Catalog No.
VVV20802
Species reactivity
Human papillomavirus type 16
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Minor capsid protein L2, L2
Concentration
1.51 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P03107
Applications
ELISA, Neutralization, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0015
L2, the minor capsid protein of papillomavirus. PMID: 23689062
Human Papillomavirus Minor Capsid Protein L2 Mediates Intracellular Trafficking into and Passage beyond the Endoplasmic Reticulum. PMID: 35608352
Genetic variability in minor capsid protein (L2 gene) of human papillomavirus type 16 among Indian women. PMID: 35552511
Insights into the role and function of L2, the minor capsid protein of papillomaviruses. PMID: 19169853
Minor Capsid Protein L2 Polytope Induces Broad Protection against Oncogenic and Mucosal Human Papillomaviruses. PMID: 29212932
Subcellular Trafficking of the Papillomavirus Genome during Initial Infection: The Remarkable Abilities of Minor Capsid Protein L2. PMID: 29207511
Human Papillomavirus L2 Capsid Protein Stabilizes γ-Secretase during Viral Infection. PMID: 35458534
Topography of the Human Papillomavirus Minor Capsid Protein L2 during Vesicular Trafficking of Infectious Entry. PMID: 26246568
Modification of human papillomavirus minor capsid protein L2 by sumoylation. PMID: 20739540
Antibody Competition Reveals Surface Location of HPV L2 Minor Capsid Protein Residues 17-36. PMID: 29125554
Human papillomavirus 16 minor capsid protein L2 helps capsomeres assemble independently of intercapsomeric disulfide bonding. PMID: 16175337
Refolding and in vitro characterization of human papillomavirus 16 minor capsid protein L2. PMID: 30375341
Efficient Inhibition of Human Papillomavirus Infection by L2 Minor Capsid-Derived Lipopeptide. PMID: 31387913
High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility. PMID: 33568731
Human papillomavirus type 16 minor capsid protein l2 N-terminal region containing a common neutralization epitope binds to the cell surface and enters the cytoplasm. PMID: 11160736
The minor capsid protein L2 contributes to two steps in the human papillomavirus type 31 life cycle. PMID: 15767396
Production and characterization of virus-like particles of grapevine fanleaf virus presenting L2 epitope of human papillomavirus minor capsid protein. PMID: 31752839
The l2 minor capsid protein of human papillomavirus type 16 interacts with a network of nuclear import receptors. PMID: 15507604
Nuclear translocation of papillomavirus minor capsid protein L2 requires Hsc70. PMID: 15140951
Recombinant Viral Capsid Protein L2 (rVL2) of HPV 16 Suppresses Cell Proliferation and Glucose Metabolism via ITGB7/C/EBPβ Signaling Pathway in Cervical Cancer Cell Lines. PMID: 31819523
Nuclear localization but not PML protein is required for incorporation of the papillomavirus minor capsid protein L2 into virus-like particles. PMID: 14722267
The papillomavirus minor capsid protein, L2, induces localization of the major capsid protein, L1, and the viral transcription/replication protein, E2, to PML oncogenic domains. PMID: 9420209
Direct binding of retromer to human papillomavirus type 16 minor capsid protein L2 mediates endosome exit during viral infection. PMID: 25693203
Conformational and linear epitopes on virus-like particles of human papillomavirus type 33 identified by monoclonal antibodies to the minor capsid protein L2. PMID: 7595373
Chimeric human papillomavirus type 16 (HPV-16) L1 particles presenting the common neutralizing epitope for the L2 minor capsid protein of HPV-6 and HPV-16. PMID: 12857908
Preclinical refinements of a broadly protective VLP-based HPV vaccine targeting the minor capsid protein, L2. PMID: 26003490
The high risk HPV16 L2 minor capsid protein has multiple transport signals that mediate its nucleocytoplasmic traffic. PMID: 22154072
A surface immunodeterminant of human papillomavirus type 16 minor capsid protein L2. PMID: 9636375
Nuclear location of minor capsid protein L2 is required for expression of a reporter plasmid packaged in HPV51 pseudovirions. PMID: 19766281
Identification of a dynein interacting domain in the papillomavirus minor capsid protein l2. PMID: 16775357
Prophylactic papillomavirus vaccines. PMID: 24559559
Master mitotic kinases regulate viral genome delivery during papillomavirus cell entry. PMID: 36683055
Natural variants in the major neutralizing epitope of human papillomavirus minor capsid protein L2. PMID: 22961598
Virus-like Particle-Based L2 Vaccines against HPVs: Where Are We Today? PMID: 31877975
Expression pattern and subcellular localization of human papillomavirus minor capsid protein L2. PMID: 19095951
Cleavage of the HPV16 Minor Capsid Protein L2 during Virion Morphogenesis Ablates the Requirement for Cellular Furin during De Novo Infection. PMID: 26569287
Capsid display of a conserved human papillomavirus L2 peptide in the adenovirus 5 hexon protein: a candidate prophylactic hpv vaccine approach. PMID: 26362430
Nuclear import strategies of high-risk HPV18 L2 minor capsid protein. PMID: 16733063
A pan-HPV vaccine based on bacteriophage PP7 VLPs displaying broadly cross-neutralizing epitopes from the HPV minor capsid protein, L2. PMID: 21858066
Arrangement of L2 within the papillomavirus capsid. PMID: 18367526
Host cell transcriptome modification upon exogenous HPV16 L2 protein expression. PMID: 29207600
The positively charged termini of L2 minor capsid protein required for bovine papillomavirus infection function separately in nuclear import and DNA binding. PMID: 15564455
Human Papillomavirus Major Capsid Protein L1 Remains Associated with the Incoming Viral Genome throughout the Entry Process. PMID: 28566382
A membrane-destabilizing peptide in capsid protein L2 is required for egress of papillomavirus genomes from endosomes. PMID: 16378978
The l2 minor capsid protein of low-risk human papillomavirus type 11 interacts with host nuclear import receptors and viral DNA. PMID: 16873281
Critical Residues Involved in the Coassembly of L1 and L2 Capsid Proteins of Human Papillomavirus 16. PMID: 36815785
Cleavage of the papillomavirus minor capsid protein, L2, at a furin consensus site is necessary for infection. PMID: 16432208
The Cytoskeletal Adaptor Obscurin-Like 1 Interacts with the Human Papillomavirus 16 (HPV16) Capsid Protein L2 and Is Required for HPV16 Endocytosis. PMID: 27654294
Protective immunity to rabbit oral and cutaneous papillomaviruses by immunization with short peptides of L2, the minor capsid protein. PMID: 12208958
Common neutralization epitope in minor capsid protein L2 of human papillomavirus types 16 and 6. PMID: 10364381
A central region in the minor capsid protein of papillomaviruses facilitates viral genome tethering and membrane penetration for mitotic nuclear entry. PMID: 28464022
Factors influencing subcellular localization of the human papillomavirus L2 minor structural protein. PMID: 16257028
Developing vaccines against minor capsid antigen L2 to prevent papillomavirus infection. PMID: 19421199
Interaction of the papillomavirus transcription/replication factor, E2, and the viral capsid protein, L2. PMID: 11040122
Progress and prospects for L2-based human papillomavirus vaccines. PMID: 26901354
Reorganization of nuclear domain 10 induced by papillomavirus capsid protein l2. PMID: 12033769
Monoclonal antibodies recognizing cross-neutralization epitopes in human papillomavirus 16 minor capsid protein L2. PMID: 23051711
Cyclophilins facilitate dissociation of the human papillomavirus type 16 capsid protein L1 from the L2/DNA complex following virus entry. PMID: 22761365
Optimized production strategy of the major capsid protein HPV 16L1 non-assembly variant in E. coli. PMID: 32681956
Assembly of the major and the minor capsid protein of human papillomavirus type 33 into virus-like particles and tubular structures in insect cells. PMID: 8178438
RG1-VLP and Other L2-Based, Broad-Spectrum HPV Vaccine Candidates. PMID: 33802456
For research use only. Not for human or drug use.
