Catalog No.
PAH02202
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
Nivolumab
Tested applications
ELISA: 1:4000-1:8000
Target
Rabbit polyclonal to Opdivo.
Specificity
The product is specific for Nivolumab. This antibody serves as an excellent positive control for Nivolumab immunogenicity (ADA) assays.
Concentration
0.5 mg/ml
Purification
Purified by antigen affinity column.
Accession
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
Background
Nivolumab (Opdivo) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Nivolumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. Antibodysystem Anti-Nivolumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Nivolumab.
For research use only. Not for human or drug use.
