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Anti-Human GRIN1/NMDAR1 Antibody (A4B2)

Catalog #:   RHG05301 Specific References (27) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: Blocking, ELISA, WB
Accession: Q05586
Overview

Catalog No.

RHG05301

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

N-methyl-D-aspartate receptor subunit NR1, GluN1, Glutamate [NMDA] receptor subunit zeta-1, Glutamate receptor ionotropic, NMDA 1, NMD-R1, GRIN1, NMDAR1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q05586

Applications

Blocking, ELISA, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

A4B2

Data Image
  • Western Blot
    Recombinant Protein were subjected to SDS PAGE followed by western blot with GRIN1/NMDAR1 antibody (RHG05301) at 1μg/ml.

    Lane 1: Recombinant Human GRIN1/NMDAR1 Protein

    Second Ab: Goat Anti-Mouse IgG H&L Polyclonal antibody, HRP (PMB96431) at 0.1 μg/mL.

    Predict MW: 90 kDa
    Observed MW: 90 kDa
References

Bridging the gap: insights into sensorimotor deficits in NMDA receptor antibody encephalitis., PMID:40026244

Molecular scalpels dissect new GluN1 hot spots in anti-NMDA receptor encephalitis., PMID:39752539

NMDAR1 autoantibodies as potential biomarkers for schizophrenia phenotyping., PMID:39300631

NLRP4E regulates actin cap formation through SRC and CDC42 during oocyte meiosis., PMID:38730334

Cellular prion protein in human plasma-derived extracellular vesicles promotes neurite outgrowth via the NMDA receptor-LRP1 receptor system., PMID:35090893

Longitudinal CSF Findings in Autoimmune Encephalitis-A Monocentric Cohort Study., PMID:33828556

Exploratory investigation on antibodies to GluN1 and cognitive dysfunction in patients with chronic autoimmune psychosis., PMID:33359543

Characteristics of internalization of NMDA-type GluRs with antibodies to GluN1 and GluN2B., PMID:33091764

Autoimmune encephalitis., PMID:31808454

An update on anti-NMDA receptor encephalitis for neurologists and psychiatrists: mechanisms and models., PMID:31326280

Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Challenging Diagnosis in the Emergency Department., PMID:31268960

Rapid onset of altered mental status with progressive autonomic instability and hypoventilation in a 2-year-old male., PMID:32134592

Uncoupling the widespread occurrence of anti-NMDAR1 autoantibodies from neuropsychiatric disease in a novel autoimmune model., PMID:29426955

Serum complement levels in anti-N-methyl-d-aspartate receptor encephalitis., PMID:29053906

[Therapy of Antibody-Associated Autoimmune Encephalitis]., PMID:27299787

Ethanol upregulates NMDA receptor subunit gene expression in human embryonic stem cell-derived cortical neurons., PMID:26266540

Semi-quantitative analyses of antibodies to N-methyl-d-aspartate type glutamate receptor subunits (GluN2B & GluN1) in the clinical course of Rasmussen syndrome., PMID:25986190

Absence of N-Methyl-D-Aspartate Receptor IgG Autoantibodies in Schizophrenia: The Importance of Cross-Validation Studies., PMID:25970159

Differential alterations of neocortical GluN receptor subunits in patients with mixed subcortical ischemic vascular dementia and Alzheimer's disease., PMID:25261450

[Autoimmune encephalitis as a cause of psychosis]., PMID:24730197

Pathological reorganization of NMDA receptors subunits and postsynaptic protein PSD-95 distribution in Alzheimer's disease., PMID:24156266

Stroke patients develop antibodies that react with components of N-methyl-D-aspartate receptor subunit 1 in proportion to lesion size., PMID:23723305

Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro., PMID:22486492

Association of GRIN1 and GRIN2A-D with schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk., PMID:21919190

Breast cancer expresses functional NMDA receptors., PMID:19784770

Dynamic expression patterns of G protein-regulated inducer of neurite outgrowth 1 (GRIN1) and its colocalization with Galphao implicate significant roles of Galphao-GRIN1 signaling in nervous system., PMID:18729205

The clinical potential of antiepileptic gene therapy., PMID:15500405

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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For research use only. Not for human or drug use.

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Anti-Human GRIN1/NMDAR1 Antibody (A4B2) [RHG05301]
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