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Recombinant Langya virus/LayV F/Fusion Protein, C-His (EVV18201)

Applications:ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system:Mammalian Cells
Accession:UUV47205.1
Protein length:Ser22-Ser488
Overview

Catalog No.

EVV18201

Expression system

Mammalian Cells

Species

Langya virus

Protein length

Ser22-Ser488

Predicted molecular weight

57.25 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

UUV47205.1

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

F, Fusion glycoprotein F, Fusion protein

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Langya virus/LayV F/Fusion Protein
References

Langya henipavirus: Is it a potential cause for public health concern? PMID: 36599832

Henipaviruses: an expanding global public health concern? PMID: 36219280

Langya virus outbreak in China, 2022: Are we on the verge of a new pandemic? PMID: 36212515

Is the New Langya virus in China a threat to global health? A short communication. PMID: 37113840

Transmembrane Domain Dissociation Is Required for Hendra Virus F Protein Fusogenic Activity. PMID: 31462574

A cellular Drosophila melanogaster protein with similarity to baculovirus F envelope fusion proteins. PMID: 15956544

High-yield membrane protein expression from E. coli using an engineered outer membrane protein F fusion. PMID: 23345122

Mutations in the parainfluenza virus 5 fusion protein reveal domains important for fusion triggering and metastability. PMID: 24089572

Identification of residues in the human respiratory syncytial virus fusion protein that modulate fusion activity and pathogenesis. PMID: 25339762

Triggering of the newcastle disease virus fusion protein by a chimeric attachment protein that binds to Nipah virus receptors. PMID: 21460213

Respiratory Syncytial Virus Attachment Glycoprotein Contribution to Infection Depends on the Specific Fusion Protein. PMID: 26468535

Live-cell visualization of transmembrane protein oligomerization and membrane fusion using two-fragment haptoEGFP methodology. PMID: 22385277

Development of liposomes and pseudovirions with fusion activity for efficient gene delivery. PMID: 22023472

Proteolytic activation of respiratory syncytial virus fusion protein. Cleavage at two furin consensus sequences. PMID: 11418598

Construction of Recombinant Rabies Virus Vectors Expressing H or F Protein of Peste des Petits Ruminants Virus. PMID: 36288168

Molecular Features of the Measles Virus Viral Fusion Complex That Favor Infection and Spread in the Brain. PMID: 34061592

Infectivity of a human respiratory syncytial virus lacking the SH, G, and F proteins is efficiently mediated by the vesicular stomatitis virus G protein. PMID: 12610153

Genetic diversity and evolution of human metapneumovirus fusion protein over twenty years. PMID: 19740442

Ephrin-B2 and ephrin-B3 as functional henipavirus receptors. PMID: 22227101

Studies on the fusion peptide of a paramyxovirus fusion glycoprotein: roles of conserved residues in cell fusion. PMID: 1548771

Surfactant protein A binds to the fusion glycoprotein of respiratory syncytial virus and neutralizes virion infectivity. PMID: 10558959

Low-pH triggering of human metapneumovirus fusion: essential residues and importance in entry. PMID: 19036821

Cytogenetic mapping of the Muller F element genes in Drosophila willistoni group. PMID: 25134938

Sendai-viral HN and F glycoproteins as probes of plasma-membrane protein catabolism in HTC cells. Studies with fusogenic reconstituted Sendai-viral envelopes. PMID: 3036074

Blue native PAGE and biomolecular complementation reveal a tetrameric or higher-order oligomer organization of the physiological measles virus attachment protein H. PMID: 20861270

Meeting report VLPNPV: Session 3: Immune responses. PMID: 25529229

The presence and cleavage of interpeptide disulfide bonds in viral glycoproteins. PMID: 230184

Virus-like particle vaccine primes immune responses preventing inactivated-virus vaccine-enhanced disease against respiratory syncytial virus. PMID: 28846899

Novel pneumoviruses (PnVs): Evolution and inflammatory pathology. PMID: 23763766

Cleavage at the furin consensus sequence RAR/KR(109) and presence of the intervening peptide of the respiratory syncytial virus fusion protein are dispensable for virus replication in cell culture. PMID: 12186905

Genetic diversity and molecular evolution of the major human metapneumovirus surface glycoproteins over a decade. PMID: 24041471

Respiratory syncytial virus F and G proteins induce interleukin 1alpha, CC, and CXC chemokine responses by normal human bronchoepithelial cells. PMID: 20205592

Mucosal Delivery of Recombinant Vesicular Stomatitis Virus Vectors Expressing Envelope Proteins of Respiratory Syncytial Virus Induces Protective Immunity in Cotton Rats. PMID: 33408176

Nonglycosylated G-Protein Vaccine Protects against Homologous and Heterologous Respiratory Syncytial Virus (RSV) Challenge, while Glycosylated G Enhances RSV Lung Pathology and Cytokine Levels. PMID: 26018164

Cystic fibrosis transmembrane conductance regulator activation stimulates endosome fusion in vivo. PMID: 8901608

Antibody prophylaxis and therapy against Nipah virus infection in hamsters. PMID: 16439553

Development of nested PCR assays for detection of bovine respiratory syncytial virus in clinical samples. PMID: 7814551

Different patterns of cytokine induction in cultures of respiratory syncytial (RS) virus-specific human TH cell lines following stimulation with RS virus and RS virus proteins. PMID: 8818960

New insights into the Hendra virus attachment and entry process from structures of the virus G glycoprotein and its complex with Ephrin-B2. PMID: 23144952

Klebsiella aerogenes UreF: identification of the UreG binding site and role in enhancing the fidelity of urease activation. PMID: 22369361

Inhibition of airway Na+ transport by respiratory syncytial virus. PMID: 17287265

Identification of subgroups of bovine respiratory syncytial virus. PMID: 1583108

Replication-competent or attenuated, nonpropagating vesicular stomatitis viruses expressing respiratory syncytial virus (RSV) antigens protect mice against RSV challenge. PMID: 11602747

Membrane-bound antiviral antibodies as receptors for Sendai virions in receptor-depleted erythrocytes. PMID: 6093364

Restriction fragment length polymorphism analysis of the F gene of Newcastle disease viruses isolated from chickens and an owl in Taiwan. PMID: 10593575

Photosystem I gene cassettes are present in marine virus genomes. PMID: 19710652

Molecular characterization, isolation, pathology and pathotyping of peafowl (Pavo cristatus) origin Newcastle disease virus isolates recovered from disease outbreaks in three states of India. PMID: 27724072

Immunogenetic responses in calves to intranasal delivery of bovine respiratory syncytial virus (BRSV) epitopes encapsulated in poly (DL-lactide-co-glycolide) microparticles. PMID: 23890818

Viral proteins in cell fusion. PMID: 6310822

Neuronal and non-neuronal collapsin-1 binding sites in developing chick are distinct from other semaphorin binding sites. PMID: 9364065

Alpha and lambda interferon together mediate suppression of CD4 T cells induced by respiratory syncytial virus. PMID: 16641294

Local and systemic immune responses in mice to intranasal delivery of peptides representing bovine respiratory syncytial virus epitopes encapsulated in poly (DL-lactide-co-glycolide) microparticles. PMID: 23312498

Virus-induced fusion of human erythrocyte ghosts. I. Effects of macromolecules on the final stages of the fusion reaction. PMID: 6268155

Analysis of myogenesis by somatic cell hybridization: III. Myogenic competence of hybrids derived from rat L6 myoblasts and mouse primary fibroblasts and myoblasts. PMID: 6836450

Virus-specific CD8+ T lymphocytes downregulate T helper cell type 2 cytokine secretion and pulmonary eosinophilia during experimental murine respiratory syncytial virus infection. PMID: 9236194

Virus-specific memory and effector T lymphocytes exhibit different cytokine responses to antigens during experimental murine respiratory syncytial virus infection. PMID: 8985399

Efficient reverse genetics reveals genetic determinants of budding and fusogenic differences between Nipah and Hendra viruses and enables real-time monitoring of viral spread in small animal models of henipavirus infection. PMID: 25392218

Protection of cotton rats against human respiratory syncytial virus by vaccination with a novel chimeric FG glycoprotein. PMID: 2677234

Diagnosis of enzootic pneumonia in Danish cattle: reverse transcription-polymerase chain reaction assay for detection of bovine respiratory syncytial virus in naturally and experimentally infected cattle. PMID: 12968754

Role of envelope proteins of paramyxoviruses in the modification of cell membrane antigens. PMID: 229798

Hemagglutinating and fusogenic activities of Newcastle disease virus: studies on receptor binding specificity and pH-induced conformational changes. PMID: 8551956

[Development of PCR tests for the detection of bovine herpesvirus-1, bovine respiratory syncytial viruses and pestiviruses]. PMID: 7817501

Mapping genomic loci implicates genes and synaptic biology in schizophrenia. PMID: 27435468

Cellular GFP Toxicity and Immunogenicity: Potential Confounders in in Vivo Cell Tracking Experiments. PMID: 31776511

MLLT3 governs human haematopoietic stem-cell self-renewal and engraftment. PMID: 29950403

Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis. PMID: 30742090

Phosphoinositides: multipurpose cellular lipids with emerging roles in cell death. PMID: 27557668

Convergent evolution of defensin sequence, structure and function. PMID: 35667884

Potential Role of Silencing Ribonucleic Acid for Esophageal Cancer Treatment. PMID: 20846732

Targeting DNA methylation for epigenetic therapy. PMID: 30527662

Promoter-Enhancer Communication Occurs Primarily within Insulated Neighborhoods. PMID: 35015081

Defensin-lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics. PMID: 29224149

Nucleosome Occupancy and Methylome Sequencing (NOMe-seq). PMID: 28770291

Tumor cell membrane-targeting cationic antimicrobial peptides: novel insights into mechanisms of action and therapeutic prospects. PMID: 36069787

Epigenetic remodeling by vitamin C potentiates plasma cell differentiation. PMID: 28270516

Cbx3 maintains lineage specificity during neural differentiation. PMID: 33870645

HOTAIR-Loaded Mesenchymal Stem/Stromal Cell Extracellular Vesicles Enhance Angiogenesis and Wound Healing. PMID: 31722200

Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly. PMID: 35204765

Human β-Defensin 2 (HBD-2) Displays Oncolytic Activity but Does Not Affect Tumour Cell Migration. PMID: 27847259

Ribosome biogenesis is dynamically regulated during osteoblast differentiation. PMID: 29773800

X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex. PMID: 36583030

Association of Programmed Death-Ligand 1 Expression with Aggressive Histological Types of Thyroid Carcinoma. PMID: 31031739

Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32. PMID: 30050988

Human β-defensin 2 kills Candida albicans through phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization. PMID: 36859344

Crocodile defensin (CpoBD13) antifungal activity via pH-dependent phospholipid targeting and membrane disruption. PMID: 29078982

Topical Reformulation of Valsartan for Treatment of Chronic Diabetic Wounds. PMID: 30892196

Ex Vivo Evaluation of Mouse Brain Elasticity Using High-Frequency Ultrasound Elastography. PMID: 22870770

[The nurse/nurses' aide combination and septic shock]. PMID: 31515496

A high-resolution 3D epigenomic map reveals insights into the creation of the prostate cancer transcriptome. PMID: 20561089

Adaptive evolution in subterranean termite antifungal peptides. PMID: 27297472

The Defensins Consist of Two Independent, Convergent Protein Superfamilies. PMID: 24692446

Phosphoinositide-mediated oligomerization of a defensin induces cell lysis. PMID: 13661229

Next stop; outer space. PMID: 28176797

Nucleosome Positioning and NDR Structure at RNA Polymerase III Promoters. PMID: 18306263

Synthesis and biological evaluation of cruentaren A analogues. PMID: 33024315

Preconditioning of surgical pedicle flaps with DNA plasmid expressing hypoxia-inducible factor-1α (HIF-1α) promotes tissue viability. PMID: 29619144

Efficacy of Chitosan-Based Dressing for Control of Bleeding in Excisional Wounds. PMID: 21708164

Subterranean termite prophylactic secretions and external antifungal defenses. PMID: 29359392

Importance of phosphoinositide binding by human β-defensin 3 for Akt-dependent cytokine induction. PMID: 29117547

A Prostate Cancer Risk Element Functions as a Repressive Loop that Regulates HOXA13. PMID: 30794440

Structural and functional characterization of the membrane-permeabilizing activity of Nicotiana occidentalis defensin NoD173 and protein engineering to enhance oncolysis. PMID: 33515001

Corrigendum to: Tie2-dependent knockout of HIF-1 impairs burn wound vascularization and homing of bone marrow-derived angiogenic cells. PMID: 25747664

The role of DNA methylation in directing the functional organization of the cancer epigenome. PMID: 26727887

Knockout of Angiotensin AT2 receptors accelerates healing but impairs quality. PMID: 31290765

Targeting the Hedgehog Pathway Using Itraconazole to Prevent Progression of Barrett's Esophagus to Invasive Esophageal Adenocarcinoma. PMID: 22511788

Dimerization of plant defensin NaD1 enhances its antifungal activity. PMID: 30555922

Using 3D epigenomic maps of primary olfactory neuronal cells from living individuals to understand gene regulation. PMID: 25263941

Gene body methylation can alter gene expression and is a therapeutic target in cancer. PMID: 27153539

Bivalent Regions of Cytosine Methylation and H3K27 Acetylation Suggest an Active Role for DNA Methylation at Enhancers. PMID: 24515120

Reprogramming of the human intestinal epigenome by surgical tissue transposition. PMID: 18339623

The plant defensin, NaD1, enters the cytoplasm of Fusarium oxysporum hyphae. PMID: 26657293

Human β-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation. PMID: 22960375

Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules. PMID: 22442231

Recombinant expression and purification of the tomato defensin TPP3 and its preliminary X-ray crystallographic analysis. PMID: 28741756

Structure of the defensin NsD7 in complex with PIP2 reveals that defensin : lipid oligomer topologies are dependent on lipid type. PMID: 28595297

FGFR2 mutations in bent bone dysplasia syndrome activate nucleolar stress and perturb cell fate determination. PMID: 21226170

Disulfonimide-catalyzed asymmetric vinylogous and bisvinylogous Mukaiyama aldol reactions. PMID: 24495600

The C-terminal propeptide of a plant defensin confers cytoprotective and subcellular targeting functions. PMID: 20388667

A pollen-specific RALF from tomato that regulates pollen tube elongation. PMID: 15638771

Defensins--components of the innate immune system in plants. PMID: 27647905

Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization. PMID: 19437518

A powerful chiral counteranion motif for asymmetric catalysis. PMID: 30455721

A comprehensive characterization of aggravated aging-related changes in T lymphocytes and monocytes in end-stage renal disease: the iESRD study. PMID: 27324319

A non-invasive method to produce pressure ulcers of varying severity in a spinal cord-injured rat model. PMID: 24434934

Strengthening the skin with topical delivery of keratinocyte growth factor-1 using a novel DNA plasmid. PMID: 18498107

Novel insights on the mechanism of action of alpha-amylase inhibitors from the plant defensin family. PMID: 22028336

Tie2-dependent knockout of HIF-1 impairs burn wound vascularization and homing of bone marrow-derived angiogenic cells. PMID: 12846570

Structure of Petunia hybrida defensin 1, a novel plant defensin with five disulfide bonds. PMID: 27956674

Patient reported outcome of adult perioperative anaesthesia in the United Kingdom: a cross-sectional observational study. PMID: 12644678

Isolation and properties of floral defensins from ornamental tobacco and petunia. PMID: 29988679

Anti-cytomegalovirus IgG antibody titer is positively associated with advanced T cell differentiation and coronary artery disease in end-stage renal disease. PMID: 19367256

Short-term correction of arginase deficiency in a neonatal murine model with a helper-dependent adenoviral vector. PMID: 25802281

The Tomato Defensin TPP3 Binds Phosphatidylinositol (4,5)-Bisphosphate via a Conserved Dimeric Cationic Grip Conformation To Mediate Cell Lysis. PMID: 11743274

Perioperative complications of laparoscopic radical prostatectomy: the Montsouris 3-year experience. PMID: 15593084

De novo renal cell carcinoma of native kidney in renal transplant recipients. PMID: 11311786

Datasheet
$ 480
Product specifications
100 μg 480 1 mg 2880

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Recombinant Langya virus/LayV F/Fusion Protein, C-His [EVV18201]
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