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Recombinant Human TFAP4 Protein, N-His

Catalog #:   YHF88601 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: Q01664
Protein length: Met1-Ala192
Overview

Catalog No.

YHF88601

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Met1-Ala192

Predicted molecular weight

24.73 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q01664

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Activating enhancer-binding protein 4, bHLHc41, Class C basic helix-loop-helix protein 41, BHLHC41, TFAP4, Transcription factor AP-4

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human TFAP4 Protein
References

Genetic Associations of ACOX2 Gene with Milk Yield and Composition Traits in Chinese Holstein Cows., PMID:40218347

The development of pyridazinone-based andrographolide derivatives as anti-cancer agents with the ability of inhibiting the TFAP4/Wnt/β-catenin signaling pathway., PMID:40215943

Genome-wide CRISPR screen identifies IRF1 and TFAP4 as transcriptional regulators of Galectin-9 in T cell acute lymphoblastic leukemia., PMID:40106574

TFAP4 Regulation of MCM5 Activates the PI3K/AKT Pathway to Promote Invasion and Metastasis of Gastric Cancer., PMID:39971831

In silico analysis of lncRNA-miRNA-mRNA signatures related to Sorafenib effectiveness in liver cancer cells., PMID:39839902

TFAP4 regulates the progression of liver fibrosis through the STING signaling pathway., PMID:39827671

circ_0006988 promotes gastric cancer cell proliferation, migration and invasion through miRNA-92a-2-5p/TFAP4 axis., PMID:39400106

USP15, activated by TFAP4 transcriptionally, stabilizes SHC1 via deubiquitination and deteriorates renal cell carcinoma., PMID:38847328

Ubiquitin-specific peptidase 15 regulates the TFAP4/PCGF1 axis facilitating liver metastasis of colorectal cancer and cell stemness., PMID:38801926

Predictive value of immediate early response 5 like (IER5L) in the prognosis and immune checkpoint blockade therapy of non-small cell lung cancer patients., PMID:38552564

Chromatin profiling reveals TFAP4 as a critical transcriptional regulator of bovine satellite cell differentiation., PMID:38475725

Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation., PMID:37995683

Squalene epoxidase/SQLE is a candidate target for treatment of colorectal cancers with p53 mutation and elevated c-MYC expression., PMID:37705742

Downregulation of miR-144 blocked the proliferation and invasion of nerve cells in Hirschsprung disease by regulating Transcription Factor AP 4 (TFAP4)., PMID:37610449

TFAP4 promotes the progression of liver fibrosis through regulating double-negative T cell differentiation via OX40., PMID:37060810

Targeting NK-1R attenuates renal fibrosis via modulating inflammatory responses and cell fate in chronic kidney disease., PMID:37033943

Conserved Molecular Players Involved in Human Nose Morphogenesis Underlie Evolution of the Exaggerated Snout Phenotype in Cichlids., PMID:36930462

Deletion of the transcriptional regulator TFAP4 accelerates c-MYC-driven lymphomagenesis., PMID:36894688

Identification of a novel senescence-associated signature to predict biochemical recurrence and immune microenvironment for prostate cancer., PMID:36891298

Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer., PMID:36548402

Global and precise identification of functional miRNA targets in mESCs by integrative analysis., PMID:35899551

AP4 suppresses DNA damage, chromosomal instability and senescence via inducing MDC1/Mediator of DNA damage Checkpoint 1 and repressing MIR22HG/miR-22-3p., PMID:35624466

Cucurbitacin E Triggers Cellular Senescence in Colon Cancer Cells via Regulating the miR-371b-5p/TFAP4 Signaling Pathway., PMID:35192356

Inhibitory effect of CC chemokine ligand 23 (CCL23)/ transcription factor activating enhancer binding protein 4 (TFAP4) on cell proliferation, invasion and angiogenesis in hepatocellular carcinoma., PMID:35001801

Potential Molecular Mechanisms and Remdesivir Treatment for Acute Respiratory Syndrome Corona Virus 2 Infection/COVID 19 Through RNA Sequencing and Bioinformatics Analysis., PMID:34992355

Upregulating microRNA-373-3p promotes apoptosis and inhibits metastasis of hepatocellular carcinoma cells., PMID:34983307

TFAP4 promotes the growth of prostate cancer cells by upregulating FOXK1., PMID:34630654

A novel variant in DYNC1H1 could contribute to human amyotrophic lateral sclerosis-frontotemporal dementia spectrum., PMID:34535505

Unexpected suppression of tumorigenesis by c-MYC via TFAP4-dependent restriction of stemness in B lymphocytes., PMID:34283887

Silencing of the Long Non-Coding RNA TTN-AS1 Attenuates the Malignant Progression of Osteosarcoma Cells by Regulating the miR-16-1-3p/TFAP4 Axis., PMID:34141611

Corrigendum: MicroRNA-608 Promotes Apoptosis in Non-Small Cell Lung Cancer Cells Treated With Doxorubicin Through the Inhibition of TFAP4., PMID:33859675

MicroRNA-124 suppresses the invasion and proliferation of breast cancer cells by targeting TFAP4., PMID:33717268

Transcription Factor AP4 Mediates Cell Fate Decisions: To Divide, Age, or Die., PMID:33567514

Expression of MiR-608 in Nonsmall Cell Lung Cancer and Molecular Mechanism of Apoptosis and Migration of A549 Cells., PMID:33426072

An integrated pan-cancer analysis of TFAP4 aberrations and the potential clinical implications for cancer immunity., PMID:33373169

HLH-11 modulates lipid metabolism in response to nutrient availability., PMID:33235199

Cucurbitacin E Chemosensitizes Colorectal Cancer Cells via Mitigating TFAP4/Wnt/β-Catenin Signaling., PMID:33205649

Identification of a dynamic gene regulatory network required for pluripotency factor-induced reprogramming of mouse fibroblasts and hepatocytes., PMID:33034061

Screening of potential genes and transcription factors involved in post-radiation cognitive dysfunction in mice via bioinformatics., PMID:35117246

Transcription factor AP-4 (TFAP4)-upstream ORF coding 66 aa inhibits the malignant behaviors of glioma cells by suppressing the TFAP4/long noncoding RNA 00520/microRNA-520f-3p feedback loop., PMID:31943575

MicroRNA-608 Promotes Apoptosis in Non-Small Cell Lung Cancer Cells Treated With Doxorubicin Through the Inhibition of TFAP4., PMID:31552102

The polymorphic variant rs1800734 influences methylation acquisition and allele-specific TFAP4 binding in the MLH1 promoter leading to differential mRNA expression., PMID:31530880

TFAP4 Promotes Hepatocellular Carcinoma Invasion and Metastasis via Activating the PI3K/AKT Signaling Pathway., PMID:31281549

Soluble Heparin Binding Epidermal Growth Factor-Like Growth Factor Is a Regulator of GALGT2 Expression and GALGT2-Dependent Muscle and Neuromuscular Phenotypes., PMID:31036568

Ap4 is rate limiting for intestinal tumor formation by controlling the homeostasis of intestinal stem cells., PMID:30177706

Transcription factor AP-4 promotes tumorigenic capability and activates the Wnt/β-catenin pathway in hepatocellular carcinoma., PMID:30026867

MicroRNA-302c represses epithelial-mesenchymal transition and metastasis by targeting transcription factor AP-4 in colorectal cancer., PMID:29906744

Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma., PMID:29880876

Elevated TFAP4 regulates lncRNA TRERNA1 to promote cell migration and invasion in gastric cancer., PMID:29845218

Overexpression of transcription factor activating enhancer binding protein 4 (TFAP4) predicts poor prognosis for colorectal cancer patients., PMID:28912857

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human TFAP4 Protein, N-His [YHF88601]
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