Catalog No.
YHA19001
Description
Recombinant Human UBE2C Protein, N-His (YHA19001) is expressed in E. coli and spans Ala2-Pro179. His-tagged for convenient purification and detection, this protein is suitable for ELISA, immunogen, WB and ongoing bioactivity testing. Purity: >90% by SDS-PAGE.
Product Features
- Human UBE2C — Covers amino acid residues Ala2-Pro179 with a predicted molecular weight of 21.83 kDa
- N-His Tag Labeling — Facilitates efficient protein purification, routine detection and experimental operation
- High Purity Quality — Protein purity verified over 90% via SDS-PAGE detection
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Pro179
Predicted molecular weight
21.83 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
E2 ubiquitin-conjugating enzyme C, UBE2C, Ubiquitin carrier protein C, UbcH10, (E3-independent) E2 ubiquitin-conjugating enzyme C, Ubiquitin-conjugating enzyme E2 C, Ubiquitin-protein ligase C, UBCH10
Background
Recombinant Human UBE2C Protein, N-His (YHA19001) is expressed in E. coli and spans Ala2-Pro179. UBE2C is a core E2 ubiquitin-conjugating enzyme responsible for APC/C-mediated mitotic regulation. It catalyzes K11-linked polyubiquitination and subsequent degradation of cell cycle-related substrates, precisely controlling mitosis progression and genomic integrity. Dysregulation of UBE2C is tightly linked to tumor development, making it a key target for cancer biological research and drug discovery. This high-quality recombinant protein exhibits stable activity and excellent batch reproducibility for ubiquitination mechanism studies and preclinical drug research.
Note
For research use only.
For research use only. Not for human or drug use.
