Catalog No.
YHF13201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Val128
Predicted molecular weight
16.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P55769
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
High mobility group-like nuclear protein 2 homolog 1, SNU13, U4/U6.U5 tri-snRNP 15.5 kDa protein, OTK27, hSNU13, SNU13 homolog, U4/U6.U5 small nuclear ribonucleoprotein SNU13, NHP2-like protein 1, NHP2L1
Therapy-induced secretion of spliceosomal components mediates pro-survival crosstalk between ovarian cancer cells., PMID:38898005
Revealing the potential role of hub metabolism-related genes and their correlation with immune cells in acute ischemic stroke., PMID:38850201
Prognostic value of RNF113A shows a correlation with immune infiltrates in colorectal cancer., PMID:38715816
Alternative splicing shapes the transcriptome complexity in blackgram [Vigna mungo (L.) Hepper]., PMID:37133618
Comprehensive Analysis of Splicing Factor and Alternative Splicing Event to Construct Subtype-Specific Prognosis-Predicting Models for Breast Cancer., PMID:34630526
Gene Expression Alteration of Sperm-Associated Antigens in Human Cryopreserved Sperm., PMID:34009011
Identification of small molecules that mitigate vincristine-induced neurotoxicity while sensitizing leukemia cells to vincristine., PMID:33742760
High-resolution structure of eukaryotic Fibrillarin interacting with Nop56 amino-terminal domain., PMID:33483369
Box C/D snoRNPs: solid-state NMR fingerprint of an early-stage 50 kDa assembly intermediate., PMID:32030621
A conserved Bcd1 interaction essential for box C/D snoRNP biogenesis., PMID:31537647
The yeast C/D box snoRNA U14 adopts a "weak" K-turn like conformation recognized by the Snu13 core protein in solution., PMID:30914254
Bcd1p controls RNA loading of the core protein Nop58 during C/D box snoRNP biogenesis., PMID:30700579
Alteration of RNA Splicing by Small-Molecule Inhibitors of the Interaction between NHP2L1 and U4., PMID:28985478
Implication of the box C/D snoRNP assembly factor Rsa1p in U3 snoRNP assembly., PMID:28505348
Structural Features of the Box C/D snoRNP Pre-assembly Process Are Conserved through Species., PMID:27594683
Substrate-assisted mechanism of RNP disruption by the spliceosomal Brr2 RNA helicase., PMID:27354531
Conserved structure of Snu13 from the highly reduced spliceosome of Cyanidioschyzon merolae., PMID:26833716
Assembly and dynamics of the U4/U6 di-snRNP by single-molecule FRET., PMID:26503251
NUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins., PMID:26275778
A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing., PMID:26161500
Genome-wide analysis of small nucleolar RNAs of Leishmania major reveals a rich repertoire of RNAs involved in modification and processing of rRNA., PMID:25970223
Nop17 is a key R2TP factor for the assembly and maturation of box C/D snoRNP complex., PMID:25888478
Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control., PMID:25404746
Protein Hit1, a novel box C/D snoRNP assembly factor, controls cellular concentration of the scaffolding protein Rsa1 by direct interaction., PMID:25170085
Nutritional status modulates box C/D snoRNP biogenesis by regulated subcellular relocalization of the R2TP complex., PMID:25060708
Mutational screening of splicing factor genes in cases with autosomal dominant retinitis pigmentosa., PMID:24959063
Genome-wide DNA methylation analysis of patients with imprinting disorders identifies differentially methylated regions associated with novel candidate imprinted genes., PMID:24501229
Characterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly., PMID:24234454
Post-transcriptional regulation of myotube elongation and myogenesis by Hoi Polloi., PMID:23942517
Structural and functional analysis of the U3 snoRNA binding protein Rrp9., PMID:23509373
A proteomic screen for nucleolar SUMO targets shows SUMOylation modulates the function of Nop5/Nop58., PMID:20797632
Assignment of 1H, 13C, and 15N resonances of the RNA binding protein Snu13p from Saccharomyces cerevisiae., PMID:19636910
Evidence that the AAA+ proteins TIP48 and TIP49 bridge interactions between 15.5K and the related NOP56 and NOP58 proteins during box C/D snoRNP biogenesis., PMID:19620283
Functional implications for a prototypical K-turn binding protein from structural and dynamical studies of 15.5K., PMID:18044964
Elucidating the role of C/D snoRNA in rRNA processing and modification in Trypanosoma brucei., PMID:17981991
A dynamic scaffold of pre-snoRNP factors facilitates human box C/D snoRNP assembly., PMID:17636026
Analysis of pre-mRNA and pre-rRNA processing factor Snu13p structure and mutants., PMID:17631273
An improved definition of the RNA-binding specificity of SECIS-binding protein 2, an essential component of the selenocysteine incorporation machinery., PMID:17332014
Analysis of sequence and structural features that identify the B/C motif of U3 small nucleolar RNA as the recognition site for the Snu13p-Rrp9p protein pair., PMID:17145781
NMR assignment of the human spliceosomal 15.5K protein., PMID:17122951
Protein-protein and protein-RNA contacts both contribute to the 15.5K-mediated assembly of the U4/U6 snRNP and the box C/D snoRNPs., PMID:16782898
Structural comparison of yeast snoRNP and spliceosomal protein Snu13p with its homologs., PMID:15963469
Characterization of Saccharomyces cerevisiae Nop17p, a novel Nop58p-interacting protein that is involved in Pre-rRNA processing., PMID:15670595
The snRNP 15.5K protein folds its cognate K-turn RNA: a combined theoretical and biochemical study., PMID:15659359
The archaeal sRNA binding protein L7Ae has a 3D structure very similar to that of its eukaryal counterpart while having a broader RNA-binding specificity., PMID:15342235
Structure of protein L7Ae bound to a K-turn derived from an archaeal box H/ACA sRNA at 1.8 A resolution., PMID:15130481
Analysis of Snu13p mutations reveals differential interactions with the U4 snRNA and U3 snoRNA., PMID:14730029
U4 snRNA nucleolar localization requires the NHPX/15.5-kD protein binding site but not Sm protein or U6 snRNA association., PMID:12939253
A structural, phylogenetic, and functional study of 15.5-kD/Snu13 protein binding on U3 small nucleolar RNA., PMID:12810916
Conserved stem II of the box C/D motif is essential for nucleolar localization and is required, along with the 15.5K protein, for the hierarchical assembly of the box C/D snoRNP., PMID:12417735
For research use only. Not for human or drug use.
