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Recombinant Human papillomavirus 52 E6/Protein E6 Protein, N-His

Catalog #:   YVV17501 Specific References (96) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P36814
Protein length: Met1-Val148
Overview

Catalog No.

YVV17501

Expression system

E. coli

Species

Human papillomavirus 52

Protein length

Met1-Val148

Predicted molecular weight

20.06 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P36814

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Protein E6, E6

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human papillomavirus 52 E6/Protein E6 Protein
References

Genetic variation of E6 and E7 genes of human papillomavirus 52 from Central China. PMID: 33230866

The possible impact of novel mutations in human papillomavirus 52 on the infection characteristics. PMID: 37103992

Characteristics of human papillomavirus infection among females and the genetic variations of HPV18 and HPV58 in Henan province, China. PMID: 36755053

Genetic variability in the E6 and E7 oncogenes of HPV52 and its prevalence in the Taizhou area, China. PMID: 36415002

The HPV E6/E7 Oncogenes: Key Factors for Viral Carcinogenesis and Therapeutic Targets. PMID: 28823569

Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53. PMID: 26789255

Structure and function of the papillomavirus E6 protein and its interacting proteins. PMID: 17981532

Effects of HPV16 E6 protein on Daxx-induced apoptosis in C33A cells. PMID: 32782452

[Expression of HPV16 E6 recombinant protein and preparation of its rabbit polyclonal antibody]. PMID: 32389175

Structure of High-Risk Papillomavirus 31 E6 Oncogenic Protein and Characterization of E6/E6AP/p53 Complex Formation. PMID: 33115863

The ubiquitin-protein ligase E6-associated protein (E6-AP) serves as its own substrate. PMID: 9688277

Determinants of stability for the E6 protein of papillomavirus type 16. PMID: 19244625

High-Risk Mucosal Human Papillomavirus 16 (HPV16) E6 Protein and Cutaneous HPV5 and HPV8 E6 Proteins Employ Distinct Strategies To Interfere with Interferon Regulatory Factor 3-Mediated Beta Interferon Expression. PMID: 35475668

The high-risk HPV E6 proteins modify the activity of the eIF4E protein via the MEK/ERK and AKT/PKB pathways. PMID: 32981220

Differential localization of HPV16 E6 splice products with E6-associated protein. PMID: 15960845

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. PMID: 8221889

HPV16 E6 Controls the Gap Junction Protein Cx43 in Cervical Tumour Cells. PMID: 26445057

E6^E7, a novel splice isoform protein of human papillomavirus 16, stabilizes viral E6 and E7 oncoproteins via HSP90 and GRP78. PMID: 25691589

Design of a PDZbody, a bivalent binder of the E6 protein from human papillomavirus. PMID: 25797137

Strategies for bacterial expression of protein-peptide complexes: application to solubilization of papillomavirus E6. PMID: 21777678

The HPV16 E6 binding protein Tip-1 interacts with ARHGEF16, which activates Cdc42. PMID: 21139582

Ubiquitin-dependent proteolysis of trihydrophobin 1 (TH1) by the human papilloma virus E6-associated protein (E6-AP). PMID: 17131388

Human papillomavirus type 18 E6*, E6, and E7 protein synthesis in cell-free translation systems and comparison of E6 and E7 in vitro translation products to proteins immunoprecipitated from human epithelial cells. PMID: 1651423

Identification of the HPV-16 E6 protein from transformed mouse cells and human cervical carcinoma cell lines. PMID: 3036495

E6 protein of human papillomavirus 16 (HPV16) expressed in Escherichia coli sans a stretch of hydrophobic amino acids, enables purification of GST-ΔE6 in the soluble form and retains the binding ability to p53. PMID: 24012792

Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins. PMID: 1321031

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. PMID: 8380895

Is viral E6 oncoprotein a viable target? A critical analysis in the context of cervical cancer. PMID: 32483862

Alternatively spliced HPV-18 E6* protein inhibits E6 mediated degradation of p53 and suppresses transformed cell growth. PMID: 9233760

The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300. PMID: 10487758

Human papillomavirus type 16 E6 protein interacts with cystic fibrosis transmembrane regulator-associated ligand and promotes E6-associated protein-mediated ubiquitination and proteasomal degradation. PMID: 16878151

Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97. PMID: 21113079

Escape of p53 protein from E6-mediated degradation in HeLa cells after cisplatin therapy. PMID: 12209989

Molecular insights into the interaction of HPV-16 E6 variants against MAGI-1 PDZ1 domain. PMID: 35115618

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. PMID: 7708685

Expression of human papillomavirus type 16 E6 protein by recombinant baculovirus and use for detection of anti-E6 antibodies in human sera. PMID: 1328490

The expression of human papillomavirus type 18 E6 protein in bacteria and the production of anti-E6 antibodies. PMID: 3018129

The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation. PMID: 9858596

Mechanism of HPV E6 proteins in cellular transformation. PMID: 9284524

A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. PMID: 1661671

The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase. PMID: 9407131

Interaction of papillomavirus E6 oncoproteins with a putative calcium-binding protein. PMID: 7624774

Molecular Probing of the HPV-16 E6 Protein Alpha Helix Binding Groove with Small Molecule Inhibitors. PMID: 26915086

Design and characterization of helical peptides that inhibit the E6 protein of papillomavirus. PMID: 15182185

The DNA repair protein, O(6)-methylguanine-DNA methyltransferase is a proteolytic target for the E6 human papillomavirus oncoprotein. PMID: 12185595

Stabilization of HPV16 E6 protein by PDZ proteins, and potential implications for genome maintenance. PMID: 21489588

Innovative nomogram for cervical cancer prediction: integrating high-risk HPV infection, p53 genotype, and blood routine parameters., PMID:40463873

L1 Capsid Protein Expression in HPV-Positive Barrett Metaplasia-Dysplasia-Adenocarcinoma Lesions., PMID:40358417

Evaluation of Onco E6 point of care rapid diagnostic test for human papilloma virus in Bahir Dar, Amhara Regional State, Ethiopia., PMID:40238760

Human Papillomavirus Type 16 E6 Seroprevalence among Men Living with HIV without HPV-Driven Malignancies., PMID:39907040

Comparative efficacy of HPV 16/18 DNA and E6/E7 mRNA testing in detecting high-grade cervical lesions (CIN2+) in women with cervical biopsies., PMID:39733635

Human papillomavirus E6 alters Toll-like receptor 9 transcripts and chemotherapy responses in breast cancer cells in vitro., PMID:39644451

Novel strategies in HPV‑16‑related cervical cancer treatment: An in vitro study of combined siRNA-E5 with oxaliplatin and ifosfamide chemotherapy., PMID:39218415

Phylogenetic analysis and antigenic epitope prediction for E6 and E7 of Alpha-papillomavirus 9 in Taizhou, China., PMID:38778248

Detection of serum biomarkers of HPV-16 driven oropharynx and oral cavity cancer in Brazil., PMID:38150987

Impact of HPV strains on molecular mechanisms of cervix cancer., PMID:38036109

A novel HPV16 splicing enhancer critical for viral oncogene expression and cell immortalization., PMID:37994701

Intra-Patient Genomic Variations of Human Papillomavirus Type 31 in Cervical Cancer and Precancer., PMID:37896881

Multiple infections containing the top five prevalent HPV genotypes and their impact on cervical lesions in Changzhou, China., PMID:37584193

Cervical carcinogenesis risk association of HPV33 E6 and E7 genetic variations in Taizhou, Southeast China., PMID:37468974

[Control study of HPV E6/E7 mRNA and p16 immunohistochemistry detection in oropharyngeal squamous cell carcinoma]., PMID:37408407

A cross-sectional study of human papillomavirus genotype distribution and integration status in penile cancer among Chinese population., PMID:37244055

Characteristics of human papillomavirus infection among females and the genetic variations of HPV18 and HPV58 in Henan province, China., PMID:36755053

Genetic variability in the E6 and E7 oncogenes of HPV52 and its prevalence in the Taizhou area, China., PMID:36415002

A novel multi-epitope vaccine of HPV16 E5E6E7 oncoprotein delivered by HBc VLPs induced efficient prophylactic and therapeutic antitumor immunity in tumor mice model., PMID:36376215

Serologic Response to Human Papillomavirus Genotypes Among Unvaccinated Women: Findings From the HITCH Cohort Study., PMID:36322543

Cottontail rabbit papillomavirus E6 proteins: Interaction with MAML1 and modulation of the Notch signaling pathway., PMID:36155393

High prevalence of and factors associated with human papillomavirus infection among women attending a tertiary hospital in Gauteng Province, South Africa., PMID:35931978

Expression of CD44v6 and RCAS1 in Uterine Cervical Carcinoma Infected with Human Papillomavirus and Its Effect on Cell Proliferation and Differentiation., PMID:35901351

Determination of human papillomavirus type in archival tissue specimens of invasive cervical cancer using molecular mapping and E6/E7-based polymerase chain reaction., PMID:35381047

Prevalence and distribution of human papillomavirus (HPV) in Luoyang city of Henan province during 2015-2021 and the genetic variability of HPV16 and 52., PMID:35246180

The polymorphism analysis and epitope predicted of Alphapapillomavirus 9 E6 in Sichuan, China., PMID:35057815

High-risk human papillomavirus-18 uses an mRNA sequence to synthesize oncoprotein E6 in tumors., PMID:34615711

The genetic variability, phylogeny and functional significance of E6, E7 and LCR in human papillomavirus type 52 isolates in Sichuan, China., PMID:33941222

Accuracy of HPV E6/E7 mRNA examination using in situ hybridization in diagnosing cervical intraepithelial lesions., PMID:33608003

EGFR Protein Expression Relates with Tumor Histology, Methylation Status of EGFR and HPV16 E6 Viral Load in Oropharyngeal Carcinoma., PMID:33428063

The role of HPV gene expression and selected cellular MiRNAs in lung cancer development., PMID:33301856

Genetic variation of E6 and E7 genes of human papillomavirus 52 from Central China., PMID:33230866

Analysis of factors affecting the prognosis of patients with cervical intraepithelial neoplasia 2., PMID:32724424

Role of molecular biomarker human papilloma virus (HPV) E6 oncoprotein in cervical cancer screening., PMID:32680634

Risk stratification of HPV 16 DNA methylation combined with E6 oncoprotein in cervical cancer screening: a 10-year prospective cohort study., PMID:32381054

Detection of HPV E6 oncoprotein from urine via a novel immunochromatographic assay., PMID:32320451

High prevalence of human papillomavirus and European variants of HPV 16 infecting concomitantly to cervix and oral cavity in HIV positive women., PMID:32320400

Antibodies against human papillomavirus proteins in Barrett's dysplasia and intramucosal esophageal adenocarcinoma., PMID:32170783

Differential expression of human papillomavirus 16-, 18-, 52-, and 58-derived transcripts in cervical intraepithelial neoplasia., PMID:32143682

The Use of Both Therapeutic and Prophylactic Vaccines in the Therapy of Papillomavirus Disease., PMID:32133000

A Phase II, Prospective, Randomized, Multicenter, Open-Label Study of GX-188E, an HPV DNA Vaccine, in Patients with Cervical Intraepithelial Neoplasia 3., PMID:31727676

Human papillomavirus (HPV) can establish productive infection in dysplastic oral mucosa, but HPV status is poorly predicted by histological features and p16 expression., PMID:31617604

Expression of toll-like receptors in non-endemic nasopharyngeal carcinoma., PMID:31238894

[Effects of hnRNP E1 and both early genes E2 and E6 of HPV16 together with their interactions on cervical carcinogenesis]., PMID:31006210

Whole-Genome Analysis of Human Papillomavirus Type 16 Prevalent in Japanese Women with or without Cervical Lesions., PMID:30995759

Oncogenicitiy Comparison of Human Papillomavirus Type 52 E6 Variants., PMID:30676312

Human Papillomavirus (HPV) 16/18 E6 Oncoprotein Expression in Infections with Single and Multiple Genotypes., PMID:30606718

Genetic variability of human papillomavirus type 51 E6, E7, L1 and L2 genes in Southwest China., PMID:30583025

In HPV-Positive HNSCC Cells, Functional Restoration of the p53/p21 Pathway by Proteasome Inhibitor Bortezomib Does Not Affect Radio- or Chemosensitivity., PMID:30554133

High frequency of HPV16 European variant E350G among Mexican women from Sinaloa., PMID:30425223

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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Recombinant Human papillomavirus 52 E6/Protein E6 Protein, N-His [YVV17501]
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