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Recombinant Human PSPH Protein, N-His

Catalog #:   YHF64301 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P78330
Protein length: Met1-Glu225
Overview

Catalog No.

YHF64301

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Met1-Glu225

Predicted molecular weight

27.17 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P78330

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

O-phosphoserine phosphohydrolase, Phosphoserine phosphatase, L-3-phosphoserine phosphatase, PSP, PSPH, PSPase

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human PSPH Protein
References

PSPH promotes the proliferation and metastasis of esophageal squamous cell carcinoma through MAPK signaling pathways., PMID:40371136

Architecture of genome-wide transcriptional regulatory network reveals dynamic functions and evolutionary trajectories in Pseudomonas syringae., PMID:40162990

FOXC1-mediated serine metabolism reprogramming enhances colorectal cancer growth and 5-FU resistance under serine restriction., PMID:39773485

N6-Methyladenosine modification activates the serine synthesis pathway to mediate therapeutic resistance in liver cancer., PMID:39489921

Global, regional, and national burden of stroke and its risk factors, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021., PMID:39304265

Knockdown of ERN1 disturbs the expression of phosphoserine aminotransferase 1 and related genes in glioblastoma cells., PMID:39059599

The m6A writer RBM15 drives the growth of triple-negative breast cancer cells through the stimulation of serine and glycine metabolism., PMID:38825643

L-serine deficiency: on the properties of the Asn133Ser variant of human phosphoserine phosphatase., PMID:38816452

Skeletal muscle hypertrophy rewires glucose metabolism: An experimental investigation and systematic review., PMID:38742477

Composite alginate-based hydrogel delivery of antioxidant pumpkin protein hydrolysate in simulated gastrointestinal condition., PMID:38708103

Multi-layer encapsulation of pumpkin (Cucurbita maxima L.) seed protein hydrolysate and investigating its release and antioxidant activity in simulated gastrointestinal digestion., PMID:38681570

Inhibition of signaling protein ERN1 increases the sensitivity of serine synthesis gene expressions to glucose and glutamine deprivations in U87MG glioblastoma cells., PMID:38656254

Deciphering the Impact of Rare Missense Variants in EGFR-TKI-Resistant Non-Small-Cell Lung Cancer through Whole Exome Sequencing: A Computational Approach., PMID:38617633

Augmented Mitochondrial Transfer Involved in Astrocytic PSPH Attenuates Cognitive Dysfunction in db/db Mice., PMID:38573412

Effect of exercise-based rehabilitation on functional capacity and renal function in type 2 diabetes mellitus with nephropathy: a randomized controlled trial., PMID:38483735

AMPK-HIF-1α signaling enhances glucose-derived de novo serine biosynthesis to promote glioblastoma growth., PMID:38098117

A Comprehensive Bioinformatics Resource Guide for Genome-Based Antimicrobial Resistance Studies., PMID:37861712

Hypoxia controls the expression of genes responsible for serine synthesis in U87MG cells on ERN1-dependent manner., PMID:37823569

Constructing and interpreting a large-scale variant effect map for an ultrarare disease gene: Comprehensive prediction of the functional impact of PSAT1 genotypes., PMID:37812589

The Dipeptide Gly-Pro (GP), Derived from Hibiscus sabdariffa, Exhibits Potent Antifibrotic Effects by Regulating the TGF-β1-ATF4-Serine/Glycine Biosynthesis Pathway., PMID:37686422

Integrated of multi-omics and molecular docking reveal PHGDH, PSAT1 and PSPH in the serine synthetic pathway as potential targets of T-2 toxin exposure in pig intestinal tract., PMID:37678681

Increased serine synthesis in cumulus cells of young infertile women with diminished ovarian reserve., PMID:37533289

Influence of the concentrate inclusion level in a grass silage-based diet on hepatic transcriptomic profiles in Holstein-Friesian dairy cows in early lactation., PMID:37474362

Novel genes associated with a placental phenotype in knockout mice also respond to cellular stressors in primary human trophoblasts., PMID:37331027

Study on the Mechanism of MC5R Participating in Energy Metabolism of Goose Liver., PMID:37239994

Downregulation of phosphoserine phosphatase potentiates tumor immune environments to enhance immune checkpoint blockade therapy., PMID:36849198

Predicting the functional effect of compound heterozygous genotypes from large scale variant effect maps., PMID:36711904

Multi-omics Analysis of the Role of PHGDH in Colon Cancer., PMID:36707056

ABRO1 arrests cardiomyocyte proliferation and myocardial repair by suppressing PSPH., PMID:36639869

Probing Folate-Responsive and Stage-Sensitive Metabolomics and Transcriptional Co-Expression Network Markers to Predict Prognosis of Non-Small Cell Lung Cancer Patients., PMID:36615660

Transcriptome Analysis of Breast Muscle Reveals Pathways Related to Protein Deposition in High Feed Efficiency of Native Turkeys., PMID:35625086

β Cell-specific deletion of Zfp148 improves nutrient-stimulated β cell Ca2+ responses., PMID:35603790

Suppression of nuclear GSK3 signaling promotes serine/one-carbon metabolism and confers metabolic vulnerability in lung cancer cells., PMID:35594343

Identification of zinc-chelating pumpkin seed (Cucurbita pepo L.) peptides and in vitro transport of peptide-zinc chelates., PMID:35340027

The Integration of Metabolomic and Proteomic Analyses Revealed Alterations in Inflammatory-Related Protein Metabolites in Endothelial Progenitor Cells Subjected to Oscillatory Shear Stress., PMID:35250628

Ailanthone Inhibits Proliferation, Migration and Invasion of Osteosarcoma Cells by Downregulating the Serine Biosynthetic Pathway., PMID:35186770

ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction., PMID:34551291

Optimized protocols for ChIP-seq and deletion mutant construction in Pseudomonas syringae., PMID:34485942

Regulation of Gene Expression by Amino Acids in Animal Cells., PMID:34251635

Targeting Serine in Cancer: Is Two Better Than One?, PMID:34219053

RNA sequencing-based analysis of the magnum tissues revealed the novel genes and biological pathways involved in the egg-white formation in the laying hen., PMID:33932994

Effect of Enzymatic Hydrolysis on the Zinc Binding Capacity and in vitro Gastrointestinal Stability of Peptides Derived From Pumpkin (Cucurbita pepo L.) Seeds., PMID:33869265

PSPH promotes melanoma growth and metastasis by metabolic deregulation-mediated transcriptional activation of NR4A1., PMID:33674745

Plantaginis Semen polysaccharides ameliorate renal damage through regulating NLRP3 inflammasome in gouty nephropathy rats., PMID:33624653

Bone metastatic breast cancer cells display downregulation of PKC-ζ with enhanced glutamine metabolism., PMID:33444686

Targeting p300/CBP Attenuates Hepatocellular Carcinoma Progression through Epigenetic Regulation of Metabolism., PMID:33361394

Transcriptome assisted label free proteomics of hepatic tissue in response to both dietary restriction and compensatory growth in cattle., PMID:33217582

Immunostimulatory Effects of Polysaccharides from Spirulina platensis In Vivo and Vitro and Their Activation Mechanism on RAW246.7 Macrophages., PMID:33126624

PSPH induces cell autophagy and promotes cell proliferation and invasion in the hepatocellular carcinoma cell line Huh7 via the AMPK/mTOR/ULK1 signaling pathway., PMID:33079432

Anti-oncogene PTPN13 inactivation by hepatitis B virus X protein counteracts IGF2BP1 to promote hepatocellular carcinoma progression., PMID:33051595

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

Contact Information

Order: order@antibodysystem.com

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For research use only. Not for human or drug use.

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Recombinant Human PSPH Protein, N-His [YHF64301]
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