Research Grade Anti-Human SNCA/Alpha-synuclein (Lu AF82422)

Catalog No.

DHE22008

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG1

Clonality

Monoclonal

Target

Alpha-synuclein, PARK1, Non-A4 component of amyloid precursor, NACP, Non-A beta component of AD amyloid, SNCA

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P37840

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

Lu AF82422

Clone ID

Lu AF82422

Rational selection of the monoclonal α-synuclein antibody amlenetug (Lu AF82422) for the treatment of α-synucleinopathies., PMID:40404755

An update on immune-based alpha-synuclein trials in Parkinson's disease., PMID:39666171

Randomized Phase I Trial of the α-Synuclein Antibody Lu AF82422., PMID:38494847

Nonclinical safety evaluation, pharmacokinetics, and target engagement of Lu AF82422, a monoclonal IgG1 antibody against alpha-synuclein in development for treatment of synucleinopathies., PMID:34709986

Document Download

Research Grade Anti-Human SNCA/Alpha-synuclein (Lu AF82422).pdf