Catalog No.
RVV20801
Species reactivity
Human papillomavirus type (HPV16, HPV18, HPV31, HPV33, HPV35, HPV51, HPV52, HPV58)
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Minor capsid protein L2, L2
Concentration
3.4 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P03107
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
MAb24B
Mutation Profile of HPV16 L1 and L2 Genes in Different Geographic Areas. PMID: 36680181
A Current Update on Human Papillomavirus-Associated Head and Neck Cancers. PMID: 31600915
Integrated genomic and molecular characterization of cervical cancer. PMID: 36214947
Detection of HPV16 viral load in L2 gene as a related predictor of cervical cancer among women in Dhi-Qar province by qRT-PCR. PMID: 36750540
Retraction Note: Detection of HPV16 viral load in L2 gene as a related predictor of cervical cancer among women in Dhi-Qar province by qRT-PCR. PMID: 25972404
Seroepidemiology of Human Papillomavirus 16 (HPV16) L2 and Generation of L2-Specific Human Chimeric Monoclonal Antibodies. PMID: 26925750
HPV16 L2 improves HPV16 L1 gene delivery as an important approach for vaccine design against cervical cancer. PMID: 23762404
Differential expression of HPV16 L2 gene in cervical cancers harboring episomal HPV16 genomes: influence of synonymous and non-coding region variations. PMID: 32510304
Correlation between cervical HPV DNA detection and HPV16 seroreactivity measured with L1-only and L1+L2 viral capsid antigens. PMID: 35763643
Human Papillomavirus Type 16 L2 Gene Sequence Variation Analysis in Indonesian Cervical Cancer Specimens. PMID: 29207600
Host cell transcriptome modification upon exogenous HPV16 L2 protein expression. PMID: 22154072
The high risk HPV16 L2 minor capsid protein has multiple transport signals that mediate its nucleocytoplasmic traffic. PMID: 23689062
L2, the minor capsid protein of papillomavirus. PMID: 24928042
The nuclear retention signal of HPV16 L2 protein is essential for incoming viral genome to transverse the trans-Golgi network. PMID: 35458534
Human Papillomavirus L2 Capsid Protein Stabilizes γ-Secretase during Viral Infection. PMID: 23335178
HPV16 L1 and L2 DNA methylation predicts high-grade cervical intraepithelial neoplasia in women with mildly abnormal cervical cytology. PMID: 34960729
HPV16 Entry into Epithelial Cells: Running a Gauntlet. PMID: 33802456
RG1-VLP and Other L2-Based, Broad-Spectrum HPV Vaccine Candidates. PMID: 35891458
HPV16 Induces Formation of Virus-p62-PML Hybrid Bodies to Enable Infection. PMID: 33568731
High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility. PMID: 27889616
Developments in L2-based human papillomavirus (HPV) vaccines. PMID: 27122588
Furin Cleavage of L2 during Papillomavirus Infection: Minimal Dependence on Cyclophilins. PMID: 19860897
Role of L2 cysteines in papillomavirus infection and neutralization. PMID: 27654294
The Cytoskeletal Adaptor Obscurin-Like 1 Interacts with the Human Papillomavirus 16 (HPV16) Capsid Protein L2 and Is Required for HPV16 Endocytosis. PMID: 35193933
ISA101 and nivolumab for HPV-16+ cancer: updated clinical efficacy and immune correlates of response. PMID: 34516991
Immunological responses and anti-tumor effects of HPV16/18 L1-L2-E7 multiepitope fusion construct along with curcumin and nanocurcumin in C57BL/6 mouse model. PMID: 23388722
The transcription factors TBX2 and TBX3 interact with human papillomavirus 16 (HPV16) L2 and repress the long control region of HPVs. PMID: 28056100
Chimeric L2-Based Virus-Like Particle (VLP) Vaccines Targeting Cutaneous Human Papillomaviruses (HPV). PMID: 17980618
Transient expression of HPV16 E7 peptide (aa 44-60) and HPV16 L2 peptide (aa 108-120) on chimeric potyvirus-like particles using Potato virus X-based vector. PMID: 17239496
A papillomavirus-like particle (VLP) vaccine displaying HPV16 L2 epitopes induces cross-neutralizing antibodies to HPV11. PMID: 22761884
Development of AAVLP(HPV16/31L2) particles as broadly protective HPV vaccine candidate. PMID: 24444361
An L2 SUMO interacting motif is important for PML localization and infection of human papillomavirus type 16. PMID: 14505907
Safety and immunogenicity of a peptide containing the cross-neutralization epitope of HPV16 L2 administered nasally in healthy volunteers. PMID: 26569287
Cleavage of the HPV16 Minor Capsid Protein L2 during Virion Morphogenesis Ablates the Requirement for Cellular Furin during De Novo Infection. PMID: 12560332
Interaction of L2 with beta-actin directs intracellular transport of papillomavirus and infection. PMID: 20684966
Inhibition of nuclear entry of HPV16 pseudovirus-packaged DNA by an anti-HPV16 L2 neutralizing antibody. PMID: 34740725
A respirable HPV-L2 dry-powder vaccine with GLA as amphiphilic lubricant and immune-adjuvant. PMID: 31743367
Glutathione contributes to efficient post-Golgi trafficking of incoming HPV16 genome. PMID: 35608352
Human Papillomavirus Minor Capsid Protein L2 Mediates Intracellular Trafficking into and Passage beyond the Endoplasmic Reticulum. PMID: 17010405
Neutralization of HPV16, 18, 31, and 58 pseudovirions with antisera induced by immunizing rabbits with synthetic peptides representing segments of the HPV16 minor capsid protein L2 surface region. PMID: 21346798
Cross-neutralization potential of native human papillomavirus N-terminal L2 epitopes. PMID: 33238224
Genetic signatures for lineage/sublineage classification of HPV16, 18, 52 and 58 variants. PMID: 19214230
Two highly conserved cysteine residues in HPV16 L2 form an intramolecular disulfide bond and are critical for infectivity in human keratinocytes. PMID: 12610128
Cell surface-binding motifs of L2 that facilitate papillomavirus infection. PMID: 17150135
Serum antibody response to Human papillomavirus (HPV) infections detected by a novel ELISA technique based on denatured recombinant HPV16 L1, L2, E4, E6 and E7 proteins. PMID: 10712890
Human papillomavirus vaccines. PMID: 18508629
HPV-16 RNA processing. PMID: 27518844
Human Papillomavirus Type 16 L2 DNA Methylation in Exfoliated Cervical Cells From College-Age Women. PMID: 36263027
Next generation L2-based HPV vaccines cross-protect against cutaneous papillomavirus infection and tumor development. PMID: 22927980
The S100A10 subunit of the annexin A2 heterotetramer facilitates L2-mediated human papillomavirus infection. PMID: 29212932
Minor Capsid Protein L2 Polytope Induces Broad Protection against Oncogenic and Mucosal Human Papillomaviruses. PMID: 26362430
Capsid display of a conserved human papillomavirus L2 peptide in the adenovirus 5 hexon protein: a candidate prophylactic hpv vaccine approach. PMID: 28463988
Translocation of the papillomavirus L2/vDNA complex across the limiting membrane requires the onset of mitosis. PMID: 36815785
Critical Residues Involved in the Coassembly of L1 and L2 Capsid Proteins of Human Papillomavirus 16. PMID: 27398412
Involvement of Nucleophosmin (NPM1/B23) in Assembly of Infectious HPV16 Capsids. PMID: 15507604
The l2 minor capsid protein of human papillomavirus type 16 interacts with a network of nuclear import receptors. PMID: 11158207
Papillomavirus-like particle vaccines. PMID: 29207511
Subcellular Trafficking of the Papillomavirus Genome during Initial Infection: The Remarkable Abilities of Minor Capsid Protein L2. PMID: 30996086
Phosphorylation of Human Papillomavirus Type 16 L2 Contributes to Efficient Virus Infectious Entry. PMID: 20334659
Papillomavirus pseudovirions packaged with the L2 gene induce cross-neutralizing antibodies. PMID: 11287582
L1 interaction domains of papillomavirus l2 necessary for viral genome encapsidation. PMID: 30926288
Oral immunization with bacteriophage MS2-L2 VLPs protects against oral and genital infection with multiple HPV types associated with head & neck cancers and cervical cancer. PMID: 19368776
Potent anti-HPV immune responses induced by tandem repeats of the HPV16 L2 (20 -- 38) peptide displayed on bacterial thioredoxin. PMID: 27725301
Genomic diversity and phylogenetic relationships of human papillomavirus 16 (HPV16) in Nepal. PMID: 23383218
Optimization of multimeric human papillomavirus L2 vaccines. PMID: 30946955
The endocytic trafficking pathway of oncogenic papillomaviruses. PMID: 29914845
Adenovirus based HPV L2 vaccine induces broad cross-reactive humoral immune responses. PMID: 22351779
Influence of physiologic folate deficiency on human papillomavirus type 16 (HPV16)-harboring human keratinocytes in vitro and in vivo. PMID: 24662712
A three component mix of thioredoxin-L2 antigens elicits broadly neutralizing responses against oncogenic human papillomaviruses. PMID: 18367526
For research use only. Not for human or drug use.
