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Anti-Human CD24 Antibody (SWA11)

Catalog #:   FHD65210 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: FCM, IHC, IF, RIA
Accession: P25063
Overview

Catalog No.

FHD65210

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

Unconjugated

Target

Signal transducer CD24, CD24, CD24A, Small cell lung carcinoma cluster 4 antigen

Concentration

3.3 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P25063

Applications

FCM, IHC, IF, RIA

Form

Liquid

Storage buffer

100 mM Pro-Ac, 20 mM Arg, pH 5.0

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SWA11

Data Image
  • Flow-cytometry
    Flow-cytometry using anti- human CD24 antibody. Human SK-BR-3 cell line were stained with an irrelevant antibody (Green Histogram) or an anti- human CD24 antibody monoclonal antibody (Catalog # FHD65210 , Red Histogram) at a concentration of 20 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # PMB96441) and cells analysed on a NovoCyte Flow Cytometer.
  • Bioactivity
    Detects CD24 in indirect ELISAs.
References

Peripheral memory B cell population maintenance and long-term survival after perioperative chemoimmunotherapy in NSCLC (NADIM trial)., PMID:40468805

Defective neutrophil clearance in JAK2V617F myeloproliferative neoplasms drives myelofibrosis via immune checkpoint CD24., PMID:40373279

N-deglycosylation targeting chimera (DGlyTAC): a strategy for immune checkpoint proteins inactivation by specifically removing N-glycan., PMID:40289109

CD24-targeted CAR-T cells mediated long-term anti-tumor efficacy through activation of endogenous tumor immune responses., PMID:40105191

Neutrophil extracellular traps impede cancer metastatic seeding via protease-activated receptor 2-mediated downregulation of phagocytic checkpoint CD24., PMID:40010762

Deep profiling of B cells responding to various pathogens uncovers compartments in IgG memory B cell and antibody-secreting lineages., PMID:39970201

ADARp110 promotes hepatocellular carcinoma progression via stabilization of CD24 mRNA., PMID:39808660

Dual-target magneto-immunoassay with bifunctional nanohybrids for breast cancer exosome detection., PMID:39788070

CD47 predominates over CD24 as a macrophage immune checkpoint in cancer., PMID:39651307

PPAB001, a novel bispecific antibody against CD47 and CD24, enhances anti-PD-L1 efficacy in triple-negative breast cancer via reprogramming tumor-associated macrophages towards M1 phenotype., PMID:39622130

Identification of the central tolerance checkpoint for autoreactive proteinase 3+ B cells in human bone marrow., PMID:39549483

Is modulation of immune checkpoints on glioblastoma-infiltrating myeloid cells a viable therapeutic strategy?, PMID:39427326

Phenotypic Characterization of B-Lymphocyte Subpopulations in Human Peripheral Blood: A Cost-Effective Seven-Color One-Tube Protocol., PMID:39348052

Immune Cell Profiles of Patients with Sickle Cell Disease during Parvovirus B19-Induced Transient Red Cell Aplasia., PMID:39340016

The missing link between cancer stem cells and immunotherapy., PMID:39316769

Sensitive phenotyping of serum extracellular vesicles on a SERS-microfluidic platform for early-stage clinical diagnosis of ovarian carcinoma., PMID:39260102

Human circulating CD24hi marginal zone B cells produce IgM targeting atherogenic antigens and confer protection from vascular disease., PMID:39196097

Evolution of pathologic B-cell subsets and serum environment-specific sIgEs in patients with atopic dermatitis and controls, from infancy to adulthood., PMID:39003573

An in-situ peptide-antibody self-assembly to block CD47 and CD24 signaling enhances macrophage-mediated phagocytosis and anti-tumor immune responses., PMID:38971872

Exosomes multiplex profiling, a promising strategy for early diagnosis of laryngeal cancer., PMID:38902710

Sonocatalytic oncolysis microbiota curb intrinsic microbiota lactate metabolism and blockade CD24-Siglec10 immune escape to revitalize immunological surveillance., PMID:38878482

Increased IgD and CD27 Double Negative (DN) B cell population in pediatric onset autoimmune hepatitis., PMID:38770919

A multifunctional antibody fusion protein 57103 targeting CD24, IL-4R, and αvβ3 for treating cancer and regulating the tumor microenvironment., PMID:38761419

Apoptosis in Postmortal Tissues of Goat Spinal Cords and Survival of Resident Neural Progenitors., PMID:38731901

Site-specific Antibody-Nitric Oxide Conjugate HN02 Possesses Improved Antineoplastic and Safety Properties., PMID:38557756

Peg-IFNα combined with hepatitis B vaccination contributes to HBsAg seroconversion and improved immune function., PMID:38555445

Anti-IL-8 monoclonal antibodies inhibits the autophagic activity and cancer stem cells maintenance within breast cancer tumor microenvironment., PMID:38552109

Checkpoint CD24 function on tumor and immunotherapy., PMID:38487533

The response of CD27+CD38+ plasmablasts, CD24hiCD38hi transitional B cells, CXCR5-ICOS+PD-1+ Tph, Tph2 and Tfh2 subtypes to allergens in children with allergic asthma., PMID:38424520

A highly susceptible hACE2-transgenic mouse model for SARS-CoV-2 research., PMID:38389533

Targeting CD24/Siglec-10 signal pathway for cancer immunotherapy: recent advances and future directions., PMID:38279998

In vitro B cell experiments explore the role of CD24, CD38, and energy metabolism in ME/CFS., PMID:38259473

Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth., PMID:38242888

Targeting CD24 in Cancer Immunotherapy., PMID:38137380

FLAER as a standalone reagent for paroxysmal nocturnal hemoglobinuria: Do we need to reconsider the guidelines for testing?, PMID:38069562

Dual blockade of CD47 and CD24 signaling using a novel bispecific antibody fusion protein enhances macrophage immunotherapy., PMID:38046893

RARγ promotes the invasion and metastasis of thyroid carcinoma by activating the JAK1-STAT3-CD24/MMPs axis., PMID:37897947

Dual antibody-aided mesoporous nanoreactor for H2O2 self-supplying chemodynamic therapy and checkpoint blockade immunotherapy in triple-negative breast cancer., PMID:37875918

IMM47, a humanized monoclonal antibody that targets CD24, exhibits exceptional anti-tumor efficacy by blocking the CD24/Siglec-10 interaction and can be used as monotherapy or in combination with anti-PD1 antibodies for cancer immunotherapy., PMID:37846296

Immunological Responses of Arsenicum album 30CH to Combat COVID-19: Protocol for a Double-Blind, Randomized, Placebo-Controlled Clinical Trial in the Pathanamthitta District of Kerala., PMID:37843912

Cancer stem cells are prevalent in the basal-like 2 and mesenchymal triple-negative breast cancer subtypes in vitro., PMID:37771376

Autoreactive B cells in rheumatoid arthritis include mainly activated CXCR3+ memory B cells and plasmablasts., PMID:37725442

15-color highly sensitive flow cytometry assay for post anti-CD19 targeted therapy (anti-CD19-CAR-T and blinatumomab) measurable residual disease assessment in B-lymphoblastic leukemia/lymphoma: Real-world applicability and challenges., PMID:37706583

Effects of blocking CD24 and CD47 'don't eat me' signals in combination with rituximab in mantle-cell lymphoma and chronic lymphocytic leukaemia., PMID:37654003

Stem cell markers: A guide to neoadjuvant therapy in breast carcinomas., PMID:37530329

Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton., PMID:37524694

Renal Tubular CD24 Upregulation Aggravates Folic Acid Induced Acute Kidney Injury: A Possible Role for T Regulatory Cells Inhibition in Mice., PMID:37511747

New hope for tumor immunotherapy: the macrophage-related "do not eat me" signaling pathway., PMID:37484024

Five-year follow-up of a phase I trial of donor-derived modified immune cell infusion in kidney transplantation., PMID:37483623

CD24 is a novel target of chimeric antigen receptor T cells for the treatment of triple negative breast cancer., PMID:37418008

Datasheet
$ 198
Product specifications
50 μg 198 100 μg 328

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For research use only. Not for human or drug use.

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Anti-Human CD24 Antibody (SWA11) [FHD65210]
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