MUC2 and related bacterial factors: Therapeutic targets for ulcerative colitis. PMID: 34902790
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. PMID: 18806221
Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection. PMID: 16831596
Mucin 2 (MUC2) promoter characterization: an overview. PMID: 30218241
Consequence of distinctive expression of MUC2 in colorectal cancers: How much is actually bad? PMID: 34139275
Muc2 Mucin and Nonmucin Microbiota Confer Distinct Innate Host Defense in Disease Susceptibility and Colonic Injury. PMID: 32659381
Prognostic Value of MUC2 Expression in Colorectal Cancer: A Systematic Review and Meta-Analysis. PMID: 29967641
Rare minisatellite alleles of MUC2-MS8 influence susceptibility to rectal carcinoma. PMID: 34436741
DOCK4 stimulates MUC2 production through its effect on goblet cell differentiation. PMID: 33559155
The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions. PMID: 20615996
Somatostatin stimulates colonic MUC2 expression through SSTR5-Notch-Hes1 signaling pathway. PMID: 31733832
The role of MUC2 mucin in intestinal homeostasis and the impact of dietary components on MUC2 expression. PMID: 32707285
Upregulated MUC2 Is an Unfavorable Prognostic Indicator for Rectal Cancer Patients Undergoing Preoperative CCRT. PMID: 34300195
Mucin 2 (MUC2) modulates the aggressiveness of breast cancer. PMID: 30317423
The MUC2 gene product: a human intestinal mucin. PMID: 9722984
Significance of MUC2 gene methylation detection in pancreatic cancer diagnosis. PMID: 31590960
Increased Listeria monocytogenes Dissemination and Altered Population Dynamics in Muc2-Deficient Mice. PMID: 33431704
Association of MUC2, MUC5AC and MUC5B genes with the recurrence of nasal polyps. PMID: 32742413
MUC1 and MUC2 in pancreatic neoplasia. PMID: 15113850
Autophagy is required during high MUC2 mucin biosynthesis in colonic goblet cells to contend metabolic stress. PMID: 34494458
Exogenous NAD+ Stimulates MUC2 Expression in LS 174T Goblet Cells via the PLC-Delta/PTGES/PKC-Delta/ERK/CREB Signaling Pathway. PMID: 32283838
Prognostic significance of MUC2, CDX2 and SOX2 in stage II colorectal cancer patients. PMID: 33823840
Melatonin restores Muc2 depletion induced by V. vulnificus VvpM via melatonin receptor 2 coupling with G伪q. PMID: 31906951
Roles of the gel-forming MUC2 mucin and its O-glycosylation in the protection against colitis and colorectal cancer. PMID: 23037153
Low expression of MUC2 is associated with longer disease-free survival in patients with colorectal carcinoma. PMID: 30226481
Characterization of the regulatory 5'-flanking region of bovine mucin 2 (MUC2) gene. PMID: 33730299
Fucose Ameliorates Tritrichomonas sp.-Associated Illness in Antibiotic-Treated Muc2-/- Mice. PMID: 34639039
Effect of Promoter Methylation on the Expression of Porcine MUC2 Gene and Resistance to PEDV Infection. PMID: 33996974
The Muc2 mucin coats murine Paneth cell granules and facilitates their content release and dispersion. PMID: 29698056
Expression profiles of MUC1, MUC2, and MUC4 mucins in human neoplasms and their relationship with biological behavior. PMID: 18651706
Immunohistochemical study of MUC1, MUC2 and MUC5AC in colorectal carcinoma and review of literature. PMID: 25731647
High MUC2 Mucin Expression and Misfolding Induce Cellular Stress, Reactive Oxygen Production, and Apoptosis in Goblet Cells. PMID: 29545196
CDX2 and Muc2 immunohistochemistry as prognostic markers in stage II colon cancer. PMID: 31121192
The Dynamic Changes of Gut Microbiota in Muc2 Deficient Mice. PMID: 30231491
Colonic MUC2 mucin regulates the expression and antimicrobial activity of 尾-defensin 2. PMID: 25921338
The Reduction-insensitive Bonds of the MUC2 Mucin Are Isopeptide Bonds. PMID: 27129250
MUC2 mucin deficiency alters inflammatory and metabolic pathways in the mouse intestinal mucosa. PMID: 29069719
Decreased expression of MUC2 due to a decrease in the expression of lectins and apoptotic defects in colitis patients. PMID: 31198858
MUC2 Mucin and Butyrate Contribute to the Synthesis of the Antimicrobial Peptide Cathelicidin in Response to Entamoeba histolytica- and Dextran Sodium Sulfate-Induced Colitis. PMID: 28069814
EXPRESSION OF MUC2 GLYCOPROTEIN ANTIBODY AND VASCULAR ENDOTHELIAL GROWTH FACTOR IN BARRETT'S MUCOSA. PMID: 31363321
High MUC2 Mucin Biosynthesis in Goblet Cells Impedes Restitution and Wound Healing by Elevating Endoplasmic Reticulum Stress and Altered Production of Growth Factors. PMID: 29935164
MUC2 gene promoter methylation in mucinous and non-mucinous colorectal cancer tissues. PMID: 20198318
Combined EsophaCap cytology and MUC2 immunohistochemistry for screening of intestinal metaplasia, dysplasia and carcinoma. PMID: 31190949
MUC2 gene expression is found in noninvasive tumors but not in invasive tumors of the pancreas and liver: its close relationship with prognosis of the patients. PMID: 9042800
Investigating the Relationship Between the Expression Level of Mucin Gene Cluster (MUC2, MUC5A, and MUC5B) and Clinicopathological Characterization of Colorectal Cancer. PMID: 35572847
Intestinal Muc2 mucin O-glycosylation is affected by microbiota and regulated by differential expression of glycosyltranferases. PMID: 28122822
Leptin, MUC2 and mTOR in appendiceal mucinous neoplasms. PMID: 22236547
Associations between the expression of mucins (MUC1, MUC2, MUC5AC and MUC6) and clinicopathologic parameters of human breast carcinomas. PMID: 33154304
Immunohistochemical Study of MUC1, MUC2 and MUC5AC Expression in Primary Breast Carcinoma. PMID: 28571146
MUC2 and MUC6 apomucins expression in human gastric neoplasm: an immunohistochemical analysis. PMID: 20878553
MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance. PMID: 27298226
Intestinal MUC2 mucin supramolecular topology by packing and release resting on D3 domain assembly. PMID: 24816392
Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa. PMID: 20485566
Immunohistochemical expression profiles of MUC1 and MUC2 mucins in urothelial tumors of bladder. PMID: 30004053
MUC2 Expression Is Correlated with Tumor Differentiation and Inhibits Tumor Invasion in Gastric Carcinomas: A Systematic Review and Meta-analysis. PMID: 26018517
MUC2 is a molecular marker for pseudomyxoma peritonei. PMID: 12218214
Oxyresveratrol Induces Autophagy via the ER Stress Signaling Pathway, and Oxyresveratrol-Induced Autophagy Stimulates MUC2 Synthesis in Human Goblet Cells. PMID: 32150901
Identifying transglutaminase reaction products via mass spectrometry as exemplified by the MUC2 mucin - Pitfalls and traps. PMID: 32222540
MUC2 is a highly specific marker of goblet cell metaplasia in the distal esophagus and gastroesophageal junction. PMID: 21602660
MUC2 expression is regulated by histone H3 modification and DNA methylation in pancreatic cancer. PMID: 16721789
MUC2 polymorphisms are associated with endometriosis development and infertility: a case-control study. PMID: 22417007
Small intestinal MUC2 synthesis in human preterm infants. PMID: 19246635
MUC2 expression is an adverse prognostic factor in superficial gastroesophageal adenocarcinomas. PMID: 24290360
Mucin Muc2 deficiency and weaning influences the expression of the innate defense genes Reg3尾, Reg3纬 and angiogenin-4. PMID: 22723890
MUC2 is the prominent colonic mucin expressed in ulcerative colitis. PMID: 8707087
Entamoeba histolytica Alters Ileal Paneth Cell Functions in Intact and Muc2 Mucin Deficiency. PMID: 29685982
MUC2 expression in primary mucinous and nonmucinous adenocarcinoma of the prostate: an analysis of 50 cases on radical prostatectomy. PMID: 18487999
Differential Muc2 and Muc5ac secretion by stimulated guinea pig tracheal epithelial cells in vitro. PMID: 16504136
MUC2 expression and prevalence of high-grade dysplasia and invasive carcinoma in mixed-type intraductal papillary mucinous neoplasm of the pancreas. PMID: 24280573
MUC2 but not MUC5 expression correlates with prognosis in radically resected pancreatic cancer patients. PMID: 19587537
The silence of MUC2 mRNA induced by promoter hypermethylation associated with HBV in Hepatocellular Carcinoma. PMID: 23347460
Bile acid induces MUC2 expression and inhibits tumor invasion in gastric carcinomas. PMID: 25475007
Expression of MUC2 in gastric carcinomas and background mucosae. PMID: 17559374
Exopolysaccharides from Lactobacillus plantarum NCU116 Enhances Colonic Mucosal Homeostasis by Controlling Epithelial Cell Differentiation and c-Jun/Muc2 Signaling. PMID: 31407897
Defining cooperative roles for colonic microbiota and Muc2 mucin in mediating innate host defense against Entamoeba histolytica. PMID: 30500860
High MUC2 expression in ovarian cancer is inversely associated with the M1/M2 ratio of tumor-associated macrophages and patient survival time. PMID: 24324582
Intestinal MUC2 and gastric M1/MUC5AC in preneoplastic lesions induced by 1,2-dimethylhydrazine in rat: a sequential analysis. PMID: 17203232
Expression of Pla2g2a prevents carcinogenesis in Muc2-deficient mice. PMID: 19037975
[Another sight at Gastric Cancer Molecular Classification: novel subtypes based on expression of CDX-2, E-cadherin, Epstein-Barr virus RNAs, MMR proteins]., PMID:40531557
D-Tagatose attenuates DSS-induced ulcerative colitis by inhibiting inflammation, reducing intestinal barrier damage and modulating the intestinal flora composition., PMID:40528436
Lactiplantibacillus Plantarum strengthens the intestinal barrier: involvement of the endocannabinoidome., PMID:40522902
Melatonin Mitigates Sarcopenic Obesity via Microbiota and Short-Chain Fatty Acids: Evidence From Epidemiologic and In Vivo Studies., PMID:40511533
Vat-Mediated Mucus Penetration Enables Genotoxic Activity of pks+ Escherichia coli., PMID:40508162
Wuda Granule Alleviates DSS-Induced Colitis in Mice by Inhibiting Inflammation, Protecting Intestinal Barrier and Reducing Oxidative Stress Through Nrf2/Keap1/HO-1 Pathway., PMID:40503489
Plasmon-activated water enhances gut-barrier function and alleviates inflammation in a mouse model of ulcerative colitis., PMID:40496763
High doses of the galactooligosaccharides, 2'-fucosyllactose alleviate immunodeficiency in vitro and in vivo., PMID:40488907
Arabinoxylan from barley bran alleviates ulcerative colitis in mice through enhancement of mucosal barrier function and modulation of gut microbiota., PMID:40480573
Investigation of competitive binding of the essential trace elements zinc, iron, copper and manganese by gastrointestinal mucins and the effect on their absorption in vitro., PMID:40472908
Stimbiotics help improve intestinal immunity and positively modulate the gut microbiome in broilers with necrotic enteritis., PMID:40466265
Effect of selenium nanoparticles on intestinal immunity through regulation of NLRP3 signaling pathway., PMID:40461600
Effects of red ginseng extract and red ginseng dietary fiber on the maintenance of intestinal immune and functional homeostasis in diet-induced obese mice., PMID:40453347
miR166u -enriched Polygonatum sibiricum exosome-like nanoparticles alleviate colitis by improving intestinal barrier through the TLR4/AKT pathway., PMID:40451355
Impact of Enterococcus faecium AL41 on growth performance, immune parameters, morphology, and tight junction proteins in intestine of chicks., PMID:40451071
Structural characteristics of Phaeodactylum tricornutum polysaccharides and the effects on DSS-induced colitis via improving the intestinal barrier and modulating the gut microbiota., PMID:40441573
Evaluation of Indigo Naturalis Prepared Using a Novel Method: Therapeutic Effects on Experimental Ulcerative Colitis in Mice., PMID:40430964
[Effects of donor T cell stat3 deficiency on acute intestinal graft-versus-host disease in mice]., PMID:40425451
Screening of Fecal Bacteroides Strains and Discovery of Bacteroides eggerthii S13-F8 with Protective Effects Against Chemotherapy-Induced Diarrhea., PMID:40423879
Poria cocos polysaccharides ameliorate AOM/DSS-induced colorectal cancer in mice by remodeling intestinal microbiota composition and enhancing intestinal barrier function., PMID:40419041
The effect of anthocyanin extract from Lycium ruthenicum Murray on intestinal barrier function in Bamei ternary pigs., PMID:40410595
Dietary supplementation with antibacterial peptide microcin J25 improved antioxidant capacity and intestinal health of pigeons., PMID:40351762
Thymol promotes cell proliferation and protects against LPS-induced intestinal inflammation via activation of the EGFR/PI3K pathway., PMID:40351714
Tibetan Tea Alleviates the Intestinal Dysfunction in Sleep-Deprived Mice Through Regulating Oxidative Stress and Inflammation-Related Intestinal Metabolisms., PMID:40350986
[Angelicae Dahuricae Radix polysaccharides treat ulcerative colitis in mice by regulating gut microbiota and metabolism]., PMID:40350809
[Mechanism of Xiangmei Pills in treating ulcerative colitis based on UHPLC-Q-Orbitrap HRMS and 16S rDNA sequencing of intestinal flora]., PMID:40350808
Bifidobacterium longum BL300 alleviates DSS-induced Colitis by promoting IgA-mediated Gut Microbiota homeostasis., PMID:40350789
Caffeine plays a prevention role in stress-induced depression by modulating gut-brain axis function., PMID:40348324
Effects of Lactobacillus plantarum-loaded W1/O/W2 emulsions stabilized by ultrasonically treated pea protein on DSS-induced colitis in mice., PMID:40348251
Administration of EPA improves lipopolysaccharide-induced intestinal dysfunction in turbot (Scophthalmus maximus L.) through modulation of TORC1 signaling., PMID:40345275
Faecal mucoprotein MUC2 is decreased in multiple sclerosis and is associated with mucin degrading bacteria., PMID:40344717
Enteromorpha prolifera soluble dietary fiber alleviates ulcerative colitis through restoration of mucosal barrier and gut microbiota homeostasis., PMID:40342374
Studies on the changes in rectal permeability and intestinal microbiota with developmental age in young rats., PMID:40336831
The role of macrophage polarization in ovarian cancer: from molecular mechanism to therapeutic potentials., PMID:40330466
Tea residue protein-derived oligopeptides attenuate DSS-induced acute colitis complicated with hepatic injury in C57BL/6J mice by regulating the gut-microbiome-liver axis., PMID:40311592
Synergistic effect of 2'-fucosyllactose and osteopontin on intestinal mucosal immunity injury., PMID:40308162
Bioactive chitosan-BSA Maillard-derived chrysin-loaded nanoparticles: A gastroprotective, biomucoadhesive approach for enhanced oral therapy in ulcerative colitis., PMID:40306769
The Role of Lactiplantibacillus plantarum CGMCC9513 in Alleviating Colitis by Synergistic Enhancement of the Intestinal Barrier Through Modulating Gut Microbiota and Activating the Aryl Hydrocarbon Receptor., PMID:40301232
Effects of Lactic Acid and Glyceryl Lactate on Growth Performance, Antioxidant Capacity, and Intestinal Health of Piglets., PMID:40298648
MCT4 inhibition attenuates inflammatory response to Mycobacterium avium paratuberculosis infection and restores intestinal epithelial integrity in vitro., PMID:40297589
Exogenous acetate mitigates later enhanced allergic airway inflammation in a menopausal mouse model., PMID:40292217
Growth Performance, Immuno-Oxidant Status, Intestinal Health, Gene Expression, and Histomorphology of Growing Quails Fed Diets Supplemented with Essential Oils and Probiotics., PMID:40284844
Exposure of broiler chickens to deoxynivalenol and Campylobacter jejuni induces substantial changes in intestinal gene expression., PMID:40253521
Nondigestible stachyose alleviates cyclophosphamide-induced small intestinal mucosal injury in mice by regulating intestinal exosomal miRNAs, independently of the gut microbiota., PMID:40253186
Family adenomatous polyposis come across dome type adenocarcinoma: a case report and literature review., PMID:40247408
Protective Effects of a Polyherbal Mixture on Intestinal Injury via the NF-κB Signaling Pathway and Gut Microbiota Modulation in Hyperuricemic Mice., PMID:40238278
Six Weeks of Moderate-Intensity Treadmill Exercise Improves Intestinal Barrier and Intestinal Inflammation in Parkinson's Disease Mice., PMID:40232644
Elucidation of the mechanism of carcinogenic transformation of human gastric epithelial cells in atrophic gastritis., PMID:40220876
Absorption and transport of polysaccharides from soybean seed coat in the Caco-2 cell model and their interaction with the MUC2 protein., PMID:40220811
Identification and Validation of Cyclic Peptides with Mucin-Selective, Location-Specific Binding in the Gastrointestinal Tract., PMID:40216380