1 Regulates Ontogeny of Smooth Muscle-Derived Subsets of Interstitial Cells of Cajal in Mice., PMID:25921371

Detection of fusion genes at the protein level in leukemia patients via the flow cytometric immunobead assay., PMID:21123134

[Study on proteomic specificity of unstable angina with qi deficiency and blood stasis syndrome]., PMID:19702077

Myeloid sarcoma of the small bowel associated with a CBFbeta/MYH11 fusion and inv(16)(p13q22): a case report., PMID:19638550

Identification and characterization of Myosin from rat testicular peritubular myoid cells., PMID:18716291

Lymphoplasmacytic lymphoma/Waldenström macroglobulinemia with inv(16)(p13q22) as a sole genetic abnormality., PMID:17452259

Immunohistochemical analysis of CBFbeta-SMMHC protein reveals a unique nuclear localization in acute myeloid leukemia with inv(16)(p13q22)., PMID:17063086

Comparative study of expressions of cytoplasmic CD79a and other B-lymphoid immunomarkers in acute leukemic cells., PMID:16403258

An inv(16)(p13q22) positive acute myeloid leukaemia relapsing as acute precursor B-cell lymphoblastic leukaemia., PMID:15339697

The PEBP2beta/CBF beta-SMMHC chimeric protein is localized both in the cell membrane and nuclear subfractions of leukemic cells carrying chromosomal inversion 16., PMID:10914550

Minimally differentiated acute myeloid leukemia (AML M0): clinico-biological findings of 29 cases., PMID:10721774

The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates., PMID:9819429

Characterization and use of an antibody detecting the CBFbeta-SMMHC fusion protein in inv(16)/t(16;16)-associated acute myeloid leukemias., PMID:9490670

Identification of the chimeric protein product of the CBFB-MYH11 fusion gene in inv(16) leukemia cells., PMID:8818654

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human MYH11 Polyclonal Antibody [PHE15401]
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