Catalog No.
PHA88101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ZEB2 (Ser647-Ser705).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Smad-interacting protein 1, SIP1, SMADIP1, ZFX1B, KIAA0569, ZEB2, Zinc finger E-box-binding homeobox 2, ZFHX1B, Zinc finger homeobox protein 1b
Purification
Purified by antigen affinity column.
Accession
O60315
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Jieduquyuziyin prescription suppresses the activation of the extrafollicular effector B cell by regulating integrin αV signaling in systemic lupus erythematosus., PMID:40318773
Identifying hub genes in response to ustekinumab and the impact of ustekinumab treatment on fibrosis in Crohn's disease., PMID:38840917
The ETV6-MECOM fusion protein promotes EMT-related properties by repressing the transactivation activity of E-cadherin promoter in K562 leukemia cells., PMID:38405662
The lncRNA expression profile signature of leukemia stem cells is altered upon PI3K/mTOR inhibition: an in vitro and in silico study., PMID:37470414
Plasma and Peritoneal Fluid ZEB Levels in Patients with Endometriosis and Infertility., PMID:36289723
Pirfenidone mitigates TGF-β1-mediated fibrosis in an idiopathic inflammatory myositis-associated interstitial lung disease model., PMID:35504143
ZEB2 facilitates peritoneal metastasis by regulating the invasiveness and tumorigenesis of cancer stem-like cells in high-grade serous ovarian cancers., PMID:34211089
The Role of ZEB2 in Human CD8 T Lymphocytes: Clinical and Cellular Immune Profiling in Mowat-Wilson Syndrome., PMID:34070208
Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia., PMID:33400146
Molecular phenotypes of circulating tumor cells and efficacy of nivolumab treatment in patients with head and neck squamous cell carcinoma., PMID:33299117
Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses., PMID:32826341
Wnt signaling and Loxl2 promote aggressive osteosarcoma., PMID:32686768
[Morphological and immunohistochemical characteristics of the molecular subtypes of urothelial carcinomas]., PMID:31626203
Role of epithelial-mesenchymal transition factors in the histogenesis of uterine carcinomas., PMID:30739164
The effect of gap junction-mediated transfer of miR-200b on osteogenesis and angiogenesis in a co-culture of MSCs and HUVECs., PMID:29898921
Genome-wide analysis of endogenously expressed ZEB2 binding sites reveals inverse correlations between ZEB2 and GalNAc-transferase GALNT3 in human tumors., PMID:29516288
miR-200c inhibits TGF-β-induced-EMT to restore trastuzumab sensitivity by targeting ZEB1 and ZEB2 in gastric cancer., PMID:29302045
Mesenchymal stem cells in inflammatory microenvironment potently promote metastatic growth of cholangiocarcinoma via activating Akt/NF-κB signaling by paracrine CCL5., PMID:29088737
Expression of Epithelial-Mesenchymal Transition Regulating Transcription Factors in Head and Neck Squamous Cell Carcinomas., PMID:28982853
GSK3 Inhibition Drives Maturation of NK Cells and Enhances Their Antitumor Activity., PMID:28790065
ZEB1-regulated inflammatory phenotype in breast cancer cells., PMID:28618162
Topics in histopathology of sweat gland and sebaceous neoplasms., PMID:28256768
Bonafide Targets of Deregulated microRNAs in Non-Small Cell Lung Cancer as Tool to Identify Novel Therapeutic Targets: A Review., PMID:27719642
EphrinB2 repression through ZEB2 mediates tumour invasion and anti-angiogenic resistance., PMID:27470974
Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals., PMID:27385012
MicroRNA-145 inhibits hepatic stellate cell activation and proliferation by targeting ZEB2 through Wnt/β-catenin pathway., PMID:27289031
Long non-coding RNA urothelial cancer-associated 1 promotes bladder cancer cell migration and invasion by way of the hsa-miR-145-ZEB1/2-FSCN1 pathway., PMID:26544536
MicroRNA signature characterizes primary tumors that metastasize in an esophageal adenocarcinoma rat model., PMID:25826212
ZEB2 promotes vasculogenic mimicry by TGF-β1 induced epithelial-to-mesenchymal transition in hepatocellular carcinoma., PMID:25818166
Silencing of COX-2 by RNAi modulates epithelial-mesenchymal transition in breast cancer cells partially dependent on the PGE2 cascade., PMID:25520137
ZEB2 and ZEB1 expression in a spontaneous canine model of invasive micropapillary carcinoma of the mammary gland., PMID:25447746
Overexpression of SATB1 is associated with biologic behavior in human renal cell carcinoma., PMID:24835085
Androgen receptor as a regulator of ZEB2 expression and its implications in epithelial-to-mesenchymal transition in prostate cancer., PMID:24812058
A multimarker panel for circulating tumor cells detection predicts patient outcome and therapy response in metastatic colorectal cancer., PMID:24752533
β1 integrin inhibition elicits a prometastatic switch through the TGFβ-miR-200-ZEB network in E-cadherin-positive triple-negative breast cancer., PMID:24518294
ZEB2-Sp1 cooperation induces invasion by upregulating cadherin-11 and integrin α5 expression., PMID:24130169
Epithelial-mesenchymal transition markers expressed in circulating tumor cells in hepatocellular carcinoma patients with different stages of disease., PMID:24091674
Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer., PMID:23576557
Olfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heart., PMID:23264563
MiR-145 regulates epithelial to mesenchymal transition of breast cancer cells by targeting Oct4., PMID:23049906
Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification., PMID:22833130
ZEB2 mediates multiple pathways regulating cell proliferation, migration, invasion, and apoptosis in glioma., PMID:22761708
ZEB2 upregulates integrin α5 expression through cooperation with Sp1 to induce invasion during epithelial-mesenchymal transition of human cancer cells., PMID:22227038
Change in microRNAs associated with neuronal adaptive responses in the nucleus accumbens under neuropathic pain., PMID:22031875
miR-200b precursor can ameliorate renal tubulointerstitial fibrosis., PMID:21049046
Novel monoclonal antibodies detect Smad-interacting protein 1 (SIP1) in the cytoplasm of human cells from multiple tumor tissue arrays., PMID:20515682
Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors., PMID:20424117
Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer., PMID:19502595
TMPRSS4 promotes invasion, migration and metastasis of human tumor cells by facilitating an epithelial-mesenchymal transition., PMID:17968309
Snail-dependent and -independent epithelial-mesenchymal transition in oral squamous carcinoma cells., PMID:16899764
For research use only. Not for human or drug use.
