Catalog No.
YVV22201
Expression system
E. coli
Species
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Protein length
Met1-Lys97
Predicted molecular weight
12.96 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P0DTD2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ORF9b protein, ORF9b, Accessory protein 9b, ORF-9b, Protein 9b, 9b
Coupled equilibria of dimerization and lipid binding modulate SARS Cov 2 Orf9b interactions and interferon response., PMID:40027672
SARS-CoV-2 enhances complement-mediated endothelial injury via the suppression of membrane complement regulatory proteins., PMID:39945674
Induction of the Inflammasome by the SARS-CoV-2 Accessory Protein ORF9b, Abrogated by Small-Molecule ORF9b Homodimerization Inhibitors., PMID:39902616
Pressure to evade cell-autonomous innate sensing reveals interplay between mitophagy, IFN signaling, and SARS-CoV-2 evolution., PMID:39708319
SARS-COV-2 ORF9b Dysregulate Fibrinogen and Albumin Genes in a Liver Cell Line., PMID:39582820
Mouse hepatitis virus JHMV I protein is required for maximal virulence., PMID:39158347
In silico screening and evaluation of antiviral peptides as inhibitors against ORF9b protein of SARS-CoV-2., PMID:39118822
SARS-CoV-2-derived protein Orf9b enhances MARK2 activity via interaction with the autoinhibitory KA1 domain., PMID:38969617
Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant., PMID:38961765
Metabolic and mitochondria alterations induced by SARS-CoV-2 accessory proteins ORF3a, ORF9b, ORF9c and ORF10., PMID:38949191
A Cullin 5-based complex serves as an essential modulator of ORF9b stability in SARS-CoV-2 replication., PMID:38937432
Involvement of SARS-CoV-2 accessory proteins in immunopathogenesis., PMID:38837257
Multiple E3 ligases act as antiviral factors against SARS-CoV-2 via inducing the ubiquitination and degradation of ORF9b., PMID:38709105
Upping the ante: enhanced expression of interferon-antagonizing ORF6 and ORF9b proteins by SARS-CoV-2 variants of concern., PMID:38518551
SARS-CoV-2 and UPS with potentials for therapeutic interventions., PMID:38490508
NYC metropolitan wastewater reveals links between SARS-CoV-2 amino acid mutations and disease outcomes., PMID:37914132
A cell-penetrating peptide derived from SARS-CoV-2 protein Orf9b allosterically inhibits MARK4 activity and mitigates tau toxicity., PMID:37884211
SARS-CoV-2 variants evolve convergent strategies to remodel the host response., PMID:37738970
The Orf9b protein of SARS-CoV-2 modulates mitochondrial protein biogenesis., PMID:37682539
Polypharmacology guided drug repositioning approach for SARS-CoV2., PMID:37556478
SARS-CoV-2 accessory proteins involvement in inflammatory and profibrotic processes through IL11 signaling., PMID:37545510
A Noncoding A-to-U Kozak Site Change Related to the High Transmissibility of Alpha, Delta, and Omicron VOCs., PMID:37341536
Prolonged infective SARS-CoV-2 omicron variant shedding in a patient with diffuse large B cell lymphoma successfully cleared after three courses of remdesivir., PMID:37182841
Ectopic expression of SARS-CoV-2 S and ORF-9B proteins alters metabolic profiles and impairs contractile function in cardiomyocytes., PMID:36910162
Global landscape of SARS-CoV-2 mutations and conserved regions., PMID:36841805
Characterization of SARS-CoV-2 omicron variants from Iran and evaluation of the effect of mutations on the spike, nucleocapsid, ORF8, and ORF9b proteins function., PMID:36576175
Determination of binding affinity of tunicamycin with SARS-CoV-2 proteins: Proteinase, protease, nsp2, nsp9, ORF3a, ORF7a, ORF8, ORF9b, envelope and RBD of spike glycoprotein., PMID:36349218
Pathophysiological involvement of host mitochondria in SARS-CoV-2 infection that causes COVID-19: a comprehensive evidential insight., PMID:36308668
The role of SARS-CoV-2 accessory proteins in immune evasion., PMID:36265309
NSP4 and ORF9b of SARS-CoV-2 Induce Pro-Inflammatory Mitochondrial DNA Release in Inner Membrane-Derived Vesicles., PMID:36230930
Structural characterization of SARS-CoV-2 dimeric ORF9b reveals potential fold-switching trigger mechanism., PMID:36184694
Roles and functions of SARS-CoV-2 proteins in host immune evasion., PMID:36003396
Structural basis for Sarbecovirus ORF6 mediated blockage of nucleocytoplasmic transport., PMID:35970938
Unique mutations in SARS-CoV-2 Omicron subvariants' non-spike proteins: Potential impacts on viral pathogenesis and host immune evasion., PMID:35944840
Simultaneous monitoring of eight human respiratory viruses including SARS-CoV-2 using liquid chromatography-tandem mass spectrometry., PMID:35927299
Variations of SARS-CoV-2 in the Iranian population and candidate putative drug-like compounds to inhibit the mutated proteins., PMID:35847618
Altered subgenomic RNA abundance provides unique insight into SARS-CoV-2 B.1.1.7/Alpha variant infections., PMID:35790808
Genomic Epidemiology of Imported Cases of COVID-19 in Guangdong Province, China, October 2020 - May 2021., PMID:35676810
Binding of SARS-CoV-2 protein ORF9b to mitochondrial translocase TOM70 prevents its interaction with chaperone HSP90., PMID:35643212
The Deubiquitinase USP29 Promotes SARS-CoV-2 Virulence by Preventing Proteasome Degradation of ORF9b., PMID:35638730
The SARS-CoV2 and mitochondria: the impact on cell fate., PMID:35546040
Collection of Monoclonal Antibodies Targeting SARS-CoV-2 Proteins., PMID:35216036
Anti-SARS-CoV-2 IgG responses are powerful predicting signatures for the outcome of COVID-19 patients., PMID:35116173
Target genes used for biosensor development in COVID-19 diagnosis., PMID:34974265
Evolution of enhanced innate immune evasion by SARS-CoV-2., PMID:34942634
ORF8/ORF8a: a difference between SARS-CoV-2 and SARS-CoV., PMID:34887330
Phosphorylation of SARS-CoV-2 Orf9b Regulates Its Targeting to Two Binding Sites in TOM70 and Recruitment of Hsp90., PMID:34502139
Revelation of Potent Epitopes Present in Unannotated ORF Antigens of SARS-CoV-2 for Epitope-Based Polyvalent Vaccine Design Using Immunoinformatics Approach., PMID:34497604
Homology between SARS CoV-2 and human proteins., PMID:34433832
The MAVS Immune Recognition Pathway in Viral Infection and Sepsis., PMID:34348482
For research use only. Not for human or drug use.
