Research Grade Anti-Human CD40/TNFRSF5 (2141-V11)

Catalog No.

DHD68929

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Target

Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, TNFRSF5, CDw40, CD40

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P25942

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

2141-V11, 2141 V11, 2141V11

Clone ID

2141-V11

Intratumoral Fc-optimized agonistic CD40 antibody induces tumor rejection and systemic antitumor immunity in patients with metastatic cancer., PMID:38883779

Harnessing the potential of CD40 agonism in cancer therapy., PMID:38102001

IL-15 synergizes with CD40 agonist antibodies to induce durable immunity against bladder cancer., PMID:37607227

IL-15 synergizes with CD40 agonist antibodies to induce durable immunity against bladder cancer., PMID:36778311

Dendritic cell targeting with Fc-enhanced CD40 antibody agonists induces durable antitumor immunity in humanized mouse models of bladder cancer., PMID:34011627

Document Download

Research Grade Anti-Human CD40/TNFRSF5 (2141-V11).pdf