Catalog No.
EHH39201
Expression system
Insect Cells
Species
Homo sapiens (Human)
Protein length
Gly27-Asn763
Predicted molecular weight
84.75 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16853
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Membrane primary amine oxidase, AOC3, SSAO, Semicarbazide-sensitive amine oxidase, Vascular adhesion protein 1, VAP-1, HPAO, Copper amine oxidase, VAP1
Screening and identification of novel protein markers of early-stage lung cancer and construction and application of screening models., PMID:40496615
Therapeutic Potential of Vascular Adhesion Protein-1 (VAP-1)/Semicarbazide-Sensitive Amine Oxidase (SSAO) Inhibitors: Current Medicinal Chemistry and Emerging Opportunities., PMID:40396328
Targeting vascular adhesion protein-1 and myeloperoxidase with a dual inhibitor SNT-8370 in preclinical models of inflammatory disease., PMID:40210617
Serum Biomarkers in Thyroid Malignancies: Evaluating Thyroid-Stimulating Hormone Receptor (TSHR) and Vascular Adhesion Protein-1 (VAP-1) as Potential Diagnostic Biomarker., PMID:40156417
Proteomic analysis of premature umbilical cord blood and its relationship with bronchopulmonary dysplasia., PMID:40098026
Ectopic Overexpression of Rapeseed BnaNTL1 Transcription Factor Positively Regulates Plant Resistance to Sclerotinia sclerotiorum through Modulating JA Synthesis and ROS Accumulation., PMID:39979321
Precision medicine in diabetes prediction: Exploring a subgroup-specific biomarker strategy for risk stratification., PMID:39535373
Elucidating the roles of SOD3 correlated genes and reactive oxygen species in rare human diseases using a bioinformatic-ontology approach., PMID:39480826
Unveils key proteins in Xinjiang goat muscle linked to post-mortem meat quality: A TMT-based proteomic analysis., PMID:39398871
AOC3 accelerates lung metastasis of osteosarcoma by recruiting tumor-associated neutrophils, neutrophil extracellular trap formation and tumor vascularization., PMID:39296147
Vascular-adhesion protein 1 in giant cell arteritis and polymyalgia rheumatica., PMID:39206172
Amine Oxidase, Copper Containing 3 (Aoc3) Knockout Mice Are More Prone to DSS-induced Colitis and Colonic Tumorigenesis., PMID:39187313
Serum Vascular Adhesion Protein-1 and Endothelial Dysfunction in Hepatic Cirrhosis: Searching for New Prognostic Markers., PMID:39000418
Expression of amine oxidase-related proteins in breast phyllodes tumor., PMID:38887035
Combining metabolomics with network pharmacology to reveal the therapeutic mechanism of Dingchuan Decoction in rats with OVA-induced allergic asthma., PMID:38850849
Vascular adhesion protein-1 blockade in primary sclerosing cholangitis: Open-label, multicenter, single-arm, phase II trial., PMID:38668724
The role of vascular adhesion protein-1 in diabetes and diabetic complications., PMID:38581224
Crosstalk of cell death pathways unveils an autophagy-related gene AOC3 as a critical prognostic marker in colorectal cancer., PMID:38461356
LINC01936 inhibits the proliferation and metastasis of lung squamous cell carcinoma probably by EMT signaling and immune infiltration., PMID:38084139
Sepsis induced cardiotoxicity by promoting cardiomyocyte cuproptosis., PMID:38006800
A randomised Phase IIa trial of amine oxidase copper-containing 3 (AOC3) inhibitor BI 1467335 in adults with non-alcoholic steatohepatitis., PMID:37932258
4D DIA-PRM proteomic study identifying modulated pathways and biomarkers associated with pelvic organ prolapse., PMID:37922782
Quantitative serum proteome analysis using tandem mass tags in dogs with epilepsy., PMID:37879566
Construction of Prognostic Model and miRNA-mRNA Regulatory Network for Lung Squamous Cell Carcinoma., PMID:37856813
Identification of AOC3 and LRRC17 as Colonic Fibroblast Activation Markers and Their Potential Roles in Colorectal Cancer Progression., PMID:37774061
Transcriptomics integrated with metabolomics reveals perfluorobutane sulfonate (PFBS) exposure effect during pregnancy and lactation on lipid metabolism in rat offspring., PMID:37696479
Expression of Amine Oxidase Proteins in Adrenal Cortical Neoplasm and Pheochromocytoma., PMID:37509535
Soluble Vascular Adhesion Protein 1 (sVAP-1) as a biomarker for pregnancy complications: A pilot study., PMID:37253043
Identification and validation of hub genes in drug induced acute kidney injury basing on integrated transcriptomic analysis., PMID:37063876
Amine oxidase copper-containing 3 aggravates cardiac remodelling by generating hydrogen peroxide after myocardial infarction., PMID:36825552
Whole genome sequencing revealed genetic diversity, population structure, and selective signature of Panou Tibetan sheep., PMID:36707771
Semicarbazide-Sensitive Amine Oxidase (SSAO) and Lysyl Oxidase (LOX) Association in Rat Aortic Vascular Smooth Muscle Cells., PMID:36358914
Vascular adhesion protein-1 expression is reduced in the intestines of infants with necrotizing enterocolitis: an observational research study., PMID:36335313
Vascular adhesion protein-1 (VAP-1) in vascular inflammatory diseases., PMID:36200383
A novel immune cell signature for predicting osteosarcoma prognosis and guiding therapy., PMID:36189307
Increased atherosclerotic plaque in AOC3 knock-out in ApoE-/- mice and characterization of AOC3 in atherosclerotic human coronary arteries., PMID:36176983
ω-(5-Phenyl-2H-tetrazol-2-yl)alkyl-substituted hydrazides and related compounds as inhibitors of amine oxidase copper containing 3 (AOC3)., PMID:35507758
Transcriptomic and Metabolomic Analyses Reveal Key Metabolites, Pathways and Candidate Genes in Sophora davidii (Franch.) Skeels Seedlings Under Drought Stress., PMID:35310664
Soluble Vascular Adhesion Protein-1 Level Correlates With Adropin and Inflammatory Biomarkers in Patients With Obstructive Sleep Apnea., PMID:35261273
Vascular adhesion protein-1 and microvascular diabetic complications., PMID:35001320
Endothelial cell-derived SSAO can increase MLC20 phosphorylation in VSMCs., PMID:34722886
Amine oxidase, copper containing 3 exerts anti‑mesenchymal transformation and enhances CD4+ T‑cell recruitment to prolong survival in lung cancer., PMID:34318901
BET inhibitor suppresses migration of human hepatocellular carcinoma by inhibiting SMARCA4., PMID:34083693
Environmental and Genetic Factors in the Pathogenesis of COPD in the Road-Working Population., PMID:34012494
Amine oxidase copper-containing 3 (AOC3) inhibition: a potential novel target for the management of diabetic retinopathy., PMID:33845913
SSAO/VAP-1 in Cerebrovascular Disorders: A Potential Therapeutic Target for Stroke and Alzheimer's Disease., PMID:33805974
NG2/CSPG4, CD146/MCAM and VAP1/AOC3 are regulated by myocardin-related transcription factors in smooth muscle cells., PMID:33727640
Protective effects of the novel amine-oxidase inhibitor multi-target drug SZV 1287 on streptozotocin-induced beta cell damage and diabetic complications in rats., PMID:33338750
Inhibition of vascular adhesion protein-1 modifies hepatic steatosis in vitro and in vivo., PMID:33312420
Carotid imaging changes and serum IL-1β, sICAM-1, and sVAP-1 levels in benign paroxysmal positional vertigo., PMID:33299063
For research use only. Not for human or drug use.
