Catalog No.
PAA30301
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
Denosumab
Tested applications
ELISA: 1:4000-1:8000
Target
Rabbit polyclonal to Prolia.
Specificity
The product is specific for Denosumab. This antibody serves as an excellent positive control for Denosumab immunogenicity (ADA) assays.
Concentration
0.6 mg/ml
Purification
Purified by antigen affinity column.
Accession
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
Background
Denosumab with trade name Prolia, is an FDA-approved drug for the treatment of patients with osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. Denosumab is a fully human monoclonal antibody that works as a RANK ligand (RANKL) inhibitor. Denosumab can bind RANKL, preventing RANKL from activating RANK, its receptor on the osteoclast surface.
For research use only. Not for human or drug use.
