Catalog No.
PHB55001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human GABARAP (Met1-Leu117).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
MM46, GABA(A) receptor-associated protein, GABARAP, Gamma-aminobutyric acid receptor-associated protein, FLC3B
Purification
Purified by antigen affinity column.
Accession
O95166
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Enteric coronavirus nsp2 is a virulence determinant that recruits NBR1 for autophagic targeting of TBK1 to diminish the innate immune response., PMID:38597182
Synthetic autophagy receptor., PMID:37934826
Analysis of ATG8 Family Members Using LC3-Interacting Regions (LIR)-Based Molecular Traps., PMID:36446976
Secretion of pro-angiogenic extracellular vesicles during hypoxia is dependent on the autophagy-related protein GABARAPL1., PMID:34859607
The BAX-binding protein MOAP1 associates with LC3 and promotes closure of the phagophore., PMID:33783314
Novel Insights into the Cellular Localization and Regulation of the Autophagosomal Proteins LC3A, LC3B and LC3C., PMID:33081014
The GABARAP Co-Secretome Identified by APEX2-GABARAP Proximity Labelling of Extracellular Vesicles., PMID:32560054
Author Correction: The highly GABARAP specific rat monoclonal antibody 8H5 visualizes GABARAP in immunofluorescence imaging at endogenous levels., PMID:31822784
Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392
The highly GABARAP specific rat monoclonal antibody 8H5 visualizes GABARAP in immunofluorescence imaging at endogenous levels., PMID:30679523
Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense., PMID:28604719
Autophagy and ubiquitin-proteasome system contribute to sperm mitophagy after mammalian fertilization., PMID:27551072
Proximity Ligation In situ Assay is a Powerful Tool to Monitor Specific ATG Protein Interactions following Autophagy Induction., PMID:26034986
Sperm-inherited organelle clearance in C. elegans relies on LC3-dependent autophagosome targeting to the pericentrosomal area., PMID:25922527
Antibodies to inhibitory synaptic proteins in neurological syndromes associated with glutamic acid decarboxylase autoimmunity., PMID:25774787
Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs., PMID:25684710
[The stiff-person syndrome: a brief review and report of two cases]., PMID:24317357
Specific distribution of the autophagic protein GABARAPL1/GEC1 in the developing and adult mouse brain and identification of neuronal populations expressing GABARAPL1/GEC1., PMID:23690988
Phospholipase C-related catalytically inactive protein, a novel microtubule-associated protein 1 light chain 3-binding protein, negatively regulates autophagosome formation., PMID:23399561
Alteration of autophagosomal proteins in the brain of multiple system atrophy., PMID:22959883
Immunohistochemical analysis of Marinesco bodies, using antibodies against proteins implicated in the ubiquitin-proteasome system, autophagy and aggresome formation., PMID:22118216
GABARAPL1 antibodies: target one protein, get one free!, PMID:21862879
The acquisition of resistance to TNFα in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom microarray., PMID:21490427
Climbing fiber-evoked Purkinje cell discharge reduces expression of GABA(A) receptor-associated protein and decreases its interaction with GABA(A) receptors., PMID:21105873
Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation., PMID:20639871
A critical update on the immunopathogenesis of Stiff Person Syndrome., PMID:20636380
[Stiff-person syndrome and other myelopathies constitute paraneoplastic neurological syndromes]., PMID:20420178
Stiff person syndrome: advances in pathogenesis and therapeutic interventions., PMID:19210912
Monitoring autophagic degradation of p62/SQSTM1., PMID:19200883
Borna disease virus P protein affects neural transmission through interactions with gamma-aminobutyric acid receptor-associated protein., PMID:18815298
[Cloning and expression of human GABARAP and preparation of anti-GABARAP antibodies]., PMID:18464608
Specific regional distribution of gec1 mRNAs in adult rat central nervous system., PMID:18423580
In vivo selection of intrabodies specifically targeting protein-protein interactions: a general platform for an "undruggable" class of disease targets., PMID:18395925
Advances in the pathogenesis and treatment of patients with stiff person syndrome., PMID:18367039
C-terminal modification is required for GABARAP-mediated GABA(A) receptor trafficking., PMID:17581952
Autoimmunity to GABAA-receptor-associated protein in stiff-person syndrome., PMID:16984900
GABARAP is not essential for GABA receptor targeting to the synapse., PMID:16307606
GEC1, a protein related to GABARAP, interacts with tubulin and GABA(A) receptor., PMID:15530441
The subcellular distribution of GABARAP and its ability to interact with NSF suggest a role for this protein in the intracellular transport of GABA(A) receptors., PMID:11461150
Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation., PMID:11146101
The gamma-aminobutyric acid type A (GABAA) receptor-associated protein (GABARAP) promotes GABAA receptor clustering and modulates the channel kinetics., PMID:10984509
For research use only. Not for human or drug use.
