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Recombinant Human MSI2 Protein, N-His

Catalog #:   YHK49601 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: Q96DH6
Protein length: Lys22-Ala96
Overview

Catalog No.

YHK49601

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Lys22-Ala96

Predicted molecular weight

10.76 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q96DH6

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Musashi-2, RNA-binding protein Musashi homolog 2, MSI2

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human MSI2 Protein
References

Comparison of MALDI-TOF MS instruments and databases for the identification of uncommon yeasts, Aspergillus spp. and rare filamentous fungi., PMID:40372046

Prognostic Role of Musashi-2 Immunohistochemical Expression and CD163+ Tumor- Associated Macrophages in Colorectal Cancer Progression., PMID:40302097

β-Catenin interacts with canonical RBPs including MSI2 to associate with a Wnt signalling mRNA network in myeloid leukaemia cells., PMID:40301545

Specific MSI2 deletion maintains intestinal barrier integrity by down-regulating ILC3s-derived IL-17 a in mice with colitis., PMID:40279942

Blocking MSI2 alleviated radiation-induced pulmonary fibrosis through inhibiting epithelial-mesenchymal transition., PMID:40227576

Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation., PMID:40196615

Dissecting RNA selectivity mediated by tandem RNA-binding domains., PMID:40120682

The Super Enhancer-Driven Long Noncoding RNA PRKCQ-AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds., PMID:40103284

Regulation of lung cancer initiation and progression by the stem cell determinant Musashi., PMID:40047406

Prolonged DEHP exposure enhances the stemness and metastatic potential of TNBC cells in an MSI2-dependent manner., PMID:39990676

ELK4 transcription promotes MSI2-mediated progression of non-small cell lung cancer through the TGF-β/SMAD3 pathway., PMID:39969091

Update on the Progress of Musashi-2 in Malignant Tumors., PMID:39862069

LncRNA FGD5-AS1 Facilitates Hepatocellular Carcinoma Cell Stemness by Enhancing PKD1 mRNA Stability Through Binding With MSI2., PMID:39803743

HuD regulates apoptosis in N2a cells by regulating Msi2 expression., PMID:39680531

Arabidopsis histone acetyltransferase complex coordinates cytoplasmic histone acetylation and nuclear chromatin accessibility., PMID:39630902

A novel regulatory axis of MSI2-AGO2/miR-30a-3p-CGRRF1 drives cancer chemoresistance by upregulating the KRAS/ERK pathway., PMID:39522321

MSI2 regulates NLK-mediated EMT and PI3K/AKT/mTOR pathway to promote pancreatic cancer progression., PMID:39097735

A novel interaction between the 5' untranslated region of the Chikungunya virus genome and Musashi RNA binding protein is essential for efficient virus genome replication., PMID:39087525

CircMALAT1 promotes cancer stem-like properties and chemoresistance via regulating Musashi-2/c-Myc axis in esophageal squamous cell carcinoma., PMID:38881674

Transcription factor FOXF2 promotes the development and progression of pancreatic cancer by targeting MSI2., PMID:38847273

Therapeutic potential of oleic acid supplementation in myotonic dystrophy muscle cell models., PMID:38760841

DNA methylation and type 2 diabetes: a systematic review., PMID:38755631

Musashi-2 (MSI2) regulation of DNA damage response in lung cancer., PMID:38659828

Conditioned medium-enriched umbilical cord mesenchymal stem cells: a potential therapeutic strategy for spinal cord injury, unveiling transcriptomic and secretomic insights., PMID:38658405

Mechanism of Musashi2 affecting radiosensitivity of lung cancer by modulating DNA damage repair., PMID:38645664

Tracking pairwise genomic loci by the ParB-ParS and Noc-NBS systems in living cells., PMID:38412314

The RNA-binding protein Msi2 regulates autophagy during myogenic differentiation., PMID:38373797

Musashi-2 potentiates colorectal cancer immune infiltration by regulating the post-translational modifications of HMGB1 to promote DCs maturation and migration., PMID:38347600

Darwin, MSI2, and relapse in T-ALL., PMID:38270944

MSI2 Modulates Unsaturated Fatty Acid Metabolism by Binding FASN in Bovine Mammary Epithelial Cells., PMID:38059915

Defining Distinct RNA-Protein Interactomes of SARS-CoV-2 Genomic and Subgenomic RNAs., PMID:38043095

Musashi-2 Deficiency Triggers Colorectal Cancer Ferroptosis by Downregulating the MAPK Signaling Cascade to Inhibit HSPB1 Phosphorylation., PMID:38041016

Musashi-2 in cancer-associated fibroblasts promotes non-small cell lung cancer metastasis through paracrine IL-6-driven epithelial-mesenchymal transition., PMID:37941042

Musashi-2 causes cardiac hypertrophy and heart failure by inducing mitochondrial dysfunction through destabilizing Cluh and Smyd1 mRNA., PMID:37923788

Musashi-2 (MSI2) promotes neuroblastoma tumorigenesis through targeting MYC-mediated glucose-6-phosphate dehydrogenase (G6PD) transcriptional activation., PMID:37843625

Clonal evolution dissection reveals that a high MSI2 level promotes chemoresistance in T-cell acute lymphoblastic leukemia., PMID:37801708

Msi2 enhances muscle dysfunction in a myotonic dystrophy type 1 mouse model., PMID:37797921

Down-regulation of Musashi-2 exerts antileukemic effects on acute lymphoblastic leukemia cells and increases sensitivity to dexamethasone., PMID:37749318

Identification and functional validation of SRC and RAPGEF1 as new direct targets of miR-203, involved in regulation of epidermal homeostasis., PMID:37635193

Musashi-2 binds with Fbxo6 to induce Rnaset2 ubiquitination and chemokine signaling pathway during vascular smooth muscle cell phenotypic switch in atherosclerosis., PMID:37633478

Lack of Musashi-2 induces type IIa fiber-dominated muscle atrophy., PMID:37606581

Exploring the role of m6A methylation regulators in glioblastoma multiforme and their impact on the tumor immune microenvironment., PMID:37606566

Schizophrenia in the genetic era: a review from development history, clinical features and genomic research approaches to insights of susceptibility genes., PMID:37542622

Dysregulated Stem Cell Markers Musashi-1 and Musashi-2 are Associated with Therapy Resistance in Inflammatory Breast Cancer., PMID:37481823

Musashi-2 (MSI2) regulation of DNA damage response in lung cancer., PMID:37398283

Small-molecule Ro-08-2750 interacts with many RNA-binding proteins and elicits MUSASHI2-independent phenotypes., PMID:37369529

Defining distinct RNA-protein interactomes of SARS-CoV-2 genomic and subgenomic RNAs., PMID:37293069

Transcriptome sequencing identifies novel EVX fusions involved in transcriptional activation of HOX family genes in pediatric immature T-cell acute lymphoblastic leukemia: two cases reports and a literature review., PMID:37243888

Regulation of VEGFR2 and AKT Signaling by Musashi-2 in Lung Cancer., PMID:37173995

MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia., PMID:37149661

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human MSI2 Protein, N-His [YHK49601]
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