Catalog No.
YHD45001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys156-Glu256
Predicted molecular weight
25.45 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P21283
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATP6D, ATP6C, V-type proton ATPase subunit C 1, VATC, Vacuolar proton pump subunit C 1, ATP6V1C1, V-ATPase subunit C 1
Integrated thermal proteome and thermal proximity co-aggregation profiling identifies ATP6V1C1 as a novel anti-cancer drug target., PMID:40384877
Dominantly acting variants in ATP6V1C1 and ATP6V1B2 cause a multisystem phenotypic spectrum by altering lysosomal and/or autophagosome function., PMID:39210597
miRNAs from Inflamed Gingiva Link Gene Signaling to Increased MET Expression., PMID:37822091
Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosis., PMID:37402774
Identification and validation of autophagy-related genes in Kawasaki disease., PMID:37085930
A Novel Oxidative Phosphorylation-Associated Gene Signature for Prognosis Prediction in Patients with Hepatocellular Carcinoma., PMID:36105252
The FACT complex facilitates expression of lysosomal and antioxidant genes through binding to TFEB and TFE3., PMID:35230915
V-ATPase Inhibition Decreases Mutant Androgen Receptor Activity in Castrate-resistant Prostate Cancer., PMID:33563753
Comprehensive Analysis of ATP6V1s Family Members in Renal Clear Cell Carcinoma With Prognostic Values., PMID:33194650
The ATPase subunit of ATP6V1C1 inhibits autophagy and enhances radiotherapy resistance in esophageal squamous cell carcinoma., PMID:33183740
Multi-cancer V-ATPase molecular signatures: A distinctive balance of subunit C isoforms in esophageal carcinoma., PMID:31901859
C1 Silencing Attenuates Inflammation and Alveolar Bone Resorption in Endodontic Disease., PMID:31104818
MicroRNA29a Reverts the Activated Hepatic Stellate Cells in the Regression of Hepatic Fibrosis through Regulation of ATPase H⁺ Transporting V1 Subunit C1., PMID:30781750
Identification of novel prognosis-related genes associated with cancer using integrative network analysis., PMID:29459674
A multispecific monoclonal antibody G2 recognizes at least three completely different epitope sequences with high affinity., PMID:28791742
Osteoclast proton pump regulator Atp6v1c1 enhances breast cancer growth by activating the mTORC1 pathway and bone metastasis by increasing V-ATPase activity., PMID:28504970
Expression of ATP6V1C1 during oral carcinogenesis., PMID:26984774
Distinct Expression Patterns Of Causative Genes Responsible For Hereditary Progressive Hearing Loss In Non-Human Primate Cochlea., PMID:26915689
V-type ATPase proton pump expression during enamel formation., PMID:26586472
Targeting Atp6v1c1 Prevents Inflammation and Bone Erosion Caused by Periodontitis and Reveals Its Critical Function in Osteoimmunology., PMID:26274612
The use of tissue microarrays for semiquantitative evaluation of ATPaseC1 expression is ineffective., PMID:25901422
Identification and characterization of a multispecific monoclonal antibody G2 against chicken prion protein., PMID:24863561
Atp6v1c1 may regulate filament actin arrangement in breast cancer cells., PMID:24454753
Silencing of atp6v1c1 prevents breast cancer growth and bone metastasis., PMID:24155661
Transcriptome changes favoring intramuscular fat deposition in the longissimus muscle following castration of bulls., PMID:23893995
A 4-gene panel as a marker at chromosome 8q in Asian gastric cancer patients., PMID:23722107
A Drosophila model for genetic analysis of influenza viral/host interactions., PMID:21775472
Immunohistochemical localization of C1 subunit of V-ATPase (ATPase C1) in oral squamous cell cancer and normal oral mucosa., PMID:21526910
Measurement of ATP6V1C1 expression in brush cytology samples as a diagnostic and prognostic marker in oral squamous cell carcinoma., PMID:20404513
Atp6v1c1 is an essential component of the osteoclast proton pump and in F-actin ring formation in osteoclasts., PMID:18657050
Intracellular pH regulation in oral squamous cell carcinoma is mediated by increased V-ATPase activity via over-expression of the ATP6V1C1 gene., PMID:17467328
Distinct expression patterns of different subunit isoforms of the V-ATPase in the rat epididymis., PMID:16192400
Mouse proton pump ATPase C subunit isoforms (C2-a and C2-b) specifically expressed in kidney and lung., PMID:12947086
For research use only. Not for human or drug use.
