Catalog No.
PHB39201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human WFS1 (Arg653-Ser869).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
WFS1, Wolframin
Purification
Purified by antigen affinity column.
Accession
O76024
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Identification of a pathogenic founder variant in the WFS1 gene that causes Wolfram syndrome in the Druze population., PMID:39944315
Molecular and clinical profiles of pediatric monogenic diabetes subtypes: comprehensive genetic analysis of 138 patients., PMID:39504571
RNASeq highlights ATF6 pathway regulators for CHO cell engineering with different impacts of ATF6β and WFS1 knockdown on fed-batch production of IgG1., PMID:38898154
Identification of hippocampal area CA2 in hamster and vole brain., PMID:38405991
High Frequency of Recessive WFS1 Mutations Among Indian Children With Islet Antibody-negative Type 1 Diabetes., PMID:37931151
Identification of monogenic variants in more than ten per cent of children without type 1 diabetes-related autoantibodies at diagnosis in the Finnish Pediatric Diabetes Register., PMID:36418577
Comprehensive genetic screening reveals wide spectrum of genetic variants in monogenic forms of diabetes among Pakistani population., PMID:34888019
A Novel Genetic Variant in the WFS1 Gene in a Patient with Partial Uniparental Mero-Isodisomy of Chromosome 4., PMID:34360843
Searching for Monogenic Diabetes in a High-risk Autoimmune Diabetes Cohort: Needles in a Paperclip Stack., PMID:33860317
Monogenic Causes in the Type 1 Diabetes Genetics Consortium Cohort: Low Genetic Risk for Autoimmunity in Case Selection., PMID:33538814
Efficacy of GLP-1 Agonist Therapy in Autosomal Dominant WFS1-Related Disorder: A Case Report., PMID:33075784
Type 1 diabetes genetic risk score discriminates between monogenic and Type 1 diabetes in children diagnosed at the age of <5 years in the Iranian population., PMID:31276222
COL4A3 Gene Variants and Diabetic Kidney Disease in MODY., PMID:30012629
Clinical Characteristics of Wolfram Syndrome in Chinese Population and a Novel Frameshift Mutation in WFS1., PMID:29483894
Complex multi-block analysis identifies new immunologic and genetic disease progression patterns associated with the residual β-cell function 1 year after diagnosis of type 1 diabetes., PMID:23755131
Localization and distribution of wolframin in human tissues., PMID:22202014
Expression and localization of Wolfram syndrome 1 gene in the developing rat pancreas., PMID:19916172
Expression of the diabetes risk gene wolframin (WFS1) in the human retina., PMID:19523951
WFS1 mutations are frequent monogenic causes of juvenile-onset diabetes mellitus in Lebanon., PMID:18806274
Wolfram syndrome 1 (WFS1) protein expression in retinal ganglion cells and optic nerve glia of the cynomolgus monkey., PMID:16928372
A novel mutation of WFS1 gene in a Japanese man of Wolfram syndrome with positive diabetes-related antibodies., PMID:16442662
Expressional and functional studies of Wolframin, the gene function deficient in Wolfram syndrome, in mice and patient cells., PMID:16087305
Wolfram syndrome: structural and functional analyses of mutant and wild-type wolframin, the WFS1 gene product., PMID:12913071
WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain., PMID:11181571
For research use only. Not for human or drug use.
