Catalog No.
PHB89901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human C3c (Glu1322-Cys1661).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
C3, ASP, Complement C3, C3adesArg, C3bc, CPAMD1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
Purification
Purified by antigen affinity column.
Accession
P01024
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Production and Functional Verification of 8-Gene (GGTA1, CMAH, β4GalNT2, hCD46, hCD55, hCD59, hTBM, hCD39)-Edited Donor Pigs for Xenotransplantation., PMID:40190036
Glomerular mesangial cells derived complement factor H regulates complement activation, influences cell proliferation, and maintains actin cytoskeleton., PMID:40157080
Claudin-2 enhances human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells by modulating antibody binding and complement activation., PMID:40040710
Autoimmune screening panel in patients with multiple sclerosis: A Vienna multiple sclerosis database study., PMID:39601436
Bone impairment in atypical hemolytic and uremic syndrome treated by long-term eculizumab., PMID:39422762
Serotype 15C Streptococcus pneumoniae resistant to classical complement deposition and agglutination by polyclonal rabbit anti-capsular 15B sera., PMID:39368131
Immunofluorescence findings in a reactivating lichenoid photoallergic chronic dermatitis (actinic reticuloid)., PMID:39145412
C3 concentrations can be normal in patients with C3 glomerulopathy secondary to C3 nephritic factor., PMID:38538072
Lower serum AMH concentration is correlated with serum IgG1 decreased in the infertile woman: A real-world retrospective study., PMID:38286181
Insights into the immunological description of cryoglobulins with regard to detection and characterization in Slovenian rheumatological patients., PMID:37993756
Thrombotic microangiopathy in a patient with anti-signal recognition particle antibody-positive immune-mediated necrotizing myopathy., PMID:37828793
Characteristics of Complement Protein Deposition in Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposition., PMID:37713183
Case report: A case of epidermolysis bullosa acquisita with IgG and IgM anti-basement membrane zone antibodies relapsed after COVID-19 mRNA vaccination., PMID:37324140
Treatment of thrombocytopenia and thrombosis in HIT in mice using deglycosylated KKO: a novel therapeutic?, PMID:37196641
[Glomerulopathy in kidney neoplasms: frequency of occurrence, structure of morbidity]., PMID:37053349
Dysregulated biomarkers of innate and adaptive immunity predict infections and disease progression in cirrhosis., PMID:37035457
Magnetic blood purification-based soluble fms-like tyrosine kinase-1 removal in comparison with dextran sulfate apheresis and therapeutic plasma exchange., PMID:36995348
Successful pharmacological intervention at different levels of the complement system in an in vitro complement fixation model for bullous pemphigoid., PMID:36704908
Cyclosporine therapy could be considered for membranoproliferative glomerulonephritis with immunoglobulin A deposits: a case report., PMID:36344919
Tacrolimus Induction Therapy for Nephrotic Syndrome Caused by Minimal Mesangial Lupus Nephritis with Lupus Podocytopathy: A Case-Based Review., PMID:36336892
Role of light and immunofluorescence microscopy to differentiate primary and secondary membranous nephropathy., PMID:36308187
Complement activation in Hidradenitis suppurativa: Covert low-grade inflammation or innocent bystander?, PMID:36211440
α-2,6-sialic acid/IgG anti-dsDNA ratios correlate with human lupus disease activity and possible mechanisms: A pilot study., PMID:35531921
Cutaneous Vesiculobullous Lesions: A Clinicopathologic Study., PMID:35435824
Low Serum Levels of Complement C3c at Diagnosis Indicate Poor Outcome in Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis., PMID:35257082
Novel approaches beyond standard immunofluorescence for kidney biopsies., PMID:35256574
Lectin and alternative complement pathway activation in cutaneous manifestations of IgA-vasculitis: A new target for therapy?, PMID:35121432
Yi Shen An, a Chinese traditional prescription, ameliorates membranous glomerulonephritis induced by cationic bovine serum albumin in rats., PMID:35001799
Glomerulonephritis Associated with Infective Endocarditis Showing Serological Positivity for PR3-anti-neutrophil Cytoplasmic Antibody and Anti-glomerular Basement Membrane Antibody., PMID:34980793
Proteinuria is accompanied by intratubular complement activation and apical membrane deposition of C3dg and C5b-9 in kidney transplant recipients., PMID:34927448
Immunization with desmoglein 3 induces non-pathogenic autoantibodies in mice., PMID:34731225
Characteristics of immune and inflammatory responses among different age groups of pediatric patients with COVID-19 in China., PMID:34341947
The Spectrum of C4d Deposition in Renal Biopsies of Lupus Nephritis Patients., PMID:34276649
Systematic Scoring of Tubular Injury Patterns Reveals Interplay between Distinct Tubular and Glomerular Lesions in ANCA-Associated Glomerulonephritis., PMID:34207078
Complement Components C3 and C4 Indicate Vasculitis Manifestations to Distinct Renal Compartments in ANCA-Associated Glomerulonephritis., PMID:34205415
Complement mediates binding and procoagulant effects of ultralarge HIT immune complexes., PMID:34189574
Alternative Complement Pathway Is Activated and Associated with Galactose-Deficient IgA1 Antibody in IgA Nephropathy Patients., PMID:34177889
A new biflavonoids from Aster tataricus induced non-apoptotic cell death in A549 cells., PMID:33615932
HLA class I depletion by citric acid, and irradiation of apheresis platelets for transfusion of refractory patients., PMID:33580979
A Case of Systemic Lupus Erythematosus and Antineutrophil Cytoplasmic Antibodies-Associated Vasculitis Overlap Syndrome., PMID:33505756
Effects of Hericium erinaceus polysaccharide on immunity and apoptosis of the main immune organs in Muscovy duck reovirus-infected ducklings., PMID:33421472
Diagnostic Utility of C4d by Direct Immunofluorescence in Bullous Pemphigoid., PMID:33395046
Malignancy-associated membranous nephropathy with PLA2R double-positive for glomeruli and carcinoma., PMID:33393071
The development of rapidly progressive glomerulonephritis associated with both antineutrophil cytoplasmic antibody-associated vasculitis and anti-glomerular basement membrane nephritis in the course of nontuberculous mycobacterium infection: a case report., PMID:33308324
Ex vivo assays to detect complement activation in complementopathies., PMID:33148511
Association of Glomerular Complement C4c Deposition With the Progression of Diabetic Kidney Disease in Patients With Type 2 Diabetes., PMID:32983156
A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity., PMID:32938727
Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition., PMID:32877502
Pediatric lupus nephritis - An evil cousin of its adult counterpart: A single-center based experience from a tertiary care hospital of Eastern India., PMID:32769328
Atrase B, a novel metalloprotease with anti-complement and anti-coagulant activity, significantly delays discordant cardiac xenograft rejection., PMID:32529740
For research use only. Not for human or drug use.
