Catalog No.
YHA97101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser282
Predicted molecular weight
33.99 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O60671
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DNA repair exonuclease rad1 homolog, Rad1-like DNA damage checkpoint protein, RAD1, REC1, hRAD1, Cell cycle checkpoint protein RAD1
The Slx4-Rad1-Rad10 nuclease differentially regulates deletions and duplications induced by a replication fork barrier., PMID:40446207
CARM1/PRMT4 facilitates XPF-ERCC1 heterodimer assembly and maintains nucleotide excision repair activity., PMID:40304182
Thyroid hormone receptor interacting protein 13 is associated with prognosis and immunotherapy efficacy in human cancers: a pan-cancer analysis., PMID:40253660
The differential roles of rad9 alternatively spliced forms in double- strand DNA break repair during Drosophila meiosis., PMID:40250145
SLX4 and XPF are involved in cell migration and EMT in a cell-specific manner., PMID:40118290
Genome-Wide Identification, Expression, and Protein Interaction of GRAS Family Genes During Arbuscular Mycorrhizal Symbiosis in Poncirus trifoliata., PMID:40076705
Centromeres are stress-induced fragile sites., PMID:39970915
Beyond Nucleotide Excision Repair: The Importance of XPF in Base Excision Repair and Its Impact on Cancer, Inflammation, and Aging., PMID:39769376
Unveiling Secondary Mutations in Blended Phenotypes: Dual ERCC4 and OTOA Pathogenic Variants Through WES Analysis., PMID:39769235
Beyond Huntington's Disease - Late-Onset Chorea Caused by a Homozygous Variant in ERCC4., PMID:39652212
Minute virus of mice NS1 redirects casein kinase 2 specificity to suppress the ATR DNA damage response pathway during infection., PMID:39565137
TORC2 inhibition triggers yeast chromosome fragmentation through misregulated Base Excision Repair of clustered oxidation events., PMID:39548071
The synergy between alkylating agents and ERCC1-XPF inhibitors is p53 dependent., PMID:39520092
Molecular architecture and functional dynamics of the pre-incision complex in nucleotide excision repair., PMID:39353945
Psoriatic skin transcript phenotype: androgen/estrogen and cortisone/cortisol imbalance with increasing DNA damage response., PMID:39180588
RHNO1: at the crossroads of DNA replication stress, DNA repair, and cancer., PMID:39107463
Significance of Ribonucleoside-diphosphate Reductase Subunit M2 in Lung Adenocarcinoma., PMID:38920074
The enhanced energy metabolism in the tumor margin mediated by RRAD promotes the progression of oral squamous cell carcinoma., PMID:38811531
Persistent TFIIH binding to non-excised DNA damage causes cell and developmental failure., PMID:38664429
Two siblings with Fanconi anemia (FANCQ, ERCC4/XPF) presenting with tumor-mimicking lesions in the brain and acute neurological deterioration., PMID:38644609
Structural basis for intra- and intermolecular interactions on RAD9 subunit of 9-1-1 checkpoint clamp implies functional 9-1-1 regulation by RHINO., PMID:38354779
Resection of DNA double-strand breaks activates Mre11-Rad50-Nbs1- and Rad9-Hus1-Rad1-dependent mechanisms that redundantly promote ATR checkpoint activation and end processing in Xenopus egg extracts., PMID:38349040
Nonhomologous tails direct heteroduplex rejection and mismatch correction during single-strand annealing in Saccharomyces cerevisiae., PMID:38315739
Multiple DNA repair pathways prevent acetaldehyde-induced mutagenesis in yeast., PMID:38260495
Rad2, Rad14 and Rad26 recover Metarhizium robertsii from solar UV damage through photoreactivation in vivo., PMID:38154444
Human Ribonuclease 6 Has a Protective Role during Experimental Urinary Tract Infection., PMID:37980892
Double-strand breaks induce inverted duplication chromosome rearrangements by a DNA polymerase δ-dependent mechanism., PMID:37919272
The dynamic subcellular localisation of Rad1 is cell cycle dependent in Leishmania major., PMID:37918502
The C-terminal tail of Rad17, iVERGE, binds the 9‒1‒1 complex independently of AAA+ ATPase domains to provide another clamp-loader interface., PMID:37713925
Using Affinity Pulldown Assays to Study Protein-Protein Interactions of Human NEIL1 Glycosylase and the Checkpoint Protein RAD9-RAD1-HUS1 (9-1-1) Complex., PMID:37574484
Expression of RAD9B in the mesostriatal system of rats and humans: Overexpression in a 6-OHDA rat model of Parkinson's disease., PMID:37460044
RHINO directs MMEJ to repair DNA breaks in mitosis., PMID:37440612
Genetic control of the error-prone repair of a chromosomal double-strand break with 5' overhangs in yeast., PMID:37418686
Rad1 attenuates DNA double-strand breaks and cell cycle arrest in type II alveolar epithelial cells of rats with bronchopulmonary dysplasia., PMID:37226090
RAD51-WSS1-dependent genetic pathways are essential for DNA-protein crosslink repair and pathogenesis in Candida albicans., PMID:37080389
Friend or Foe: Regulation, Downstream Effectors of RRAD in Cancer., PMID:36979412
Widely spaced and divergent inverted repeats become a potent source of chromosomal rearrangements in long single-stranded DNA regions., PMID:36919609
Identification of a novel carbapenem-hydrolysing class D β-lactamase RAD-1 in Riemerella anatipestifer., PMID:36883515
The 9-1-1 DNA clamp subunit RAD1 forms specific interactions with clamp loader RAD17, revealing functional implications for binding-protein RHINO., PMID:36841485
RAD51 and RAD51B Play Diverse Roles in the Repair of DNA Double Strand Breaks in Physcomitrium patens., PMID:36833232
S-PI-RADS and PI-RRADS for Biparametric MRI in the Detection of Prostate Cancer and Post-treatment Local Recurrence., PMID:36585156
R-loop-derived cytoplasmic RNA-DNA hybrids activate an immune response., PMID:36544021
Efficient Photoreactivation of Solar UV-Injured Metarhizium robertsii by Rad1 and Rad10 Linked to DNA Photorepair-Required Proteins., PMID:36441642
Rad1 and Rad10 Tied to Photolyase Regulators Protect Insecticidal Fungal Cells from Solar UV Damage by Photoreactivation., PMID:36354891
TRIM36 enhances lung adenocarcinoma radiosensitivity and inhibits tumorigenesis through promoting RAD51 ubiquitination and antagonizing hsa-miR-376a-5p., PMID:36058131
Repair of mismatched templates during Rad51-dependent Break-Induced Replication., PMID:36054210
DNA binding by the Rad9A subunit of the Rad9-Rad1-Hus1 complex., PMID:35939452
RNASE6 is a novel modifier of APOE-ε4 effects on cognition., PMID:35896049
Structure of the human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp bound to a dsDNA-ssDNA junction., PMID:35819203
Genotoxic hazard assessment of cerium oxide and magnesium oxide nanoparticles in Drosophila., PMID:35818303
For research use only. Not for human or drug use.
