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Anti-Human TIMP2 Antibody (SAA0317)

Catalog #:   RHD14501 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: Blocking, ELISA
Accession: P16035
Overview

Catalog No.

RHD14501

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

TIMP2, TIMP-2, CSC-21K, Tissue inhibitor of metalloproteinases 2, Metalloproteinase inhibitor 2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P16035

Applications

Blocking, ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0317

Data Image
References

TIMP-2 Modulates 5-Fu Resistance in Colorectal Cancer Through Regulating JAK-STAT Signalling Pathway., PMID:40118773

Expression of MMP-2, MMP-9 and TIMP-2 in pituitary tumors and their relationship with cavernous sinus invasion., PMID:39810846

Perfluoroalkyl substances (PFAS) exposure and preeclampsia risk: Impaired angiogenesis through suppression of VEGF signaling., PMID:39732411

Differential Inflammatory Cytokine Elaboration in Serum from Brick Kiln Workers in Bhaktapur, Nepal., PMID:38920561

The Role of Matrix Metalloproteinases in Thoracic Aortic Disease: Are They Indicators for the Pathogenesis of Dissections?, PMID:38540232

CETP-derived Peptide Seq-1, the Key Component of HB-ATV-8 Vaccine Prevents Stress Responses, and Promotes Downregulation of Pro-Fibrotic Genes in Hepatocytes and Stellate Cells., PMID:38301446

IgE Immune Complexes Mitigate Eosinophilic Immune Responses through NLRC4 Inflammasome., PMID:37885469

Cytokine status and significant increase of IL-6 and sIL-6R in the aqueous humor of diabetic cataract patients revealed by quantitative multiplexed assays., PMID:37694725

MT1-MMP as a Key Regulator of Metastasis., PMID:37681919

Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody., PMID:37674627

Substrate mechanical properties bias MSC paracrine activity and therapeutic potential., PMID:37422008

PhosY-secretome profiling combined with kinase-substrate interaction screening defines active c-Src-driven extracellular signaling., PMID:37243593

Skeletonema marinoi Extracts and Associated Carotenoid Fucoxanthin Downregulate Pro-Angiogenic Mediators on Prostate Cancer and Endothelial Cells., PMID:37048126

Role of Matrix Metalloproteinases and Their Inhibitors in Locally Invasive Papillary Thyroid Cancer., PMID:36551933

Among biomarkers of neutrophil activity, matrix metalloproteinases 8 independently predicts remission of metabolic syndrome., PMID:36411219

Metalloproteinases and Tissue Inhibitors in Generalized Myasthenia Gravis. A Preliminary Study., PMID:36358365

Recreational physical activity before and during pregnancy and placental DNA methylation-an epigenome-wide association study., PMID:35771992

The role of tissue inhibitor of metalloproteinases in the aetiology of inguinal and incisional hernias., PMID:35274445

Inhibitory effect of membrane‑free stem cell components derived from adipose tissues on skin inflammation in keratinocytes., PMID:35169867

Low-Molecular-Weight Heparin Enhanced Therapeutic Effects of Human Adipose-Derived Stem Cell Administration in a Mouse Model of Lupus Nephritis., PMID:35095868

The effect of short-term intensive insulin therapy on inflammatory cytokines in patients with newly diagnosed type 2 diabetes., PMID:35040554

TIMP-2 regulates 5-Fu resistance via the ERK/MAPK signaling pathway in colorectal cancer., PMID:35022331

Identification of Angiogenic Cargo in Extracellular Vesicles Secreted from Human Adipose Tissue-Derived Stem Cells and Induction of Angiogenesis In Vitro and In Vivo., PMID:33916460

Prostaglandin F2α agonists induced enhancement in collagen1 expression is involved in the pathogenesis of the deepening of upper eyelid sulcus., PMID:33903711

Granulocyte-macrophage colony-stimulating factor initiates amniotic membrane rupture and preterm birth in a mouse model., PMID:33772943

Transforming growth factor-β1 inhibits interleukin-1β-induced expression of inflammatory genes and Cathepsin S activity in human vascular smooth muscle cells., PMID:33683760

Response to trastuzumab and investigation of expression profiles of matrix metalloproteinase-related proteins in primary breast cancer stem cells., PMID:33471244

Proteomic Analysis and Cell Viability of Nine Amnion, Chorion, Umbilical Cord, and Amniotic Fluid-Derived Products., PMID:33356465

Cerebrospinal fluid cytokines and metalloproteinases in cerebral amyloid angiopathy-related inflammation., PMID:33247941

Tissue Inhibitor of Metalloproteinases-2 Mediates Kidney Injury during Sepsis., PMID:33091916

A human retinal microvascular endothelial-pericyte co-culture model to study diabetic retinopathy in vitro., PMID:33039459

Cancer-associated fibroblasts promote the migration and invasion of gastric cancer cells via activating IL-17a/JAK2/STAT3 signaling., PMID:32793721

Effect of natalizumab treatment on metalloproteinases and their inhibitors in a mouse model of multiple sclerosis., PMID:32776909

Inhibitory Effect of Tetramerized Single-Chain Variable Fragment of Anti-Cyclic Citrullinated Peptide Antibodies on the Proliferation, Activation, and Secretion of Cytokines of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis In Vitro Co-Culture System., PMID:32737657

CaSR Antagonist (Calcilytic) NPS 2143 Hinders the Release of Neuroinflammatory IL-6, Soluble ICAM-1, RANTES, and MCP-2 from Aβ-Exposed Human Cortical Astrocytes., PMID:32498476

Hedgehog signaling promotes angiogenesis directly and indirectly in pancreatic cancer., PMID:32444947

Expression of Matrix Metalloproteinases and Their Inhibitors in Endometrium: High Levels in Endometriotic Lesions., PMID:32325785

Inhibitory Effects of a Reengineered Anthrax Toxin on Canine Oral Mucosal Melanomas., PMID:32121654

Role of matrix metalloproteinases and their inhibitors in the development of cervical metastases in papillary thyroid cancer., PMID:31646745

Extensive serum biomarker analysis in patients with non-small-cell lung carcinoma., PMID:31629110

Carbon Nanomaterials Stimulate HMGB1 Release From Macrophages and Induce Cell Migration and Invasion., PMID:31504961

Characteristics of Changes in Inflammatory Cytokines as a Function of Hepatic Ischemia-Reperfusion Injury Stage in Mice., PMID:31494794

Localization of the ultraviolet-sensor Opn5m and its effect on myopia-related gene expression in the late-embryonic chick eye., PMID:31463372

Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis., PMID:31412254

Proteomic analysis of the secretome of adipose tissue-derived murine mesenchymal cells overexpressing telomerase and myocardin., PMID:31055035

Bone-derived Nestin-positive mesenchymal stem cells improve cardiac function via recruiting cardiac endothelial cells after myocardial infarction., PMID:31029167

Enhanced Anti-Cancer Effects of Conditioned Medium from Hypoxic Human Umbilical Cord-Derived Mesenchymal Stem Cells., PMID:31023003

Evaluation of Local Injection of Bevacizumab against Triple-Negative Breast Cancer Xenograft Tumors., PMID:30848190

Matrix Metalloproteinases and Their Tissue Inhibitors: an Evaluation of Novel Biomarkers in ANCA-Associated Vasculitis., PMID:32362306

Induction of human aortic myofibroblast-mediated extracellular matrix dysregulation: A potential mechanism of fluoroquinolone-associated aortopathy., PMID:30528439

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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Anti-Human TIMP2 Antibody (SAA0317) [RHD14501]
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