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Anti-CD160 Polyclonal Antibody

Catalog #:   PHB80801 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: O95971
Overview

Catalog No.

PHB80801

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD160 (Gly37-Asn154).

Applications

ELISA, IHC, WB

Recommended Dilution

Application Dilution
ELISA 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Natural killer cell receptor BY55,CD160 antigen,CD160,BY55

Purification

Purified by antigen affinity column.

Accession

O95971

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Note

For research use only.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CD160 antibody (PHB80801) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 16 kDa
    Observed MW: 16 kDa
References

Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-γ-producing cells., PMID:23453631

CD160Ig fusion protein targets a novel costimulatory pathway and prolongs allograft survival., PMID:23593209

Rapid perturbation in viremia levels drives increases in functional avidity of HIV-specific CD8 T cells., PMID:23853580

Liver environment and HCV replication affect human T-cell phenotype and expression of inhibitory receptors., PMID:24148617

PD-1 blockade in chronically HIV-1-infected humanized mice suppresses viral loads., PMID:24204962

CD8 T cell memory to a viral pathogen requires trans cosignaling between HVEM and BTLA., PMID:24205056

[CD160 characterization and its association with disease progression in patients with chronic HIV-1 infection]., PMID:25146744

CD160 isoforms and regulation of CD4 and CD8 T-cell responses., PMID:25179432

Interleukin-22 and CD160 play additive roles in the host mucosal response to Clostridium difficile infection in mice., PMID:25327211

Genes associated with antibody-dependent cell activation are overexpressed in renal biopsies from patients with antibody-mediated rejection., PMID:25449536

T cells Exhibit Reduced Signal Transducer and Activator of Transcription 5 Phosphorylation and Upregulated Coinhibitory Molecule Expression After Kidney Transplantation., PMID:25769075

Immune checkpoint protein inhibition for cancer: preclinical justification for CTLA-4 and PD-1 blockade and new combinations., PMID:25965355

Increased Heterologous Protein Expression in Drosophila S2 Cells for Massive Production of Immune Ligands/Receptors and Structural Analysis of Human HVEM., PMID:26202493

Specific CD8(+) T cell response immunotherapy for hepatocellular carcinoma and viral hepatitis., PMID:27605882

Modulation of cytotoxic responses by targeting CD160 prolongs skin graft survival across major histocompatibility class I barrier., PMID:27702550

Evidence for CD16a-Mediated NK Cell Stimulation in Antibody-Mediated Kidney Transplant Rejection., PMID:27906829

PD-1 Blockade Promotes Emerging Checkpoint Inhibitors in Enhancing T Cell Responses to Allogeneic Dendritic Cells., PMID:28588576

Mechanistic Sharing Between NK Cells in ABMR and Effector T Cells in TCMR., PMID:28654216

Antibodies targeting BTLA or TIM-3 enhance HIV-1 specific T cell responses in combination with PD-1 blockade., PMID:28882621

A herpesvirus entry mediator mutein with selective agonist action for the inhibitory receptor B and T lymphocyte attenuator., PMID:29061848

Associations between HVEM/LIGHT/BTLA/CD160 polymorphisms and the occurrence of antibody-mediate rejection in renal transplant recipients., PMID:29245962

ADCC-Mediated CD56DIM NK Cell Responses Are Associated with Early HBsAg Clearance in Acute HBV Infection., PMID:29541698

Anti-CD160, Alone or in Combination With Bevacizumab, Is a Potent Inhibitor of Ocular Neovascularization in Rabbit and Monkey Models., PMID:29860455

Ox40 regulates the conversion and suppressive function of double-negative regulatory T cells., PMID:30268799

[A Preliminary Study on the Expression of CD160 on NK Cells and Its Mechanism of Mediating NK Killing Effect]., PMID:30295284

Monocytes of Different Subsets in Complexes with Platelets in Patients with Myocardial Infarction., PMID:30300910

Soluble Fc-Disabled Herpes Virus Entry Mediator Augments Activation and Cytotoxicity of NK Cells by Promoting Cross-Talk between NK Cells and Monocytes., PMID:30770415

CD19-targeting fusion protein combined with PD1 antibody enhances anti-tumor immunity in mouse models., PMID:32363119

A primer set for the rapid isolation of scFv fragments against cell surface antigens from immunised rats., PMID:33154441

Combining phage display with SMRTbell next-generation sequencing for the rapid discovery of functional scFv fragments., PMID:33382949

A proportion of CD4+ T cells from patients with chronic Chagas disease undergo a dysfunctional process, which is partially reversed by benznidazole treatment., PMID:33539379

Distinct Molecular Subtypes of Diffuse Large B Cell Lymphoma Patients Treated with Rituximab-CHOP Are Associated with Different Clinical Outcomes and Molecular Mechanisms., PMID:34250086

A novel 10-gene immune-related lncRNA signature model for the prognosis of colorectal cancer., PMID:34814366

Disruption of Cell-Cell Communication in Anaplastic Thyroid Cancer as an Immunotherapeutic Opportunity., PMID:34888843

Interacting Genetic Lesions of Melanoma in the Tumor Microenvironment: Defining a Viable Therapy., PMID:34888847

Attenuation of the BTLA/HVEM Regulatory Network in the Circulation in Primary Sjögren's Syndrome., PMID:35159987

Expression Profile and Biological Role of Immune Checkpoints in Disease Progression of HIV/SIV Infection., PMID:35336991

Changes in the natural killer cell repertoire and function induced by the cancer immune adjuvant candidate IMMUNEPOTENT-CRP., PMID:35381435

The soluble form of CD160 acts as a tumor mediator of immune escape in melanoma., PMID:35428910

Immune features of COVID-19 convalescent individuals revealed by a single-cell RNA sequencing., PMID:35453072

Realigning the LIGHT signaling network to control dysregulated inflammation., PMID:35604387

BTLA inhibition has a dominant role in the cis-complex of BTLA and HVEM., PMID:36081508

Interleukin-21 promotes Type-1 activation and cytotoxicity of CD56dimCD16bright natural killer cells during kidney allograft antibody-mediated rejection showing a new link between adaptive and innate humoral allo-immunity., PMID:37220805

Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors., PMID:37230538

Beyond CTLA-4 and PD-1 Inhibition: Novel Immune Checkpoint Molecules for Melanoma Treatment., PMID:37345056

Beyond the anti-PD-1/PD-L1 era: promising role of the BTLA/HVEM axis as a future target for cancer immunotherapy., PMID:37649037

Linking donor-specific antibody generation with natural killer cells in antibody-mediated kidney graft rejection., PMID:37739612

Combination of oligo-fractionated irradiation with nivolumab can induce immune modulation in gastric cancer., PMID:38290769

Identification of CD160-TM as a tumor target on triple negative breast cancers: possible therapeutic applications., PMID:38360636

Ex vivo sensitivity to broadly neutralizing antibodies and anti-CD4 antibody UB-421 of infectious viral isolates from people living with multidrug-resistant HIV., PMID:38728839

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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Distributor list

For research use only. Not for human or drug use.

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Anti-CD160 Polyclonal Antibody [PHB80801]
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