Catalog No.
YHD70901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser181
Predicted molecular weight
22.99 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P26441
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CNTF, Ciliary neurotrophic factor
The potential of ciliary neurotrophic factor receptor as a biomarker for urine-based noninvasive diagnosis of prostate cancer., PMID:40493768
Targeting neurotrophic dysregulation in diabetic retinopathy: a novel therapeutic avenue., PMID:40488922
Cognitive function and retinal biomarkers as novel approach to diagnosing and assessing autism spectrum disorder., PMID:40410251
Association of neurobiological and immune serum biomarkers with Toxoplasma gondii infection in patients with schizophrenia., PMID:40397143
Survival and Axonal Regeneration of Retinal Ganglion Cells in a Mouse Optic Nerve Crush Model After a Cell-Based Intravitreal Co-Administration of Ciliary Neurotrophic Factor and Glial Cell Line-Derived Neurotrophic Factor at Different Post-Lesion Time Points., PMID:40358167
Bioinformatics-driven exploration of key genes and mechanisms underlying oxidative stress in traumatic brain injury., PMID:40353060
Impact of COVID-19 vaccination on symptoms and immune phenotypes in vaccine-naïve individuals with Long COVID., PMID:40346201
The Causal Relationship Between Neurotrophic Factors and Delirium: A Mendelian Randomization Study., PMID:40321107
Comparative Analysis of Primary Sarcopenia and End-Stage Renal Disease-Related Muscle Wasting Using Multi-Omics Approaches., PMID:40207397
Association of cerebrospinal fluid ciliary neurotrophic factor levels with cognitive decline and disease progression., PMID:40179226
Ciliary neurotrophic factor (CNTF) contributes to pelvic organ prolapse by modulating collagen expression via the JAK2-STAT3 pathway., PMID:40082289
Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic activity enhancement., PMID:40038284
Neuroprotective Mechanisms of Ciliary Neurotrophic Factor in Retinal Ganglion Cells: Insights from Microarray Analysis., PMID:40007093
Synergistic effects of memantine and alpha7 nicotinic acetylcholine receptor agonist PHA-543613 to improve memory of aged rats., PMID:39985181
[Progress of researches on acupuncture treatment of spinal cord injury by promoting axonal regeneration]., PMID:39961764
Ciliary neurotrophic factor attenuates myocardial infarction-induced oxidative stress and ferroptosis via PI3K/Akt signaling., PMID:39954087
Nerve growth factor loaded hypotonic eye drops for corneal nerve repair., PMID:39884437
Role of Ciliary Neurotrophic Factor in Angiotensin II-Induced Hypertension., PMID:39851048
Inhibition of Vascular Endothelial Growth Factor Reduces Photoreceptor Death in Retinal Neovascular Disease via Neurotrophic Modulation in Müller Glia., PMID:39789237
Serotonin enhances neurogenesis biomarkers, hippocampal volumes, and cognitive functions in Alzheimer's disease., PMID:39696587
Marcks overexpression in retinal ganglion cells promotes optic nerve regeneration., PMID:39695101
Clickable, Thermally Responsive Hydrogels Enabled by Recombinant Spider Silk Protein and Spy Chemistry for Sustained Neurotrophin Delivery., PMID:39648660
Quantitative assessment of the associations between ABCA1 gene polymorphism and glaucoma risk, evidence from a meta-analysis., PMID:39612451
Indigenous gut microbiota constitutively drive release of ciliary neurotrophic factor from mucosal enteric glia to maintain the homeostasis of enteric neural circuits., PMID:39606241
Effects of a ciliary neurotrophic factor (CNTF) small-molecule peptide mimetic in an in vitro and in vivo model of CDKL5 deficiency disorder., PMID:39592934
Molecular physiology unlocks the mystery that relates cognitive impairment with the retina in schizophrenia and autism spectrum disorders: a perspective review., PMID:39588547
Ciliary neurotrophic factor activation of astrocytes mediates neuronal damage via the IL‑6/IL‑6R pathway., PMID:39575470
Efficacy and Mechanism of Schisandra chinensis Fructus Water Extract in Alzheimer's Disease: Insights from Network Pharmacology and Validation in an Amyloid-β Infused Animal Model., PMID:39519586
Interleukin-11 receptor is an alternative α-receptor for interleukin-6 and the chimeric cytokine IC7., PMID:39473075
Influence of Lactation Stage on Content of Neurotrophic Factors, Leptin, and Insulin in Human Milk., PMID:39459341
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601
Exploring the reduction in aquaporin-4 and increased expression of ciliary neurotrophic factor with the frontal-striatal gliosis induced by chronic high-fat dietary stress., PMID:39374168
Zeaxanthin and Lutein Ameliorate Alzheimer's Disease-like Pathology: Modulation of Insulin Resistance, Neuroinflammation, and Acetylcholinesterase Activity in an Amyloid-β Rat Model., PMID:39337316
Effects of Short-Term Treatment of Rabbit Extraocular Muscle With Ciliary Neurotrophic Factor., PMID:39330989
Optimization of an autaptic culture system for studying cholinergic synapses in sympathetic ganglia., PMID:39325088
Investigating the influence of estrous cycle-dependent hormonal changes on neurogenesis in adult mice., PMID:39305945
A miR-383-5p Signaling Hub Coordinates the Axon Regeneration Response to Inflammation., PMID:39266301
Transgenic silkworm expressing bioactive human ciliary neurotrophic factor for biomedical application., PMID:39219303
Exploring the protective effects of Qiju Granule in a rat model of dry age-related macular degeneration., PMID:39197675
Serum Levels and Clinical Significance of NSE, BDNF and CNTF in Patients with Cancer-associated Ischemic Stroke Complicated with Post-stroke Depression., PMID:39129688
Effects of house-cultivated edible bird's nest on immunoglobulin and cytokine release in vitro., PMID:39077458
Evaluating the IL-6 Family of Cytokines Throughout Equine Gestation., PMID:39072818
LncRNA GAS5 modulates Schwann cell function and enhances facial nerve injury repair via the miR-138-5p/CXCL12 axis., PMID:39068616
Lipid Nanoparticle-Mediated Delivery of mRNA Into the Mouse and Human Retina and Other Ocular Tissues., PMID:38980261
Ciliary neurotrophic factor promotes the development of homocysteine-induced vascular endothelial injury through inflammation mediated by the JAK2/STAT3 signaling pathway., PMID:38848951
Photobiomodulation: a novel approach to promote trans-differentiation of adipose-derived stem cells into neuronal-like cells., PMID:38819070
Acute responses of strength-related gene expressions to maximum strength and force sense acuity., PMID:38812641
GDF15 controls primary cilia morphology and function thereby affecting progenitor proliferation., PMID:38719753
Enhanced therapeutic efficacy for glioblastoma immunotherapy with an oncolytic herpes simplex virus armed with anti-PD-1 antibody and IL-12., PMID:38681801
Iron deficiency in astrocytes alters cellular status and impacts on oligodendrocyte differentiation., PMID:38656648