Catalog No.
YHK19701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met35-Val322
Predicted molecular weight
34.58 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96KB5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Nori-3, SPK, Lymphokine-activated killer T-cell-originated protein kinase, PDZ-binding kinase, Spermatogenesis-related protein kinase, PBK, TOPK, CT84, T-LAK cell-originated protein kinase, Cancer/testis antigen 84, MAPKK-like protein kinase
Real-world data on immune checkpoint inhibitors in advanced sarcomas across multiple European institutions., PMID:40495323
Unveiling the Therapeutic Potential of Targeting RRM2 in Hepatocellular Carcinoma: An Integrated In Silico and In Vitro Study., PMID:40493217
Managing pseudophakic bullous keratopathy with a topical rho kinase inhibitor: a case series., PMID:40340708
Correlation study of PBK/TOPK expression, prognosis, and immune infiltration in breast cancer., PMID:40301429
Identification of key hub genes and potential therapeutic drugs for nasopharyngeal carcinoma: Insights into molecular mechanisms and treatment strategies., PMID:40286596
Exploring the Interconnections Between Mitochondrial Dysfunction and Polycystic Ovary Syndrome: A Comprehensive Integrated Analysis., PMID:40259200
Molecular basis identification and hypnotic drug interactions for cognitive impairment related to sleep deprivation., PMID:40229714
PBK as a novel biomarker performed excellent diagnostic and prognostic value in HCC associated with immune infiltration and methylation., PMID:40178670
Quantitative in vitro-to-in vivo extrapolation of human adrenergic and trace amine-associated receptor 1 potencies of pre-workout supplement ingredients using physiologically based kinetic modelling-based reverse dosimetry., PMID:40178592
PBK-TD modelling of the gonadotropic axis: Case study with two azole fungicides in female zebrafish., PMID:40158424
CENPF as a prognostic marker of glioma: unraveling the molecular mechanisms., PMID:40019588
CLDN6 triggers NRF2-mediated ferroptosis through recruiting DLG1/PBK complex in breast cancer., PMID:39984471
Integrative Bioinformatics Analysis for Targeting Hub Genes in Hepatocellular Carcinoma Treatment., PMID:39911278
Studying interaction effects on toxicokinetics in zebrafish combining experimental and modelling approaches., PMID:39892242
Protein tyrosine phosphatase PTPH1 potentiates receptor tyrosine kinase HER2 oncogenesis via a PDZ-coupled and phosphorylation-driven scaffold., PMID:39803648
VAMP8 as a biomarker and potential therapeutic target for endothelial cell dysfunction in atherosclerosis., PMID:39800194
The bioinformatics analysis and experimental validation of the carcinogenic role of EXO1 in lung adenocarcinoma., PMID:39777332
The miRNA-mRNA Regulatory Network in Human Hepatocellular Carcinoma by Transcriptomic Analysis From GEO., PMID:39764737
Spatially dependent tissue distribution of thyroid hormones by plasma thyroid hormone binding proteins., PMID:39751918
Application of physiologically based (PBK) modeling to quantify the effect of the antibiotic tobramycin on bile acid levels in human plasma., PMID:39731603
Construction of a prognostic model based on disulfidptosis-related genes and identification of CCNA2 as a novel biomarker for hepatocellular carcinoma., PMID:39695705
Prospective observational study of FKRP-related limb-girdle muscular dystrophy R9: A GRASP consortium study., PMID:39675022
Unraveling the role of PBK in glioblastoma: from molecular mechanisms to therapeutic targets., PMID:39649886
Comparative Efficacy of Tumor Microenvironment-responsive Nanotherapeutics Targeting PSD95/Discs-large/ZO-1 Binding Kinase in Different Histological Subgroups of Medulloblastoma., PMID:39628686
Bioinformatics-based screening of hub genes for prostate cancer bone metastasis and analysis of immune infiltration., PMID:39560511
Proteomics and Metabolomics Study on the Responses of Sertoli Cells Infected With Brucella and Its bvfA-Deletion Strains., PMID:39512196
Unveiling novel prognostic biomarkers and therapeutic targets for HBV-associated hepatocellular carcinoma through integrated bioinformatic analysis., PMID:39470543
Exploring common pathogenic association between Epstein Barr virus infection and long-COVID by integrating RNA-Seq and molecular dynamics simulations., PMID:39391317
The single-cell transcriptome of mTECs and CD4+ thymocytes under adhesion revealed heterogeneity of mTECs and a network controlled by Aire and lncRNAs., PMID:39328409
Elucidating the molecular interactions and immune modulation of bisphenols exposure in the pathogenesis of polycystic ovary syndrome., PMID:39313041
Identification of Hub Genes in Comorbidity of Psoriasis and Vitiligo Using Bioinformatics Analysis., PMID:39258216
DEPDC1B: A novel tumor suppressor gene associated with immune infiltration in colon adenocarcinoma., PMID:39087856
Physiologically based Kinetic Modeling-Facilitated Quantitative In Vitro to In Vivo Extrapolation to Predict the Effects of Aloe-Emodin in Rats and Humans., PMID:38980703
WZ-3146 acts as a novel small molecule inhibitor of KIF4A to inhibit glioma progression by inducing apoptosis., PMID:38937742
Application of partition coefficient methods to predict tissue:plasma affinities in common farm animals: Influence of ionisation state., PMID:38925423
Contribution of human organic anion transporter 3-mediated transport of a major linezolid metabolite, PNU-142586, in linezolid-induced thrombocytopenia., PMID:38781867
From hazard to risk prioritization: a case study to predict drug-induced cholestasis using physiologically based kinetic modeling., PMID:38755481
Immune profiling of dedifferentiated liposarcoma and identification of novel antigens for targeted immunotherapy., PMID:38755218
PDZ-Binding Kinase, a Novel Regulator of Vascular Remodeling in Pulmonary Arterial Hypertension., PMID:38682326
The role and mechanism of PDZ binding kinase in hypobaric and hypoxic acute lung injury., PMID:38617778
Small-molecule inhibitor HI-TOPK-032 improves NK-92MI cell infiltration into ovarian tumours., PMID:38501576
In vitro-in silico study on the influence of dose, fraction bioactivated and endpoint used on the relative potency value of pyrrolizidine alkaloid N-oxides compared to parent pyrrolizidine alkaloids., PMID:38469320
FHND004 inhibits malignant proliferation of multiple myeloma by targeting PDZ-binding kinase in MAPK pathway., PMID:38460944
Chemical modification of bradykinin-polymer conjugates for optimum delivery of nanomedicines to tumors., PMID:38460653
Identification and validation of a novel 9-gene signature of non-specific classification to predict prognosis in glioma patients., PMID:38372105
Phosphorylation of PBK at Thr9 by CDK5 correlates with invasion of prolactinomas., PMID:38363020
Multiple-Pathway Synergy Alters Steroidogenesis and Spermatogenesis in Response to an Immunocastration Vaccine in Goat., PMID:38201210
Spatially Dependent Tissue Distribution of Thyroid Hormones by Plasma Thyroid Hormone Binding Proteins., PMID:38187691
Exploring the role of PRDX4 in the development of uterine corpus endometrial carcinoma., PMID:38177789
Machine learning and experimental screening of chromatin regulator signatures and potential drugs in hepatitis B related hepatocellular carcinoma., PMID:38111163
For research use only. Not for human or drug use.
