Catalog No.
PAC36902
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
Tocilizumab
Tested applications
ELISA: 1:4000-1:8000
Target
Rabbit polyclonal to Actemra.
Specificity
The product is specific for Tocilizumab. This antibody serves as an excellent positive control for Tocilizumab immunogenicity (ADA) assays.
Concentration
0.72 mg/ml
Purification
Purified by antigen affinity column.
Accession
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
Background
Tocilizumab (Actemra) is a humanized monoclonal antibody that is developed by Hoffmann–La Roche and Chugai for the treatment of patients with rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children. Tocilizumab binds to the interleukin-6 receptor (IL-6R) and blocks its interaction with interleukin 6 (IL-6), hindering IL-6 from exerting its pro-inflammatory effects.
For research use only. Not for human or drug use.
