Catalog No.
YHK49601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys22-Ala96
Predicted molecular weight
10.76 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96DH6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Musashi-2, RNA-binding protein Musashi homolog 2, MSI2
Comparison of MALDI-TOF MS instruments and databases for the identification of uncommon yeasts, Aspergillus spp. and rare filamentous fungi., PMID:40372046
Prognostic Role of Musashi-2 Immunohistochemical Expression and CD163+ Tumor- Associated Macrophages in Colorectal Cancer Progression., PMID:40302097
β-Catenin interacts with canonical RBPs including MSI2 to associate with a Wnt signalling mRNA network in myeloid leukaemia cells., PMID:40301545
Specific MSI2 deletion maintains intestinal barrier integrity by down-regulating ILC3s-derived IL-17 a in mice with colitis., PMID:40279942
Blocking MSI2 alleviated radiation-induced pulmonary fibrosis through inhibiting epithelial-mesenchymal transition., PMID:40227576
Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation., PMID:40196615
Dissecting RNA selectivity mediated by tandem RNA-binding domains., PMID:40120682
The Super Enhancer-Driven Long Noncoding RNA PRKCQ-AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds., PMID:40103284
Regulation of lung cancer initiation and progression by the stem cell determinant Musashi., PMID:40047406
Prolonged DEHP exposure enhances the stemness and metastatic potential of TNBC cells in an MSI2-dependent manner., PMID:39990676
ELK4 transcription promotes MSI2-mediated progression of non-small cell lung cancer through the TGF-β/SMAD3 pathway., PMID:39969091
Update on the Progress of Musashi-2 in Malignant Tumors., PMID:39862069
LncRNA FGD5-AS1 Facilitates Hepatocellular Carcinoma Cell Stemness by Enhancing PKD1 mRNA Stability Through Binding With MSI2., PMID:39803743
HuD regulates apoptosis in N2a cells by regulating Msi2 expression., PMID:39680531
Arabidopsis histone acetyltransferase complex coordinates cytoplasmic histone acetylation and nuclear chromatin accessibility., PMID:39630902
A novel regulatory axis of MSI2-AGO2/miR-30a-3p-CGRRF1 drives cancer chemoresistance by upregulating the KRAS/ERK pathway., PMID:39522321
MSI2 regulates NLK-mediated EMT and PI3K/AKT/mTOR pathway to promote pancreatic cancer progression., PMID:39097735
A novel interaction between the 5' untranslated region of the Chikungunya virus genome and Musashi RNA binding protein is essential for efficient virus genome replication., PMID:39087525
CircMALAT1 promotes cancer stem-like properties and chemoresistance via regulating Musashi-2/c-Myc axis in esophageal squamous cell carcinoma., PMID:38881674
Transcription factor FOXF2 promotes the development and progression of pancreatic cancer by targeting MSI2., PMID:38847273
Therapeutic potential of oleic acid supplementation in myotonic dystrophy muscle cell models., PMID:38760841
DNA methylation and type 2 diabetes: a systematic review., PMID:38755631
Musashi-2 (MSI2) regulation of DNA damage response in lung cancer., PMID:38659828
Conditioned medium-enriched umbilical cord mesenchymal stem cells: a potential therapeutic strategy for spinal cord injury, unveiling transcriptomic and secretomic insights., PMID:38658405
Mechanism of Musashi2 affecting radiosensitivity of lung cancer by modulating DNA damage repair., PMID:38645664
Tracking pairwise genomic loci by the ParB-ParS and Noc-NBS systems in living cells., PMID:38412314
The RNA-binding protein Msi2 regulates autophagy during myogenic differentiation., PMID:38373797
Musashi-2 potentiates colorectal cancer immune infiltration by regulating the post-translational modifications of HMGB1 to promote DCs maturation and migration., PMID:38347600
Darwin, MSI2, and relapse in T-ALL., PMID:38270944
MSI2 Modulates Unsaturated Fatty Acid Metabolism by Binding FASN in Bovine Mammary Epithelial Cells., PMID:38059915
Defining Distinct RNA-Protein Interactomes of SARS-CoV-2 Genomic and Subgenomic RNAs., PMID:38043095
Musashi-2 Deficiency Triggers Colorectal Cancer Ferroptosis by Downregulating the MAPK Signaling Cascade to Inhibit HSPB1 Phosphorylation., PMID:38041016
Musashi-2 in cancer-associated fibroblasts promotes non-small cell lung cancer metastasis through paracrine IL-6-driven epithelial-mesenchymal transition., PMID:37941042
Musashi-2 causes cardiac hypertrophy and heart failure by inducing mitochondrial dysfunction through destabilizing Cluh and Smyd1 mRNA., PMID:37923788
Musashi-2 (MSI2) promotes neuroblastoma tumorigenesis through targeting MYC-mediated glucose-6-phosphate dehydrogenase (G6PD) transcriptional activation., PMID:37843625
Clonal evolution dissection reveals that a high MSI2 level promotes chemoresistance in T-cell acute lymphoblastic leukemia., PMID:37801708
Msi2 enhances muscle dysfunction in a myotonic dystrophy type 1 mouse model., PMID:37797921
Down-regulation of Musashi-2 exerts antileukemic effects on acute lymphoblastic leukemia cells and increases sensitivity to dexamethasone., PMID:37749318
Identification and functional validation of SRC and RAPGEF1 as new direct targets of miR-203, involved in regulation of epidermal homeostasis., PMID:37635193
Musashi-2 binds with Fbxo6 to induce Rnaset2 ubiquitination and chemokine signaling pathway during vascular smooth muscle cell phenotypic switch in atherosclerosis., PMID:37633478
Lack of Musashi-2 induces type IIa fiber-dominated muscle atrophy., PMID:37606581
Exploring the role of m6A methylation regulators in glioblastoma multiforme and their impact on the tumor immune microenvironment., PMID:37606566
Schizophrenia in the genetic era: a review from development history, clinical features and genomic research approaches to insights of susceptibility genes., PMID:37542622
Dysregulated Stem Cell Markers Musashi-1 and Musashi-2 are Associated with Therapy Resistance in Inflammatory Breast Cancer., PMID:37481823
Musashi-2 (MSI2) regulation of DNA damage response in lung cancer., PMID:37398283
Small-molecule Ro-08-2750 interacts with many RNA-binding proteins and elicits MUSASHI2-independent phenotypes., PMID:37369529
Defining distinct RNA-protein interactomes of SARS-CoV-2 genomic and subgenomic RNAs., PMID:37293069
Transcriptome sequencing identifies novel EVX fusions involved in transcriptional activation of HOX family genes in pediatric immature T-cell acute lymphoblastic leukemia: two cases reports and a literature review., PMID:37243888
Regulation of VEGFR2 and AKT Signaling by Musashi-2 in Lung Cancer., PMID:37173995
MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia., PMID:37149661