Catalog No.
PAD17201
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
Ipilimumab
Tested applications
ELISA: 1:4000-1:8000
Target
Rabbit polyclonal to Yervoy.
Specificity
The product is specific for Ipilimumab. This antibody serves as an excellent positive control for Ipilimumab immunogenicity (ADA) assays.
Concentration
0.27 mg/ml
Purification
Purified by antigen affinity column.
Accession
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
Background
Ipilimumab (Yervoy) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Ipilimumab works to activate the immune system by targeting CTLA-4 (Cytotoxic T-lymphocyte protein 4), a negative regulator of cytotoxic T-lymphocyte activity. Ipilimumab binds to CTLA-4, blocking the inhibitory signal, which allows the cytotoxic T-lymphocytes to destroy the cancer cells.
For research use only. Not for human or drug use.
