Catalog No.
DVV08601
Expression system
Mammalian Cells
Species reactivity
Hepatitis C Virus (HCV)
Host species
Human
Isotype
IgG1-kappa
Clonality
Monoclonal
Target
NS1, gp68, gp70, Envelope glycoprotein E2, Genome polyprotein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P27958
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
MBL-HCV1, MBL HCV1
Clone ID
MBL-HCV1
HCV Proteins Modulate the Host Cell miRNA Expression Contributing to Hepatitis C Pathogenesis and Hepatocellular Carcinoma Development. PMID: 34069740
Expression of MBP-HCV NS1/E2 fusion protein in E. coli and detection of anti-NS1/E2 antibody in type C chronic liver disease. PMID: 1314578
Expression of HCV E2/NS1 protein as a fusion protein with maltose binding protein: detection of anti-E2/NS1 antibody in chronic liver disease. PMID: 7686121
Roles of secretory glycoproteins in particle formation of Flaviviridae viruses. PMID: 31342548
Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins. PMID: 1846505
[Hepatitis C]. PMID: 8345654
Hepatitis C and liver transplantation. PMID: 8527717
Degree and distribution of variability in the 5' untranslated, E1, E2/NS1 and NS5 regions of the hepatitis C virus (HCV). PMID: 9751009
Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins. PMID: 28991176
Antibody response to E2/NS1 hepatitis C virus protein in patients with acute hepatitis C. PMID: 9076628
Viral Interference Between Dengue Virus and Hepatitis C Virus Infections. PMID: 32875000
[Hepatitis C immunology]. PMID: 10614142
Secretion and purification of hepatitis C virus NS1 glycoprotein produced by recombinant baculovirus-infected insect cells. PMID: 7686870
Significance of anti-E2 in the diagnosis of HCV infection in patients on maintenance hemodialysis: anti-E2 is frequently detected among anti-HCV antibody-negative patients. PMID: 8959633
Viral loads and E2/NS1 region sequences of hepatitis C virus in hepatocellular carcinoma and surrounding liver. PMID: 9159034
Host-derived apolipoproteins play comparable roles with viral secretory proteins Erns and NS1 in the infectious particle formation of Flaviviridae. PMID: 28644867
Expression and purification of E2/NS1 protein of hepatitis C virus and detection of anti-E2/NS1 antibodies in chronic liver disease patients. PMID: 12595764
Expression of the amino-terminal half of the NS1 region of the hepatitis C virus genome and detection of an antibody to the expressed protein in patients with liver diseases. PMID: 1379627
Syntheses of immunodominant peptide regions of hepatitis C viral pathogens using PS-BDODMA resin: a single peptide derived from the conserved domain (E2/NS1) was highly effective in detecting anti-HCV antibodies. PMID: 11168897
[Evolution of hepatitis C virus (HCV) viremia and adaptation of HCV in persistent infection in patients with acute hepatitis]. PMID: 7521430
[Significance of polypeptide antigen of HCVE2/NS1 relative conservation region in detection of anti-HCV]. PMID: 12759957
Natural history of hepatitis C. PMID: 7529217
Epidemiological studies on hepatitis C virus infection: detection, prevalence, exposure and prevention. PMID: 7814243
Development and Evaluation of a Universal and Supersensitive NS1-Based Luciferase Immunosorbent Assay to Detect Zika Virus-Specific IgG. PMID: 31552611
Structure, genomic organization, replication and variability of hepatitis C virus. PMID: 8918741
Sequence uniqueness and sequence variability as modulating factors of human anti-HCV humoral immune response. PMID: 18256830
[Fundamental studies of hepatitis C virus: a review]. PMID: 1331574
Genomic typing of hepatitis C viruses from Korean patients: implications of genome variation in the E2/NS1 region. PMID: 8240354
Partial nucleotide sequence analysis of a French hepatitis C virus: implications for HCV genetic variability in the E2/NS1 protein. PMID: 1655961
Expression of structural proteins of hepatitis C virus (HCV) in mammalian cells. PMID: 18726270
Translation-competent 48S complex formation on HCV IRES requires the RNA-binding protein NSAP1. PMID: 21715376
[Genomic changes in the E2/NS1 region of HCV before and after IFN therapy in relation to clinical course]. PMID: 7521410
Use of a novel hepatitis C virus (HCV) major-epitope chimeric polypeptide for diagnosis of HCV infection. PMID: 10203493
Hepatitis C transmission between spouses. PMID: 8985816
[Genomic changes in the E2/NS1 region of HCV before and after IFN therapy]. PMID: 7563902
[Innate immune responses against viral infection and its suppression by viral proteins]. PMID: 23449408
Hypervariable 5'-terminus of hepatitis C virus E2/NS1 encodes antigenically distinct variants. PMID: 7689636
Variability of the E2/NS1 region of Swedish hepatitis C virus strains and its correlation to genotypes. PMID: 7939424
A novel antigen detection immunoassay for field diagnosis of hepatitis C virus infection. PMID: 14677657
Analysis of hepatitis C virus capsid, E1, and E2/NS1 proteins expressed in insect cells. PMID: 8212557
Comparison between homologies of E2/NS1 gene from genotype III Chinese isolates of hepatitis C virus and that from reported isolates. PMID: 11155671
Confirmation of hepatitis C infection: a comparison of five immunoblot assays. PMID: 7519796
[Molecular genotypes of hepatitis C virus and their divergence times]. PMID: 8385234
Low-level hepatitis C viremia and humoral immune response to NS4 in chronic hepatitis B virus-hepatitis C virus coinfection. PMID: 15513365
Hepatitis C virus-related proteins in kidney tissue from hepatitis C virus-infected patients with cryoglobulinemic membranoproliferative glomerulonephritis. PMID: 9141444
Hepatitis C virus transmission in a pediatric oncology ward: analysis of an outbreak and review of the literature. PMID: 11310819
Human monoclonal antibody MBL-HCV1 delays HCV viral rebound following liver transplantation: a randomized controlled study. PMID: 23356386
Prevention of allograft HCV recurrence with peri-transplant human monoclonal antibody MBL-HCV1 combined with a single oral direct-acting antiviral: A proof-of-concept study. PMID: 28127942
High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody. PMID: 24956119