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InVivoMAb Anti-HIV1 env/Env polyprotein (Iv0039) (VVV03101)

Host species:Human
Isotype:IgG1, kappa
Applications:ELISA, Neutralization
Accession:P03377
Overview

Catalog No.

VVV03101

Species reactivity

Human immunodeficiency virus 1 (HIV-1)

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

Envelope glycoprotein gp160, Env polyprotein, Surface protein gp120, SU, Glycoprotein 120, gp120, Transmembrane protein gp41, TM, Glycoprotein 41, gp41, env

Concentration

1.36 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P03377

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0039

Data Image
  • SDS-PAGE
    SDS PAGE for HIV1 env/Env polyprotein (Iv0039)
References

HIV-1 Entry and Membrane Fusion Inhibitors. PMID: 33922579

How HIV-1 entry mechanism and broadly neutralizing antibodies guide structure-based vaccine design. PMID: 28422787

The env gene variability is not directly related to the high cytopathogenicity of an HIV1 variant. PMID: 2371777

Peptide Triazole Inhibitors of HIV-1: Hijackers of Env Metastability. PMID: 35692162

Sequencing the Biology of Entry: The Retroviral env Gene. PMID: 28688086

HIV-1 replication. PMID: 12465460

HIV-1 pseudoviruses constructed in China regulatory laboratory. PMID: 31859609

Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains. PMID: 29212041

RRE-dependent HIV-1 Env RNA effects on Gag protein expression, assembly and release. PMID: 24971705

Reducing HIV-1 env gene CpG frequency increases the replication capacity of the HXB2 virus strain. PMID: 35041864

HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation. PMID: 21762802

Construction and Characterization of HIV-1 env-Pseudoviruses of the Recombinant Form CRF63_02A and Subtype A6. PMID: 35501651

Immunogenicity of HIV-1 envelope glycoprotein oligomers. PMID: 20048701

Altered Env conformational dynamics as a mechanism of resistance to peptide-triazole HIV-1 inactivators. PMID: 34627310

HIV1 cytopathogenicity-genetic difference between direct cytotoxic and fusogenic effect. PMID: 1733106

Vpr Enhances HIV-1 Env Processing and Virion Infectivity in Macrophages by Modulating TET2-Dependent IFITM3 Expression. PMID: 31431548

Structure of the transmembrane domain of HIV-1 envelope glycoprotein. PMID: 27868386

Association of envelope-specific B-cell differentiation and viral selective pressure signatures in HIV-1 CRF01_AE infection. PMID: 35848590

HIV-1 Envelope FRETted Over by Antibodies. PMID: 31194935

Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer. PMID: 27992602

[Revisiting HIV-1 assembly]. PMID: 18198110

AIDS virus envelope spike structure. PMID: 17395457

Breadth of HIV-1 Env-specific antibody-dependent cellular cytotoxicity: relevance to global HIV vaccine design. PMID: 24937308

Small Molecule HIV-1 Attachment Inhibitors: Discovery, Mode of Action and Structural Basis of Inhibition. PMID: 34066522

Phylogenetics of HIV-1 subtype G env: Greater complexity and older origins than previously reported. PMID: 26190450

Dolutegravir inhibits HIV-1 Env evolution in primary human cells. PMID: 25849829

Recent advance in the structural analysis of HIV-1 envelope protein. PMID: 25921945

Defining HIV-1 Envelope N-Glycan Microdomains through Site-Specific Heterogeneity Profiles. PMID: 30305355

Variable infectivity and conserved engagement in cell-to-cell viral transfer by HIV-1 Env from Clade B transmitted founder clones. PMID: 30415130

HIV-1 Envelope Glycoprotein at the Interface of Host Restriction and Virus Evasion. PMID: 30935048

Use of dual recombinant vaccinia virus vectors to assay viral glycoprotein-mediated fusion with transfection-resistant primary cell targets. PMID: 15114024

Genotypic characterization of CRF01_AE env genes derived from human immunodeficiency virus type 1-infected patients residing in central Thailand. PMID: 19108694

Neutralization Sensitivity of HIV-1 CRF07_BC From an Untreated Patient With a Focus on Evolution Over Time. PMID: 35372102

Functional and structural segregation of overlapping helices in HIV-1. PMID: 35511220

Reverted HIV-1 Mutants in CD4+ T-Cells Reveal Critical Residues in the Polar Region of Viral Envelope Glycoprotein. PMID: 34935422

High throughput functional analysis of HIV-1 env genes without cloning. PMID: 17416428

Genotypic tests for determining coreceptor usage of HIV-1. PMID: 21288812

Variations in Env at amino acids 328 and 330 affect HIV-1 replicative fitness and entry inhibitor sensitivity. PMID: 33862046

CpG Frequency in the 5' Third of the env Gene Determines Sensitivity of Primary HIV-1 Strains to the Zinc-Finger Antiviral Protein. PMID: 31937644

Validation of an automated system for aliquoting of HIV-1 Env-pseudotyped virus stocks. PMID: 29300769

HIV Rev Assembly on the Rev Response Element (RRE): A Structural Perspective. PMID: 26075509

Centralized HIV-1 envelope immunogens and neutralizing antibodies. PMID: 18045113

HIV1 V3 loop hypermutability is enhanced by the guanine usage bias in the part of env gene coding for it. PMID: 20109155

Glucosidase inhibitors for treatment of HIV-1 infection. PMID: 1540404

Human immunodeficiency virus type 1-associated CD4 downmodulation. PMID: 7817874

Molecular Gymnastics: Mechanisms of HIV-1 Resistance to CCR5 Antagonists and Impact on Virus Phenotypes. PMID: 26324043

HIV-1 entry inhibitors: classes, applications and factors affecting potency. PMID: 17073614

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene. PMID: 25589637

Morphogenesis of human immunodeficiency virus type 1. PMID: 1388714

Envelope glycoprotein mobility on HIV-1 particles depends on the virus maturation state. PMID: 28916807

Molecular strategies to design an escape-proof antiviral therapy. PMID: 21513746

Characterization of human immunodeficiency virus type 1 CRF01_AE env genes derived from recently infected Thai individuals. PMID: 24513704

Appreciating HIV type 1 diversity: subtype differences in Env. PMID: 19327047

Deep Gene Sequence Cluster Analyses of Multi-Virus-Infected Mucosal Tissue Reveal Enhanced Transmission of Acute HIV-1. PMID: 33177204

Analysis of HIV-1 envelope cytoplasmic tail effects on viral replication. PMID: 36603533

The Changes of Positive Selection Within env Gene of HIV-1 B', CRF07_BC and CRF08_BC from China Over Time. PMID: 27917706

The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens. PMID: 9632381

Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET. PMID: 30971821

Induction of a Tier-1-Like Phenotype in Diverse Tier-2 Isolates by Agents That Guide HIV-1 Env to Perturbation-Sensitive, Nonnative States. PMID: 28490588

Different HIV-1 env frames: gp120 and ASP (antisense protein) biosynthesis, and theirs co-variation tropic amino acid signatures in X4- and R5-viruses. PMID: 27328810

Virion attachment and entry: HIV gp120 Env biotinylation, gp120 Env, or integrin ligand-binding assay. PMID: 24158809

Common principles and intermediates of viral protein-mediated fusion: the HIV-1 paradigm. PMID: 19077194

HIV-1 coreceptor preference is distinct from target cell tropism: a dual-parameter nomenclature to define viral phenotypes. PMID: 16923919

Frequency and Env determinants of HIV-1 subtype C strains from antiretroviral therapy-naive subjects that display incomplete inhibition by maraviroc. PMID: 27809912

Retromer regulates HIV-1 envelope glycoprotein trafficking and incorporation into virions. PMID: 25393110

Microsecond Dynamics and Network Analysis of the HIV-1 SOSIP Env Trimer Reveal Collective Behavior and Conserved Microdomains of the Glycan Shield. PMID: 28890362

HIV-1 mediated immune pathogenesis: spotlight on the role of viral protein R (Vpr). PMID: 19275586

Flow virometry analysis of envelope glycoprotein conformations on individual HIV virions. PMID: 28424455

Validation of HIV-1 MA Shell Structural Arrangements and Env Protein Interactions Predict a Role of the MA Shell in Viral Maturation. PMID: 37112873

Identification of HIV-1 genitourinary tract compartmentalization by analyzing the env gene sequences in urine. PMID: 26372275

The Vpr protein from HIV-1: distinct roles along the viral life cycle. PMID: 15725353

Mechanisms of infectivity and replication of HIV-1 and implications for therapy. PMID: 2178499

env Gene typing of human immunodeficiency virus type 1 strains on electronic microarrays. PMID: 15815017

Defective HIV-1 envelope gene promotes the evolution of the infectious strain through recombination in vitro. PMID: 32753067

Stabilization of a soluble, native-like trimeric form of an efficiently cleaved Indian HIV-1 clade C envelope glycoprotein. PMID: 28283570

HIV-1 subtype O: epidemiology, pathogenesis, diagnosis, and perspectives of the evolution of HIV. PMID: 8800800

Genetic and Phenotypic Analysis of CRF01_AE HIV-1 env Clones from Patients Residing in Beijing, China. PMID: 27066910

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

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For research use only. Not for human or drug use.

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InVivoMAb Anti-HIV1 env/Env polyprotein (Iv0039) [VVV03101]
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