Anti-OGG1 Polyclonal Antibody

Catalog No.

PHA56001

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human OGG1 (Ser31-Gly345).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

OGH1,N-glycosylase/DNA lyase,OGG1,MMH,MUTM,AP lyase

Purification

Purified by antigen affinity column.

Accession

O15527

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Development and characterization of a novel NEIL1 nanobody., PMID:40440929

Dulaglutide reduces oxidative DNA damage and hypermethylation in the somatic cells of mice fed a high-energy diet by restoring redox balance, inflammatory responses, and DNA repair gene expressions., PMID:38963172

USP18 enhances dengue virus replication by regulating mitochondrial DNA release., PMID:37978268

Neuropathological Examination of Mice Chronically Exposed to Secondhand Smoke., PMID:37948264

Differential Binding of NLRP3 to non-oxidized and Ox-mtDNA mediates NLRP3 Inflammasome Activation., PMID:37253813

DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse model., PMID:34186496

Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model., PMID:33072095

Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions., PMID:32555206

Oxidized base 8-oxoguanine, a product of DNA repair processes, contributes to dendritic cell activation., PMID:31408726

Role of metallothionein-like cadmium-binding protein (MTLCdBP) in the protective mechanism against cadmium toxicity in the testis., PMID:30606898

Excision release of 5?hydroxycytosine oxidatively induced DNA base lesions from the lung genome by cat dander extract challenge stimulates allergic airway inflammation., PMID:30244512

Oxidatively generated base modifications in DNA: Not only carcinogenic risk factor but also regulatory mark?, PMID:27871818

Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET)., PMID:27593437

Cell Killing Mechanisms and Impact on Gene Expression by Gemcitabine and 212Pb-Trastuzumab Treatment in a Disseminated i.p. Tumor Model., PMID:27467592

Mitochondrial OGG1 protects against PM2.5-induced oxidative DNA damage in BEAS-2B cells., PMID:26297428

Inflammation and pyroptosis mediate muscle expansion in an interleukin-1β (IL-1β)-dependent manner., PMID:25596528

Altered DNA Methylation and Expression Profiles of 8-Oxoguanine DNA Glycosylase 1 in Lens Tissue from Age-related Cataract Patients., PMID:25310012

Embryonic exposure to carbendazim induces the transcription of genes related to apoptosis, immunotoxicity and endocrine disruption in zebrafish (Danio rerio)., PMID:25304545

Impact of α-targeted radiation therapy on gene expression in a pre-clinical model for disseminated peritoneal disease when combined with paclitaxel., PMID:25268703

The changes of 8-OHdG, hOGG1, APE1 and Pol β in lenses of patients with age-related cataract., PMID:24911554

Hyperactivation of Akt/mTOR and deficiency in tuberin increased the oxidative DNA damage in kidney cancer patients with diabetes., PMID:24797175

Increased 8-hydroxy-2'-deoxyguanosine in plasma and decreased mRNA expression of human 8-oxoguanine DNA glycosylase 1, anti-oxidant enzymes, mitochondrial biogenesis-related proteins and glycolytic enzymes in leucocytes in patients with systemic lupus erythematosus., PMID:24345202

Combined effects of polymorphisms of DNA-repair protein genes and metabolic enzyme genes on the risk of cholangiocarcinoma., PMID:24049014

Oxidative DNA damage in Barrett mucosa: correlation with telomeric dysfunction and p53 mutation., PMID:23744553

Age-dependent guanine oxidation in DNA of different brain regions of Wistar rats and prematurely aging OXYS rats., PMID:23403132

The DNA glycosylases Ogg1 and Nth1 do not contribute to Ig class switching in activated mouse splenic B cells., PMID:22536455

SNPs in DNA repair genes associated to meningitis and host immune response., PMID:21651918

DNA repair enzyme polymorphisms and oxidative stress in a Turkish population with gastric carcinoma., PMID:21390502

Evidence that OGG1 glycosylase protects neurons against oxidative DNA damage and cell death under ischemic conditions., PMID:20736962

Characterization of oxidative guanine damage and repair in mammalian telomeres., PMID:20485567

DNA damages induced by trans, trans-2,4-decadienal (tt-DDE), a component of cooking oil fume, in human bronchial epithelial cells., PMID:20143344

1-Methyl-4-phenyl-pyridinium time-dependently alters expressions of oxoguanine glycosylase 1 and xeroderma pigmentosum group F protein in PC12 cells., PMID:20101267

Deficiency of the oxidative damage-specific DNA glycosylase NEIL1 leads to reduced germinal center B cell expansion., PMID:19782007

Quantitative analysis of oxidized guanine, 8-oxoguanine, in mitochondrial DNA by immunofluorescence method., PMID:19513676

DNA repair polymorphisms and the risk of stomach adenocarcinoma and severe chronic gastritis in the EPIC-EURGAST study., PMID:18641418

Site-directed photoproteolysis of 8-oxoguanine DNA glycosylase 1 (OGG1) by specific porphyrin-protein probe conjugates: a strategy to improve the effectiveness of photodynamic therapy for cancer., PMID:17251034

UVA irradiation induces relocalisation of the DNA repair protein hOGG1 to nuclear speckles., PMID:17148573

OGG1 and MYH are involved in the incision of trivalent arsenical-induced DNA adducts., PMID:17135312

8-Oxoguanine DNA glycosylase and MutY homolog are involved in the incision of arsenite-induced DNA adducts., PMID:17101720

Analysis of Hemicentin-1, hOgg1, and E-selectin single nucleotide polymorphisms in age-related macular degeneration., PMID:17057786

Contrasting genome-wide distribution of 8-hydroxyguanine and acrolein-modified adenine during oxidative stress-induced renal carcinogenesis., PMID:17003489

Oxidative DNA damage in pterygium., PMID:15692461

Cell cycle regulation of the murine 8-oxoguanine DNA glycosylase (mOGG1): mOGG1 associates with microtubules during interphase and mitosis., PMID:15474421

Detection of a smaller, 32-kDa 8-oxoguanine DNA glycosylase 1 in 3'-methyl-4-dimethylamino-azobenzene-treated mouse liver., PMID:14965360

Immunofluorescent localization of the murine 8-oxoguanine DNA glycosylase (mOGG1) in cells growing under normal and nutrient deprivation conditions., PMID:14642563

Normal somatic hypermutation of Ig genes in the absence of 8-hydroxyguanine-DNA glycosylase., PMID:12759433

Reduced constitutive 8-oxoguanine-DNA glycosylase expression and impaired induction following oxidative DNA damage in the tuberin deficient Eker rat., PMID:12663520

Measurement of oxidative damage at individual gene levels by quantitative PCR using 8-hydroxyguanine glycosylase (OGG1)., PMID:12628521

Human OGG1 undergoes serine phosphorylation and associates with the nuclear matrix and mitotic chromatin in vivo., PMID:12034821

Involvement of mammalian OGG1(MMH) in excision of the 8-hydroxyguanine residue in DNA., PMID:11978483

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