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Recombinant Monkeypox virus/MPXV A29L Protein, C-His

Catalog #:   EVV13401 Specific References (90) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: Mammalian Cells
Protein length: Asp2-Glu110
Overview

Catalog No.

EVV13401

Expression system

Mammalian Cells

Species

Monkeypox virus (strain Zaire-96-I-16) (MPX)

Protein length

Asp2-Glu110

Predicted molecular weight

15.33 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

A29L,A29

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Monkeypox virus/MPXV A29L Protein
  • Bioactivity
    Anti-MPXV A29L Antibody (SAA0286) binds with A29L protein
References

Monkeypox Virus in Nigeria: Infection Biology, Epidemiology, and Evolution. PMID: 33167496

Detection of monkeypox virus with real-time PCR assays. PMID: 16731033

Monkeypox virus and insights into its immunomodulatory proteins. PMID: 18837778

A review of the monkeypox virus and a recent outbreak of skin rash disease in Nigeria. PMID: 30357851

The 2022 outbreak and the pathobiology of the monkeypox virus. PMID: 35760647

Analysis of the monkeypox virus genome. PMID: 12083817

Monkeypox Virus Infection in Humans across 16 Countries - April-June 2022. PMID: 35866746

Exportation of Monkeypox Virus From the African Continent. PMID: 32880628

Vaccinating against monkeypox in the Democratic Republic of the Congo. PMID: 30445121

The monkeypox virus. PMID: 35654445

Human Monkeypox: Epidemiologic and Clinical Characteristics, Diagnosis, and Prevention. PMID: 30981594

Monkeypox. PMID: 34662033

Real-time PCR assays for the specific detection of monkeypox virus West African and Congo Basin strain DNA. PMID: 20643162

Human-to-Human Transmission of Monkeypox Virus, United Kingdom, October 2018. PMID: 32023204

Monkeypox virus emergence in wild chimpanzees reveals distinct clinical outcomes and viral diversity. PMID: 32341480

Human monkeypox: an emerging zoonosis. PMID: 14720564

Monkeypox virus: a re-emergent threat to humans. PMID: 35820590

Monkeypox virus: histologic, immunohistochemical and electron-microscopic findings. PMID: 15660652

Monkeypox virus emerges from the shadow of its more infamous cousin: family biology matters. PMID: 35751396

The changing epidemiology of human monkeypox-A potential threat? A systematic review. PMID: 35148313

The transmission potential of monkeypox virus in human populations. PMID: 2850277

Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model. PMID: 33536322

Genomic variability of monkeypox virus among humans, Democratic Republic of the Congo. PMID: 24457084

Phylogenomic characterization and signs of microevolution in the 2022 multi-country outbreak of monkeypox virus. PMID: 35750157

Outbreak of human monkeypox in Nigeria in 2017-18: a clinical and epidemiological report. PMID: 31285143

Reemergence of Human Monkeypox and Declining Population Immunity in the Context of Urbanization, Nigeria, 2017-2020. PMID: 33756100

Status of human monkeypox: clinical disease, epidemiology and research. PMID: 22185831

Monkeypox re-emergence in Africa: a call to expand the concept and practice of One Health. PMID: 30625020

Efficient assembly of a large fragment of monkeypox virus genome as a qPCR template using dual-selection based transformation-associated recombination. PMID: 35393265

Human monkeypox: an emerging zoonotic disease. PMID: 17661673

A systematic review of the epidemiology of human monkeypox outbreaks and implications for outbreak strategy. PMID: 31618206

Human monkeypox and smallpox viruses: genomic comparison. PMID: 11734207

Virulence differences between monkeypox virus isolates from West Africa and the Congo basin. PMID: 16023693

Diagnosis of Imported Monkeypox, Israel, 2018. PMID: 30848724

Monkeypox in a Traveler Returning from Nigeria - Dallas, Texas, July 2021. PMID: 35389974

A tale of two clades: monkeypox viruses. PMID: 16186219

Monkeypox virus case with maculopapular exanthem and proctitis during the Spanish outbreak in 2022. PMID: 35675097

Human monkeypox - After 40聽years, an unintended consequence of smallpox eradication. PMID: 32417140

Imported Monkeypox, Singapore. PMID: 32338590

Reemergence of monkeypox: prevalence, diagnostics, and countermeasures. PMID: 16288402

Human monkeypox, 1970-79. PMID: 6249508

Ongoing monkeypox virus outbreak, Portugal, 29 April to 23 May 2022. PMID: 35656830

Clinical Course and Outcome of Human Monkeypox in Nigeria. PMID: 32052029

Transmission of monkeypox virus through sexual contact - A novel route of infection. PMID: 35659548

The detection of monkeypox in humans in the Western Hemisphere. PMID: 14736926

Evaluation of the GeneXpert for Human Monkeypox Diagnosis. PMID: 27994107

Monkeypox: A New Threat? PMID: 35887214

Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022. PMID: 35656836

The Evolving Epidemiology of Human Monkeypox: Questions Still to Be Answered. PMID: 33871010

Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022. PMID: 35837964

Monkeypox virus phylogenetic similarities between a human case detected in Cameroon in 2018 and the 2017-2018 outbreak in Nigeria. PMID: 30634001

Three neutralizing mAbs induced by MPXV A29L protein recognizing different epitopes act synergistically against orthopoxvirus. PMID: 37288876

Rational development of multicomponent mRNA vaccine candidates against mpox. PMID: 36947428

BoHV-4-Based Vector Single Heterologous Antigen Delivery Protects STAT1(-/-) Mice from Monkeypoxvirus Lethal Challenge. PMID: 26086739

Monkeypox virus quadrivalent mRNA vaccine induces immune response and protects against vaccinia virus. PMID: 37117161

A Pathogen-Mimicking Monkeypox Virus Nanovaccine Inspired by Assembly of Viral Antigens with β-Glucan and Dendrimer., PMID:40366370

A Hybrid Plasmonic Nanoplatform for One-Pot DNA and Antibody Detection of Hepatitis B, Monkeypox, and Associated Infections., PMID:40143629

Rational mpox vaccine design: immunogenicity and protective effect of individual and multicomponent proteins in mice., PMID:40105863

Immunogenicity of monkeypox virus surface proteins and cross-reactive antibody responses in vaccinated and infected individuals: implications for vaccine and therapeutic development., PMID:39994775

Chicken-Derived Single-Chain Variable Fragments Targeting Monkeypox Virus A29L Protein., PMID:39989243

Optical biosensing of monkeypox virus using novel recombinant silica-binding proteins for site-directed antibody immobilization., PMID:39850236

Chemical cross-linking facilitates antigen uptake and presentation and provides improved protection from Mpox with a dual-antigen subunit vaccine., PMID:39781294

Long-Lasting Protection and Dose Optimization of MPXV Polyvalent Mpox mRNA Vaccines Against Lethal Vaccinia Virus Challenge in Mice., PMID:39726255

A penta-component mpox mRNA vaccine induces protective immunity in nonhuman primates., PMID:39639037

Monkeypox virus A29L protein as the target for specific diagnosis and serological analysis., PMID:39570405

Programmable Macrophage Vesicle Based Bionic Self-Adjuvanting Vaccine for Immunization against Monkeypox Virus., PMID:39513669

Rational design and computational evaluation of a multi-epitope vaccine for monkeypox virus: Insights into binding stability and immunological memory., PMID:39247273

The Generation and Characterization of Monoclonal Antibodies against the MPXV A29L Protein., PMID:39205158

Monkeypox virus protein H3L induces injuries in human and mouse., PMID:39168969

A clinically used anti-human papilloma virus agent (3-hydroxyphthalic anhydride-modified bovine β-lactoglobulin) has a potential for topical application to prevent sexual transmission of monkeypox virus., PMID:39105195

Analysis of binding and authentic virus-neutralizing activities of immune sera induced by various monkeypox virus antigens., PMID:38829493

Longitudinal viral shedding and antibody response characteristics of men with acute infection of monkeypox virus: a prospective cohort study., PMID:38802350

Polyvalent mpox mRNA vaccines elicit robust immune responses and confer potent protection against vaccinia virus., PMID:38787725

Levels of antibodies against the monkeypox virus compared by HIV status and historical smallpox vaccinations: a serological study., PMID:38767199

Rapid identification of A29L antibodies based on mRNA immunization and high-throughput single B cell sequencing to detect Monkeypox virus., PMID:38517731

In silico development of a novel anti-mutation, multi-epitope mRNA vaccine against MPXV variants of emerging lineage and sub-lineages by using immunoinformatics approaches., PMID:38450722

Development and validation of a highly specific in-house chemiluminescent-based serological assay for the detection of antibodies directed against the human monkeypox virus., PMID:37890729

Evaluation and comparison of immune responses induced by two Mpox mRNA vaccine candidates in mice., PMID:37800627

Cross-reactive antibody response to Monkeypox virus surface proteins in a small proportion of individuals with and without Chinese smallpox vaccination history., PMID:37784185

Duration of humoral immunity from smallpox vaccination and its cross-reaction with Mpox virus., PMID:37709783

Mpox vaccine and infection-driven human immune signatures: an immunological analysis of an observational study., PMID:37475115

Recombinant proteins A29L, M1R, A35R, and B6R vaccination protects mice from mpox virus challenge., PMID:37435062

Mpox virus mRNA-lipid nanoparticle vaccine candidates evoke antibody responses and drive protection against the Vaccinia virus challenge in mice., PMID:37429529

Immunogenic proteins and potential delivery platforms for mpox virus vaccine development: A rapid review., PMID:37353117

Multi-valent mRNA vaccines against monkeypox enveloped or mature viron surface antigens demonstrate robust immune response and neutralizing activity., PMID:37300753

Three neutralizing mAbs induced by MPXV A29L protein recognizing different epitopes act synergistically against orthopoxvirus., PMID:37288876

Design peptide and multi-epitope protein vaccine candidates against monkeypox virus using reverse vaccinology approach: an in-silico study., PMID:37154825

Monkeypox virus quadrivalent mRNA vaccine induces immune response and protects against vaccinia virus., PMID:37117161

Rational development of multicomponent mRNA vaccine candidates against mpox., PMID:36947428

BoHV-4-Based Vector Single Heterologous Antigen Delivery Protects STAT1(-/-) Mice from Monkeypoxvirus Lethal Challenge., PMID:26086739

Datasheet
$ 480
Product specifications
100 μg 480 1 mg 2880

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Recombinant Monkeypox virus/MPXV A29L Protein, C-His [EVV13401]
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