Research Grade Anti-Human F8 (TB-402)

Catalog No.

DHB86201

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Target

AHF, Procoagulant component, Coagulation factor VIII, Antihemophilic factor, F8C, F8

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P00451

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

TB-402, TB 402, TB402

Clone ID

TB-402

TB-402 for the prevention of venous thromboembolism in orthopaedic surgery: something new and promising, or not?, PMID:23677042

Single-dose TB-402 or rivaroxaban for the prevention of venous thromboembolism after total hip replacement. A randomised, controlled trial., PMID:23615791

Antidote strategies to reverse anticoagulation with TB-402, a long-acting partial inhibitor of factor VIII., PMID:22540161

Partial versus complete factor VIII inhibition in a mouse model of venous thrombosis., PMID:21777952

Single intravenous administration of TB-402 for the prophylaxis of venous thromboembolism after total knee replacement: a dose-escalating, randomized, controlled trial., PMID:21284801

New parenteral anticoagulants in development., PMID:21045018

Tolerability and pharmacokinetics of TB-402 in healthy male volunteers., PMID:20637972

Document Download

Research Grade Anti-Human F8 (TB-402).pdf