Catalog No.
DHB91604
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG1
Clonality
Monoclonal
Target
Transforming growth factor beta-1 proprotein, LAP, TGF-beta-1, TGFB1, TGFB, Glioblastoma-derived T-cell suppressor factor, TGF-beta-2, LAP, G-TSF, TGFB2, Cetermin, Transforming growth factor beta-2 proprotein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P01137 & P61812
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
XOMA 089
Defective neutrophil clearance in JAK2V617F myeloproliferative neoplasms drives myelofibrosis via immune checkpoint CD24., PMID:40373279
Relation of Cytokine Profile and Antibody Values to Post-Translational Protein Modifications in Patients with Rheumatoid Arthritis (Preliminary Data)., PMID:40353964
Suppression of renal crystal formation, inflammation, and fibrosis by blocking oncostatin M receptor β signaling., PMID:39572752
NOTCH1 drives tumor plasticity and metastasis in hepatocellular carcinoma., PMID:39484457
Losartan alters osteoblast differentiation and increases bone mass through inhibition of TGFB signalling in vitro and in an OIM mouse model., PMID:39185375
Obesity Enhances Non-Th2 Airway Inflammation in a Murine Model of Allergic Asthma., PMID:38892358
Medical Management for Fracture Prevention in Children with Osteogenesis Imperfecta., PMID:38553634
CD44 expression on murine hepatic stellate cells promotes the induction of monocytic and polymorphonuclear myeloid-derived suppressor cells., PMID:38484149
A State-of-the-Art Review on the Recent Advances of Mesenchymal Stem Cell Therapeutic Application in Systematic Lupus Erythematosus., PMID:38031988
Radial glia promote microglial development through integrin αVβ8 -TGFβ1 signaling., PMID:37790363
ASCL2 induces an immune excluded microenvironment by activating cancer-associated fibroblasts in microsatellite stable colorectal cancer., PMID:37591954
Transforming Growth Factor-β Blockade in Pancreatic Cancer Enhances Sensitivity to Combination Chemotherapy., PMID:37263309
Breast milk microRNAs: Potential players in oral tolerance development., PMID:36999032
Nasal administration of anti-CD3 monoclonal antibody modulates effector CD8+ T cell function and induces a regulatory response in T cells in human subjects., PMID:36505477
[Morphogenetic and pathogenetic features of hypertrophic and keloid scars of the head and neck]., PMID:36469714
IL-1 receptor antagonist (IL-1RA) suppresses a hyper-IL-17 response-mediated bone loss in a murine experimental periodontitis., PMID:36191445
Evaluation of effective factors on IL-10 signaling in B cells in patients with selective IgA deficiency., PMID:36102856
Tumor-derived CTF1 (cardiotrophin 1) is a critical mediator of stroma-assisted and autophagy-dependent breast cancer cell migration, invasion and metastasis., PMID:35722965
Special issue "The advance of solid tumor research in China": Multi-omics analysis based on 1311 clear cell renal cell carcinoma samples identifies a glycolysis signature associated with prognosis and treatment response., PMID:35579992
The level of transforming growth factor-β as a possible predictor of cyclophosphamide response in children with steroid-resistant nephrotic syndrome., PMID:35223413
Utilization of Treg Cells in Solid Organ Transplantation., PMID:35185868
Progressive Retinal and Optic Nerve Damage in a Mouse Model of Spontaneous Opticospinal Encephalomyelitis., PMID:35140707
Transcript levels of cytokine coding genes in peripheral blood and tissues of patients with periodontitis., PMID:34864655
TGF-beta pathway inhibition as the therapeutic acceleration of diabetic bone regeneration., PMID:34775640
Chronic consumption of sweeteners in mice and its effect on the immune system and the small intestine microbiota., PMID:34559497
Dual PD-L1 and TGF-b blockade in patients with recurrent respiratory papillomatosis., PMID:34462327
Exposure to p40 in Early Life Prevents Intestinal Inflammation in Adulthood Through Inducing a Long-Lasting Epigenetic Imprint on TGFβ., PMID:33482393
Macrophage to myofibroblast transition contributes to subretinal fibrosis secondary to neovascular age-related macular degeneration., PMID:33239022
Analyzing Signaling Pathways Using Antibody Arrays., PMID:33237422
Bone morphogenetic protein 7 promotes resistance to immunotherapy., PMID:32973129
Dietary Soy Protein Isolate Attenuates Intestinal Immunoglobulin and Mucin Expression in Young Mice Compared with Casein., PMID:32911830
Impact of fascioliasis reinfection on Fasciola hepatica egg shedding: relationship with the immune-regulatory response., PMID:32371223
No Major Effect of Innate Immune Genetics on Acute Kidney Rejection in the First 2 Weeks Post-Transplantation., PMID:32153387
The relation between anti-TGBFR1 immunohistochemical reaction and low Ki67, small tumor size and high estrogen receptor expression in invasive breast cancer., PMID:32103597
Characterization and bioactivity of grass carp (Ctenopharyngodon idella) interleukin-21: Inducible production and involvement in inflammatory regulation., PMID:32014588
Endothelial autophagy deficiency induces IL6 - dependent endothelial mesenchymal transition and organ fibrosis., PMID:31965901
Bronchoalveolar lavage fluid cytokine, cytology and IgE allergen in horses with equine asthma., PMID:31786444
Inhibition of the stem cell factor 248 isoform attenuates the development of pulmonary remodeling disease., PMID:31747308
Fibrosis Mediators in the Colonic Mucosa of Acute and Healed Ulcerative Colitis., PMID:31584460
Long-term Kinetics of Intragraft Gene Signatures in Renal Allograft Tolerance Induced by Transient Mixed Chimerism., PMID:31397805
GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS., PMID:31152154
Intragraft vasculitis and gene expression analysis: Association with acute rejection and prediction of mortality in long-term heart transplantation., PMID:30080295
IL-10 Receptor or TGF-β Neutralization Abrogates the Protective Effect of a Specific Nondigestible Oligosaccharide Mixture in Cow-Milk-Allergic Mice., PMID:29986071
Trastuzumab inhibits pituitary tumor cell growth modulating the TGFB/SMAD2/3 pathway., PMID:29875136
RANKL Triggers Treg-Mediated Immunoregulation in Inflammatory Osteolysis., PMID:29499125
[Significance of Immune-Cell Infiltration in Gastric]., PMID:29483408
Disruption of postnatal folliculogenesis and development of ovarian tumor in a mouse model with aberrant transforming growth factor beta signaling., PMID:29221447
Anti-CD47 monoclonal antibody therapy reduces ischemia-reperfusion injury of renal allografts in a porcine model of donation after cardiac death., PMID:29087049
Healing and mucosal immunity in the skin of experimentally wounded gilthead seabream (Sparus aurata L)., PMID:29017945
MDM2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells., PMID:28817834