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Research Grade Anti-Human TGFB Antibody (XOMA 089)

Catalog #:   DHB91604 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG1
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHB91604

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG1

Clonality

Monoclonal

Target

Transforming growth factor beta-1 proprotein, LAP, TGF-beta-1, TGFB1, TGFB, Glioblastoma-derived T-cell suppressor factor, TGF-beta-2, LAP, G-TSF, TGFB2, Cetermin, Transforming growth factor beta-2 proprotein

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01137 & P61812

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

XOMA 089

Data Image
References

Defective neutrophil clearance in JAK2V617F myeloproliferative neoplasms drives myelofibrosis via immune checkpoint CD24., PMID:40373279

Relation of Cytokine Profile and Antibody Values to Post-Translational Protein Modifications in Patients with Rheumatoid Arthritis (Preliminary Data)., PMID:40353964

Suppression of renal crystal formation, inflammation, and fibrosis by blocking oncostatin M receptor β signaling., PMID:39572752

NOTCH1 drives tumor plasticity and metastasis in hepatocellular carcinoma., PMID:39484457

Losartan alters osteoblast differentiation and increases bone mass through inhibition of TGFB signalling in vitro and in an OIM mouse model., PMID:39185375

Obesity Enhances Non-Th2 Airway Inflammation in a Murine Model of Allergic Asthma., PMID:38892358

Medical Management for Fracture Prevention in Children with Osteogenesis Imperfecta., PMID:38553634

CD44 expression on murine hepatic stellate cells promotes the induction of monocytic and polymorphonuclear myeloid-derived suppressor cells., PMID:38484149

A State-of-the-Art Review on the Recent Advances of Mesenchymal Stem Cell Therapeutic Application in Systematic Lupus Erythematosus., PMID:38031988

Radial glia promote microglial development through integrin αVβ8 -TGFβ1 signaling., PMID:37790363

ASCL2 induces an immune excluded microenvironment by activating cancer-associated fibroblasts in microsatellite stable colorectal cancer., PMID:37591954

Transforming Growth Factor-β Blockade in Pancreatic Cancer Enhances Sensitivity to Combination Chemotherapy., PMID:37263309

Breast milk microRNAs: Potential players in oral tolerance development., PMID:36999032

Nasal administration of anti-CD3 monoclonal antibody modulates effector CD8+ T cell function and induces a regulatory response in T cells in human subjects., PMID:36505477

[Morphogenetic and pathogenetic features of hypertrophic and keloid scars of the head and neck]., PMID:36469714

IL-1 receptor antagonist (IL-1RA) suppresses a hyper-IL-17 response-mediated bone loss in a murine experimental periodontitis., PMID:36191445

Evaluation of effective factors on IL-10 signaling in B cells in patients with selective IgA deficiency., PMID:36102856

Tumor-derived CTF1 (cardiotrophin 1) is a critical mediator of stroma-assisted and autophagy-dependent breast cancer cell migration, invasion and metastasis., PMID:35722965

Special issue "The advance of solid tumor research in China": Multi-omics analysis based on 1311 clear cell renal cell carcinoma samples identifies a glycolysis signature associated with prognosis and treatment response., PMID:35579992

The level of transforming growth factor-β as a possible predictor of cyclophosphamide response in children with steroid-resistant nephrotic syndrome., PMID:35223413

Utilization of Treg Cells in Solid Organ Transplantation., PMID:35185868

Progressive Retinal and Optic Nerve Damage in a Mouse Model of Spontaneous Opticospinal Encephalomyelitis., PMID:35140707

Transcript levels of cytokine coding genes in peripheral blood and tissues of patients with periodontitis., PMID:34864655

TGF-beta pathway inhibition as the therapeutic acceleration of diabetic bone regeneration., PMID:34775640

Chronic consumption of sweeteners in mice and its effect on the immune system and the small intestine microbiota., PMID:34559497

Dual PD-L1 and TGF-b blockade in patients with recurrent respiratory papillomatosis., PMID:34462327

Exposure to p40 in Early Life Prevents Intestinal Inflammation in Adulthood Through Inducing a Long-Lasting Epigenetic Imprint on TGFβ., PMID:33482393

Macrophage to myofibroblast transition contributes to subretinal fibrosis secondary to neovascular age-related macular degeneration., PMID:33239022

Analyzing Signaling Pathways Using Antibody Arrays., PMID:33237422

Bone morphogenetic protein 7 promotes resistance to immunotherapy., PMID:32973129

Dietary Soy Protein Isolate Attenuates Intestinal Immunoglobulin and Mucin Expression in Young Mice Compared with Casein., PMID:32911830

Impact of fascioliasis reinfection on Fasciola hepatica egg shedding: relationship with the immune-regulatory response., PMID:32371223

No Major Effect of Innate Immune Genetics on Acute Kidney Rejection in the First 2 Weeks Post-Transplantation., PMID:32153387

The relation between anti-TGBFR1 immunohistochemical reaction and low Ki67, small tumor size and high estrogen receptor expression in invasive breast cancer., PMID:32103597

Characterization and bioactivity of grass carp (Ctenopharyngodon idella) interleukin-21: Inducible production and involvement in inflammatory regulation., PMID:32014588

Endothelial autophagy deficiency induces IL6 - dependent endothelial mesenchymal transition and organ fibrosis., PMID:31965901

Bronchoalveolar lavage fluid cytokine, cytology and IgE allergen in horses with equine asthma., PMID:31786444

Inhibition of the stem cell factor 248 isoform attenuates the development of pulmonary remodeling disease., PMID:31747308

Fibrosis Mediators in the Colonic Mucosa of Acute and Healed Ulcerative Colitis., PMID:31584460

Long-term Kinetics of Intragraft Gene Signatures in Renal Allograft Tolerance Induced by Transient Mixed Chimerism., PMID:31397805

GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS., PMID:31152154

Intragraft vasculitis and gene expression analysis: Association with acute rejection and prediction of mortality in long-term heart transplantation., PMID:30080295

IL-10 Receptor or TGF-β Neutralization Abrogates the Protective Effect of a Specific Nondigestible Oligosaccharide Mixture in Cow-Milk-Allergic Mice., PMID:29986071

Trastuzumab inhibits pituitary tumor cell growth modulating the TGFB/SMAD2/3 pathway., PMID:29875136

RANKL Triggers Treg-Mediated Immunoregulation in Inflammatory Osteolysis., PMID:29499125

[Significance of Immune-Cell Infiltration in Gastric]., PMID:29483408

Disruption of postnatal folliculogenesis and development of ovarian tumor in a mouse model with aberrant transforming growth factor beta signaling., PMID:29221447

Anti-CD47 monoclonal antibody therapy reduces ischemia-reperfusion injury of renal allografts in a porcine model of donation after cardiac death., PMID:29087049

Healing and mucosal immunity in the skin of experimentally wounded gilthead seabream (Sparus aurata L)., PMID:29017945

MDM2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells., PMID:28817834

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Research Grade Anti-Human TGFB Antibody (XOMA 089) [DHB91604]
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