Catalog No.
RHK33701
Species reactivity
Human
Host species
Human
Isotype
VHH-hFc
Clonality
Monoclonal
Target
LTRPC4, Transient receptor potential cation channel subfamily M member 4, TRPM4, Melastatin-4, LTrpC-4, hTRPM4, Calcium-activated non-selective cation channel 1, LTrpC4, Long transient receptor potential channel 4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q8TD43
Applications
ELISA, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0760
Development and in vitro characterization of humanized antibodies for blocking human TRPM4 channel., PMID:40473754
Identification of putative baroreceptors in human aortic arch by histological and omics analyses., PMID:40335722
Genomic and Immunologic Correlates in Prostate Cancer with High Expression of KLK2., PMID:38396898
In vivo evaluation of monoclonal antibody M4M using a humanised rat model of stroke demonstrates attenuation of reperfusion injury via blocking human TRPM4 channel., PMID:38345028
TRPM4 blocking antibody reduces neuronal excitotoxicity by specifically inhibiting glutamate-induced calcium influx under chronic hypoxia., PMID:38199274
Two Transient Receptor Potential Channels at Focal Adhesions., PMID:37596792
TRPM4 Blocking Antibody Protects Cerebral Vasculature in Delayed Stroke Reperfusion., PMID:37239151
Binding epitope for recognition of human TRPM4 channel by monoclonal antibody M4M., PMID:36380063
Abnormal levels of mitochondrial Ca2+ channel proteins in plasma neuron-derived extracellular vesicles of early schizophrenia., PMID:35867070
Pharmacological Modulation and (Patho)Physiological Roles of TRPM4 Channel-Part 1: Modulation of TRPM4., PMID:35056138
Development and characterization of a monoclonal antibody blocking human TRPM4 channel., PMID:34002002
TRPM4 in Cancer-A New Potential Drug Target., PMID:33562811
HIV-1 Vpr-Induced Proinflammatory Response and Apoptosis Are Mediated through the Sur1-Trpm4 Channel in Astrocytes., PMID:33293383
Comparison of Anti-oncotic Effect of TRPM4 Blocking Antibody in Neuron, Astrocyte and Vascular Endothelial Cell Under Hypoxia., PMID:33195194
SUR1-TRPM4 channels, not KATP, mediate brain swelling following cerebral ischemia., PMID:31899311
TRPM4-specific blocking antibody attenuates reperfusion injury in a rat model of stroke., PMID:31664513
EB1- and EB2-dependent anterograde trafficking of TRPM4 regulates focal adhesion turnover and cell invasion., PMID:31112396
Increased TRPM4 Activity in Cerebral Artery Myocytes Contributes to Cerebral Blood Flow Reduction After Subarachnoid Hemorrhage in Rats., PMID:31073979
Porcine FcεRI Mediates Porcine Reproductive and Respiratory Syndrome Virus Multiplication and Regulates the Inflammatory Reaction., PMID:29761267
Direct versus indirect actions of ghrelin on hypothalamic NPY neurons., PMID:28877214
Single nucleotide polymorphisms and genotypes of transient receptor potential ion channel and acetylcholine receptor genes from isolated B lymphocytes in myalgic encephalomyelitis/chronic fatigue syndrome patients., PMID:27834303
TRPV2 Channels Contribute to Stretch-Activated Cation Currents and Myogenic Constriction in Retinal Arterioles., PMID:27784066
Shear stress activates monovalent cation channel transient receptor potential melastatin subfamily 4 in rat atrial myocytes via type 2 inositol 1,4,5-trisphosphate receptors and Ca(2+) release., PMID:26751048
TRPM4 protein expression in prostate cancer: a novel tissue biomarker associated with risk of biochemical recurrence following radical prostatectomy., PMID:26590985
Functional expression of transient receptor potential channels in human endometrial stromal cells during the luteal phase of the menstrual cycle., PMID:25820697
9-Phenanthrol and flufenamic acid inhibit calcium oscillations in HL-1 mouse cardiomyocytes., PMID:23831210
Transient receptor potential channel m4 and m5 in magnocellular cells in rat supraoptic and paraventricular nuclei., PMID:21848647
Isoform-selective physical coupling of TRPC3 channels to IP3 receptors in smooth muscle cells regulates arterial contractility., PMID:20378853
TRPM4 regulates migration of mast cells in mice., PMID:19046767
Transient receptor potential cation channels in normal and dystrophic mdx muscle., PMID:18504127
Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4., PMID:17293867
For research use only. Not for human or drug use.
