Please ensure Javascript is enabled for purposes of website accessibility
Home / Products / Research Biosimilar

Research Grade Anti-Ganglioside GD3 (PF-06688992)

Catalog #:   DHK11301 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHK11301

Expression system

Mammalian Cells

Species reactivity

General

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Target

Ganglioside GD3

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

PubChem CID: 20057323

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

PF-06688992, PF 06688992, PF06688992

Clone ID

PF-06688992

Data Image
References

Action Mechanisms of Exosomes Derived from GD3/GD2-Positive Glioma Cells in the Regulation of Phenotypes and Intracellular Signaling: Roles of Integrins., PMID:39684463

A case of variant of GBS with positive serum ganglioside GD3 IgG antibody., PMID:38831339

Effect of Oral β-Glucan on Antibody Response to Ganglioside Vaccine in Patients With High-Risk Neuroblastoma: A Phase 2 Randomized Clinical Trial., PMID:36547975

Phosphacan acts as a repulsive cue in murine and rat cerebellar granule cells in a TAG-1/GD3 rafts-dependent manner., PMID:36227633

Using a combination of gangliosides and cell surface vimentin as surface biomarkers for isolating osteosarcoma cells in microfluidic devices., PMID:33912384

Survival Impact of Anti-GD2 Antibody Response in a Phase II Ganglioside Vaccine Trial Among Patients With High-Risk Neuroblastoma With Prior Disease Progression., PMID:33326254

Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs., PMID:33034545

Ganglioside GD3 regulates dendritic growth in newborn neurons in adult mouse hippocampus via modulation of mitochondrial dynamics., PMID:32743804

Lipid Rafts from Olfactory Ensheathing Cells: Molecular Composition and Possible Roles., PMID:32415577

Exosomes Represent an Immune Suppressive T Cell Checkpoint in Human Chronic Inflammatory Microenvironments., PMID:32299258

[Guillain-Barré syndrome with refractory optic neuropathy]., PMID:31564705

Vaccination with Tumor-Ganglioside Glycomimetics Activates a Selective Immunity that Affords Cancer Therapy., PMID:31105061

Tumor-Associated Disialylated Glycosphingolipid Antigen-Revealing Antibodies Found in Melanoma Patients' Immunoglobulin Repertoire Suggest a Two-Direction Regulation Mechanism Between Immune B Cells and the Tumor., PMID:31024530

Chemical Synthesis and Evaluation of a Disialic Acid-Containing Dextran Polymer as an Inhibitor for the Interaction between Siglec 7 and Its Ligand., PMID:28374980

Synthesis of an S-Linked α(2→8) GD3 Antigen and Evaluation of the Immunogenicity of Its Glycoconjugate., PMID:28295752

Monosialyl Ganglioside GM3 Decreases Apolipoprotein B-100 Secretion in Liver Cells., PMID:28019668

Acute bulbar palsy without ophtalmoplegia associated with anti-GD3 IgM antibodies., PMID:27837367

[A case of severe chronic inflammatory demyelinating polyradiculoneuropathy with monoclonal gammopathy of undetermined significance with alternating immunoglobulin class to IgM from IgA]., PMID:27580763

Oncotargets GD2 and GD3 are highly expressed in sarcomas of children, adolescents, and young adults., PMID:27304202

Neogenin, Defined as a GD3-associated Molecule by Enzyme-mediated Activation of Radical Sources, Confers Malignant Properties via Intracytoplasmic Domain in Melanoma Cells., PMID:27288875

Glycolipid GD3 and GD3 synthase are key drivers for glioblastoma stem cells and tumorigenicity., PMID:27143722

Dual targeting NG2 and GD3A using Mab-Zap immunotoxin results in reduced glioma cell viability in vitro., PMID:25550537

Interaction of ganglioside GD3 with an EGF receptor sustains the self-renewal ability of mouse neural stem cells in vitro., PMID:24198336

Natural Antibodies Against Sialoglycans., PMID:24037491

Accelerated tumor growth mediated by sublytic levels of antibody-induced complement activation is associated with activation of the PI3K/AKT survival pathway., PMID:23833306

Positioning ganglioside D3 as an immunotherapeutic target in lymphangioleiomyomatosis., PMID:23665200

The effects of age and ganglioside composition on the rate of motor nerve terminal regeneration following antibody-mediated injury in mice., PMID:23401234

Targeted delivery of immunotoxin by antibody to ganglioside GD3: a novel drug delivery route for tumor cells., PMID:23383146

Involvement of gangliosides in the process of Cbp/PAG phosphorylation by Lyn in developing cerebellar growth cones., PMID:23035659

Proteomic analysis of ganglioside-associated membrane molecules: substantial basis for molecular clustering., PMID:22936677

Neuroblast migration and P2Y(1) receptor mediated calcium signalling depend on 9-O-acetyl GD3 ganglioside., PMID:22894715

Altered ganglioside GD3 in HeLa cells might influence the cytotoxic abilities of NK cells., PMID:22795094

Fine specificity and cross-reactions of monoclonal antibodies to group B streptococcal capsular polysaccharide type III., PMID:22634296

Small-molecule inhibitors of NMO-IgG binding to aquaporin-4 reduce astrocyte cytotoxicity in neuromyelitis optica., PMID:22319008

Changes in glycosphingolipid composition during differentiation of human embryonic stem cells to ectodermal or endodermal lineages., PMID:21956927

9-O-Acetyl GD3 in lymphoid and erythroid cells., PMID:21618115

Expression of GD2 and GD3 gangliosides in human embryonic neural stem cells., PMID:21395555

Ganglioside GD3 monoclonal antibody-induced paxillin tyrosine phosphorylation and filamentous actin assembly in cerebellar growth cones., PMID:21214573

The idiotype (Id) cascade in mice elicited the production of anti-R24 Id and anti-anti-Id monoclonal antibodies with antitumor and protective activity against human melanoma., PMID:21070480

Anti-GD3 chimeric sFv-CD28/T-cell receptor zeta designer T cells for treatment of metastatic melanoma and other neuroectodermal tumors., PMID:20460472

Preclinical evaluation of the synthetic adjuvant SQS-21 and its constituent isomeric saponins., PMID:20450868

Development of a novel therapy for Lipo-oligosaccharide-induced experimental neuritis: use of peptide glycomimics., PMID:20132479

Novel anti-idiotype antibody therapy for lipooligosaccharide-induced experimental autoimmune neuritis: use relevant to Guillain-Barré syndrome., PMID:20077429

Detection of GD3 ganglioside in primary melanomas depends on histopathologic procedures used for tumor preservation., PMID:19818222

Characterization of GD3 ganglioside as a novel biomarker of mouse neural stem cells., PMID:19776077

Sialic acids as regulators of molecular and cellular interactions., PMID:19699080

Streptococcus mitis phage-encoded adhesins mediate attachment to {alpha}2-8-linked sialic acid residues on platelet membrane gangliosides., PMID:19506011

The first extracellular domain of the tumour stem cell marker CD133 contains an antigenic ganglioside-binding motif., PMID:19216024

Complex gangliosides are apically sorted in polarized MDCK cells and internalized by clathrin-independent endocytosis., PMID:19021775

Synthesis of QS-21-xylose: establishment of the immunopotentiating activity of synthetic QS-21 adjuvant with a melanoma vaccine., PMID:18624313

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

Need help with your order?

Find out more about placing an order here

Research Grade Anti-Ganglioside GD3 (PF-06688992) [DHK11301]
Terms of sale Website terms of use Cookie policy Privacy
Copyright © 2025 AntibodySystem SAS. All Rights Reserved.            All Products are for Research Use Only