Catalog No.
YVV22101
Expression system
E. coli
Species
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Protein length
Met1-Thr38
Predicted molecular weight
31.23 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A0A7D6CAT9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ORF10
Induction of the Inflammasome by the SARS-CoV-2 Accessory Protein ORF9b, Abrogated by Small-Molecule ORF9b Homodimerization Inhibitors., PMID:39902616
Cell invasive amyloid assemblies from SARS-CoV-2 peptides can form multiple polymorphs with varying neurotoxicity., PMID:39363846
SARS-CoV-2 ORF10 hijacking ubiquitination machinery reveals potential unique drug targeting sites., PMID:39309499
T-Cell Epitope Mapping of SARS-CoV-2 Reveals Coordinated IFN-γ Production and Clonal Expansion of T Cells Facilitates Recovery from COVID-19., PMID:39066169
Metabolic and mitochondria alterations induced by SARS-CoV-2 accessory proteins ORF3a, ORF9b, ORF9c and ORF10., PMID:38949191
Investigating SARS-CoV-2 virus-host interactions and mRNA expression: Insights using three models of D. melanogaster., PMID:38925484
Involvement of SARS-CoV-2 accessory proteins in immunopathogenesis., PMID:38837257
SARS-CoV-2 mitochondrial metabolic and epigenomic reprogramming in COVID-19., PMID:38614374
SARS-CoV-2 and UPS with potentials for therapeutic interventions., PMID:38490508
Analysis of SARS-CoV-2 genome evolutionary patterns., PMID:38197644
An ncRNA transcriptomics-based approach to design siRNA molecules against SARS-CoV-2 double membrane vesicle formation and accessory genes., PMID:38087193
SARS-CoV-2 Orphan Gene ORF10 Contributes to More Severe COVID-19 Disease., PMID:38076862
Investigation of the individual genetic evolution of SARS-CoV-2 in a small cluster during the rapid spread of the BF.5 lineage in Tokyo, Japan., PMID:37744926
Profiling of SARS-CoV-2 neutralizing antibody-associated antigenic peptides signature using proteome microarray., PMID:37667740
A viral pan-end RNA element and host complex define a SARS-CoV-2 regulon., PMID:37296097
In Silico Analysis of SARS-CoV-2 Spike Proteins of Different Field Variants., PMID:37112648
Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes., PMID:36806058
Immune profiling of SARS-CoV-2 epitopes in asymptomatic and symptomatic pediatric and adult patients., PMID:36788606
Prolonged SARS-CoV-2 Infection and Intra-Patient Viral Evolution in an Immunodeficient Child., PMID:36728777
Novel neutralizing chicken IgY antibodies targeting 17 potent conserved peptides identified by SARS-CoV-2 proteome microarray, and future prospects., PMID:36618358
In silico prediction of the animal susceptibility and virtual screening of natural compounds against SARS-CoV-2: Molecular dynamics simulation based analysis., PMID:36110222
Roles and functions of SARS-CoV-2 proteins in host immune evasion., PMID:36003396
Characterization and Structural Prediction of Proteins in SARS-CoV-2 Bangladeshi Variant Through Bioinformatics., PMID:35966939
Computational Structural and Functional Analyses of ORF10 in Novel Coronavirus SARS-CoV-2 Variants to Understand Evolutionary Dynamics., PMID:35909986
A comprehensive genomic study, mutation screening, phylogenetic and statistical analysis of SARS-CoV-2 and its variant omicron among different countries., PMID:35839568
SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy., PMID:35765167
A close shave: How SARS-CoV-2 induces the loss of cilia., PMID:35695891
SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2ZYG11B activity., PMID:35674692
Structural insights into ORF10 recognition by ZYG11B., PMID:35636250
Spectral and theoretical study of SARS-CoV-2 ORF10 protein interaction with endogenous and exogenous macroheterocyclic compounds., PMID:35617836
Geographical distribution of SARS-CoV-2 amino acids mutations and the concomitant evolution of seven distinct clades in non-human hosts., PMID:35614572
Effect of cannabidiol on apoptosis and cellular interferon and interferon-stimulated gene responses to the SARS-CoV-2 genes ORF8, ORF10 and M protein., PMID:35568225
ORF9c and ORF10 as accessory proteins of SARS-CoV-2 in immune evasion., PMID:35361899
Profiling of SARS-CoV-2 Subgenomic RNAs in Clinical Specimens., PMID:35311586
The importance of accessory protein variants in the pathogenicity of SARS-CoV-2., PMID:35085577
SARS-CoV-2 infection enhances mitochondrial PTP complex activity to perturb cardiac energetics., PMID:35005527
Target genes used for biosensor development in COVID-19 diagnosis., PMID:34974265
Comparative mutational analysis of SARS-CoV-2 isolates from Pakistan and structural-functional implications using computational modelling and simulation approaches., PMID:34968862
A Conservative Replacement in the Transmembrane Domain of SARS-CoV-2 ORF7a as a Putative Risk Factor in COVID-19., PMID:34943191
Emergence, evolution, and vaccine production approaches of SARS-CoV-2 virus: Benefits of getting vaccinated and common questions., PMID:34924802
Emergence of unique SARS-CoV-2 ORF10 variants and their impact on protein structure and function., PMID:34863825
Amantadine has potential for the treatment of COVID-19 because it inhibits known and novel ion channels encoded by SARS-CoV-2., PMID:34853399
SARS-CoV-2 ORF10 suppresses the antiviral innate immune response by degrading MAVS through mitophagy., PMID:34845370
Establishment of a Rapid Detection System for ISG20-Dependent SARS-CoV-2 Subreplicon RNA Degradation Induced by Interferon-α., PMID:34769072
Interactome of human and SARS-CoV-2 proteins to identify human hub proteins associated with comorbidities., PMID:34655901
An in-depth in silico and immunoinformatics approach for designing a potential multi-epitope construct for the effective development of vaccine to combat against SARS-CoV-2 encompassing variants of concern and interest., PMID:34352457
Production of Proteins of the SARS-CoV-2 Proteome for Drug Discovery., PMID:34337272
SARS-CoV-2 Accessory Proteins in Viral Pathogenesis: Knowns and Unknowns., PMID:34305949
In silico analysis of the aggregation propensity of the SARS-CoV-2 proteome: Insight into possible cellular pathologies., PMID:34237472
Transcriptional and epi-transcriptional dynamics of SARS-CoV-2 during cellular infection., PMID:33961822