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Recombinant Langya virus/LayV G/Glycoprotein, C-His (EVV18301)

Applications:ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system:Mammalian Cells
Accession:UUV47206.1
Protein length:Asn64-Ser624
Overview

Catalog No.

EVV18301

Expression system

Mammalian Cells

Species

Langya virus

Protein length

Asn64-Ser624

Predicted molecular weight

65.21 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

UUV47206.1

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

G protein, Glycoprotein G, G

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Langya virus/LayV G/Glycoprotein
References

Langya henipavirus: Is it a potential cause for public health concern? PMID: 36599832

Henipaviruses: an expanding global public health concern? PMID: 36219280

Langya virus outbreak in China, 2022: Are we on the verge of a new pandemic? PMID: 36212515

Is the New Langya virus in China a threat to global health? A short communication. PMID: 37113840

Vaccines against pseudorabies virus (PrV). PMID: 27890448

Full-length G glycoprotein directly extracted from rabies virus with detergent and then stabilized by amphipols in liquid and freeze-dried forms. PMID: 34297405

Ephedrae Herba and Cinnamomi Cortex interactions with G glycoprotein inhibit respiratory syncytial virus infectivity. PMID: 35079103

The use of monoclonal antibodies and lectins to identify changes in viral glycoproteins that are influenced by glycosylation: the case of human respiratory syncytial virus attachment (G) glycoprotein. PMID: 17502674

G glycoprotein amino acid residues required for human monoclonal antibody RAB1 neutralization are conserved in rabies virus street isolates. PMID: 21693135

Structure and function of respiratory syncytial virus surface glycoproteins. PMID: 24362685

VSV-G Viral Envelope Glycoprotein Prepared from Pichia pastoris Enhances Transfection of DNA into Animal Cells. PMID: 28297751

In silico identification of potential drug-like molecules against G glycoprotein of Nipah virus by molecular docking, DFT studies, and molecular dynamic simulation. PMID: 36036362

The G glycoprotein of human respiratory syncytial viruses of subgroups A and B: extensive sequence divergence between antigenically related proteins. PMID: 2441388

Unravelling Immunoglobulin G Fc N-Glycosylation: A Dynamic Marker Potentiating Predictive, Preventive and Personalised Medicine. PMID: 29382131

Human metapneumovirus glycoprotein G disrupts mitochondrial signaling in airway epithelial cells. PMID: 23626834

VHSV G glycoprotein major determinants implicated in triggering the host type I IFN antiviral response as DNA vaccine molecular adjuvants. PMID: 25203447

Immunogenicity of Different Forms of Middle East Respiratory Syndrome S Glycoprotein. PMID: 31024747

Human metapneumovirus glycoprotein G inhibits TLR4-dependent signaling in monocyte-derived dendritic cells. PMID: 21632720

The G glycoprotein of respiratory syncytial virus depresses respiratory rates through the CX3C motif and substance P. PMID: 12743318

Cysteines in the stalk of the nipah virus G glycoprotein are located in a distinct subdomain critical for fusion activation. PMID: 22496210

Monoclonal Antibody against G Glycoprotein Increases Respiratory Syncytial Virus Clearance In Vivo and Prevents Vaccine-Enhanced Diseases. PMID: 28076422

Identification of Hendra virus G glycoprotein residues that are critical for receptor binding. PMID: 17376907

Mechanism of Viral Glycoprotein Targeting by Membrane-associated-RING-CH Proteins. PMID: 33532773

Respiratory syncytial virus G glycoprotein expressed using the Semliki Forest virus replicon is biologically active. PMID: 10076512

Crystallization and preliminary X-ray analysis of Chandipura virus glycoprotein G. PMID: 22949203

Contribution of the attachment G glycoprotein to pathogenicity and immunogenicity of avian metapneumovirus subgroup C. PMID: 20408400

Vesicular Stomatitis Virus (VSV) G Glycoprotein Can Be Modified to Create a Her2/Neu-Targeted VSV That Eliminates Large Implanted Mammary Tumors. PMID: 37199666

Construction of a replication-competent retroviral vector for expression of the VSV-G envelope glycoprotein for cancer gene therapy. PMID: 32146506

Conformational Flexibility in Respiratory Syncytial Virus G Neutralizing Epitopes. PMID: 31852779

Sublingual Immunization With an RSV G Glycoprotein Fragment Primes IL-17-Mediated Immunopathology Upon Respiratory Syncytial Virus Infection. PMID: 30984173

Development of Luciferase Immunoprecipitation Systems (LIPS) Assay to Detect IgG Antibodies against Human Respiratory Syncytial Virus G-Glycoprotein. PMID: 30717190

Respiratory syncytial virus glycoprotein G interacts with DC-SIGN and L-SIGN to activate ERK1 and ERK2. PMID: 22090124

Genetic variability of the G glycoprotein gene of human metapneumovirus. PMID: 15297494

Expression of the G glycoprotein gene of human respiratory syncytial virus in Salmonella typhimurium. PMID: 8445368

Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins. PMID: 33727347

Structure-Based Design and Antigenic Validation of Respiratory Syncytial Virus G Immunogens. PMID: 35266806

Priming with secreted glycoprotein G of respiratory syncytial virus (RSV) augments interleukin-5 production and tissue eosinophilia after RSV challenge. PMID: 9525607

New insights into the Hendra virus attachment and entry process from structures of the virus G glycoprotein and its complex with Ephrin-B2. PMID: 23144952

Demonstration that glycoprotein G is the attachment protein of respiratory syncytial virus. PMID: 3655746

Transient expression of rabies virus G-glycoprotein using BHK-21 cells cultured in suspension. PMID: 25700821

Identification of the cell binding domain in Nipah virus G glycoprotein using a phage display system. PMID: 28082163

Mutational analysis of the vesicular stomatitis virus glycoprotein G for membrane fusion domains. PMID: 8389917

Vesicular Stomatitis Virus G Glycoprotein and ATRA Enhanced Bystander Killing of Chemoresistant Leukemic Cells by Herpes Simplex Virus Thymidine Kinase/Ganciclovir. PMID: 24753816

Disease severity of respiratory syncytial virus (RSV) infection correlate to a novel set of five amino acid substitutions in the RSV attachment glycoprotein (G) in China. PMID: 32194139

Production of vesicular stomatitis virus G glycoprotein (VSV-G) pseudotyped retroviral vectors. PMID: 18428407

Nucleotide sequence analysis of the ovine respiratory syncytial virus G glycoprotein gene. PMID: 8372453

The class II membrane glycoprotein G of bovine respiratory syncytial virus, expressed from a synthetic open reading frame, is incorporated into virions of recombinant bovine herpesvirus 1. PMID: 9557663

Respiratory Syncytial Virus (RSV) G Protein Vaccines With Central Conserved Domain Mutations Induce CX3C-CX3CR1 Blocking Antibodies. PMID: 33672319

Recombinant bovine adenovirus-3 co-expressing bovine respiratory syncytial virus glycoprotein G and truncated glycoprotein gD of bovine herpesvirus-1 induce immune responses in cotton rats. PMID: 25173687

Engineering a serum-resistant and thermostable vesicular stomatitis virus G glycoprotein for pseudotyping retroviral and lentiviral vectors. PMID: 23364315

Host cell effect upon glycosylation and antigenicity of human respiratory syncytial virus G glycoprotein. PMID: 8661440

Premature stop codons in the G glycoprotein of human respiratory syncytial viruses resistant to neutralization by monoclonal antibodies. PMID: 2033675

A recombinant Hendra virus G glycoprotein subunit vaccine protects nonhuman primates against Hendra virus challenge. PMID: 24522928

Amino acid variations of the immuno-dominant domain of respiratory syncytial virus attachment glycoprotein (G) affect the antibody responses In BALB/c mice. PMID: 36958697

A Hendra virus G glycoprotein subunit vaccine protects African green monkeys from Nipah virus challenge. PMID: 22875827

Henipavirus mediated membrane fusion, virus entry and targeted therapeutics. PMID: 22470837

Secreted respiratory syncytial virus G glycoprotein induces interleukin-5 (IL-5), IL-13, and eosinophilia by an IL-4-independent mechanism. PMID: 10482601

Sequence polymorphism of the predicted human metapneumovirus G glycoprotein. PMID: 14993653

Contribution of the respiratory syncytial virus G glycoprotein and its secreted and membrane-bound forms to virus replication in vitro and in vivo. PMID: 11689051

Interaction between the respiratory syncytial virus G glycoprotein cytoplasmic domain and the matrix protein. PMID: 15958665

A functional henipavirus envelope glycoprotein pseudotyped lentivirus assay system. PMID: 21073718

Contribution of respiratory syncytial virus G antigenicity to vaccine-enhanced illness and the implications for severe disease during primary respiratory syncytial virus infection. PMID: 14730270

Respiratory syncytial virus (RSV) G glycoprotein is not necessary for vaccine-enhanced disease induced by immunization with formalin-inactivated RSV. PMID: 15141000

Evaluation of the respiratory syncytial virus G-directed neutralizing antibody response in the human airway epithelial cell model. PMID: 32866728

Complete sequence of the G glycoprotein gene of avian metapneumovirus subgroup C and identification of a divergent domain in the predicted protein. PMID: 15557240

The attachment (G) glycoprotein of respiratory syncytial virus contains a single immunodominant epitope that elicits both Th1 and Th2 CD4+ T cell responses. PMID: 11086089

Pseudotransduction of hepatocytes by using concentrated pseudotyped vesicular stomatitis virus G glycoprotein (VSV-G)-Moloney murine leukemia virus-derived retrovirus vectors: comparison of VSV-G and amphotropic vectors for hepatic gene transfer. PMID: 8642678

Human metapneumovirus G protein is highly conserved within but not between genetic lineages. PMID: 23385328

Generation and epitope mapping of a sub-group cross-reactive anti-respiratory syncytial virus G glycoprotein monoclonal antibody which is protective in vivo. PMID: 24415460

CX3C chemokine mimicry by respiratory syncytial virus G glycoprotein. PMID: 11477410

O glycosylation of glycoprotein G of human respiratory syncytial virus is specified within the divergent ectodomain. PMID: 2164608

[Sequence analysis of G glycoprotein gene of human respiratory syncytial virus]. PMID: 24749351

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells. PMID: 8396259

Prophylactic treatment with a G glycoprotein monoclonal antibody reduces pulmonary inflammation in respiratory syncytial virus (RSV)-challenged naive and formalin-inactivated RSV-immunized BALB/c mice. PMID: 20592094

Conservation of G-Protein Epitopes in Respiratory Syncytial Virus (Group A) Despite Broad Genetic Diversity: Is Antibody Selection Involved in Virus Evolution? PMID: 25995258

Treatment with respiratory syncytial virus G glycoprotein monoclonal antibody or F(ab')2 components mediates reduced pulmonary inflammation in mice. PMID: 19264600

Genetic heterogeneity of the attachment glycoprotein G among group A respiratory syncytial viruses. PMID: 7985408

Backbone (1)H, (13)C, and (15)N resonance assignments of the Fc fragment of human immunoglobulin G glycoprotein. PMID: 25291979

Crystal structure of the Hendra virus attachment G glycoprotein bound to a potent cross-reactive neutralizing human monoclonal antibody. PMID: 24130486

Enhanced gene transfer with fusogenic liposomes containing vesicular stomatitis virus G glycoprotein. PMID: 9621082

Loss of conserved cysteine residues in the attachment (G) glycoprotein of two human respiratory syncytial virus escape mutants that contain multiple A-G substitutions (hypermutations). PMID: 7507282

Morphological analysis of the transfer of VSV ts-045 G glycoprotein from the endoplasmic reticulum to the intermediate compartment in vero cells. PMID: 8831570

Amino acid changes in the attachment G glycoprotein of human respiratory syncytial viruses (subgroup A) isolated in Italy over several epidemics (1997-2006). PMID: 17935190

Structures of respiratory syncytial virus G antigen bound to broadly neutralizing antibodies. PMID: 29523582

Clinical and biological consequences of respiratory syncytial virus genetic diversity. PMID: 36225856

Datasheet
$ 480
Product specifications
100 μg 480 1 mg 2880

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For research use only. Not for human or drug use.

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Recombinant Langya virus/LayV G/Glycoprotein, C-His [EVV18301]
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