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Anti-Human Transthyretin amyloidosis Antibody (5A1)

Catalog #:   RHK25504 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2b, kappa
Applications: ELISA, Neutralization, SPR, WB
Overview

Catalog No.

RHK25504

Species reactivity

Human

Host species

Mouse

Isotype

IgG2b, kappa

Clonality

Monoclonal

Target

Transthyretin, Prealbumin, TBPA, TTR, PALB, ATTR, Transthyretin amyloidosis, mis-TTR

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

ELISA, Neutralization, SPR, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

5A1

Data Image
References

Current and emerging treatment options for transthyretin amyloid cardiomyopathy., PMID:40425273

Current Landscape of Therapies for Transthyretin Amyloid Cardiomyopathy., PMID:40335224

A scientometric study on research characteristics and trends of amyloidosis involving the oral cavity., PMID:40224046

Diagnosis of hereditary transthyretin amyloidosis in patients with suspected chronic inflammatory demyelinating polyneuropathy unresponsive to intravenous immunoglobulins: results of a retrospective study., PMID:40025610

Transthyretin Cardiac Amyloidosis: Current and Emerging Therapies., PMID:39841315

New therapies to treat cardiac amyloidosis., PMID:39819772

Advancing treatments for transthyretin amyloid cardiomyopathy: Innovations in RNA silencing, gene editing, TTR stabilization, and degradation., PMID:39775625

Disease-modifying therapies for amyloid transthyretin cardiomyopathy: Current and emerging medications., PMID:39714070

Pathogenesis, manifestations, diagnosis, and management of CNS complications in hereditary ATTR amyloidosis., PMID:39627935

Transthyretin Cardiac Amyloidosis in Australia and New Zealand-A Multi-Site Snapshot for 2022., PMID:39592278

Optimizing drug therapies in cardiac amyloidosis., PMID:39586360

PRX004 in variant amyloid transthyretin (ATTRv) amyloidosis: results of a phase 1, open-label, dose-escalation study., PMID:39472768

Prediction of Cardiac ATTR Depletion by NI006 (ALXN2220) Using Mechanistic PK/PD Modeling., PMID:39410666

Hereditary Transthyretin Amyloidosis Polyneuropathy., PMID:39406377

Structural Basis for Monoclonal Antibody Therapy for Transthyretin Amyloidosis., PMID:39338387

Anti-PEG antibodies associated with reduced therapeutic effect of patisiran in patients with hereditary transthyretin amyloidosis., PMID:39126640

[Clinical case of generalized amyloidosis (ATTR-amyloidosis) with a progressive course of chronic heart failure. Case report]., PMID:39106513

Recent advances in the diagnostic methods and therapeutic strategies of transthyretin cardiac amyloidosis., PMID:39086890

Antithrombotic properties of Tafamidis: An additional protective effect for transthyretin amyloid cardiomyopathy patients., PMID:39029855

Amyloid Neuropathy: From Pathophysiology to Treatment in Light-Chain Amyloidosis and Hereditary Transthyretin Amyloidosis., PMID:38923548

Specific Therapy in Transthyretin Amyloid Cardiomyopathy: Future Perspectives Beyond Tafamidis., PMID:38844305

Identification of isoaspartate-modified transthyretin as potential target for selective immunotherapy of transthyretin amyloidosis., PMID:38801321

Treatment of transthyretin cardiac amyloidosis., PMID:38652263

[Modern Perspectives on Peripheral Neuropathology]., PMID:38589281

Detection of TTR Amyloid in the Conjunctiva Using a Novel Fluorescent Ocular Tracer., PMID:38359019

Breakthrough advances enhancing care in ATTR amyloid cardiomyopathy., PMID:38184468

Epidemiological study of the subtype frequency of systemic amyloidosis listed in the Annual of the Pathological Autopsy Cases in Japan., PMID:38088470

Strong positive light chain immunostaining in a patient with transthyretin amyloidosis., PMID:37551718

RNAi therapeutics for diseases involving protein aggregation: fazirsiran for alpha-1 antitrypsin deficiency-associated liver disease., PMID:37470509

Phase 1 Trial of Antibody NI006 for Depletion of Cardiac Transthyretin Amyloid., PMID:37212440

Treatment of amyloidosis: present and future., PMID:37091663

Monoclonal antibodies and amyloid removal as a therapeutic strategy for cardiac amyloidosis., PMID:37091656

Statin-Induced Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (Anti-HMGCR) Myopathy., PMID:36843759

Monoclonal Gammopathy of Undetermined Significance in Patients With Transthyretin Amyloidosis (ATTR): Analysis Using the iStopMM Criteria., PMID:36621346

Antisense Oligonucleotide Therapy for the Nervous System: From Bench to Bedside with Emphasis on Pediatric Neurology., PMID:36365206

Early transverse tubule involvement in cardiomyocytes in hereditary transthyretin amyloidosis: a possible cause of cardiac events., PMID:35872346

Clinical advances of RNA therapeutics for treatment of neurological and neuromuscular diseases., PMID:35482908

Cardiac Amyloidosis Treatment., PMID:35414852

Enhanced quantitative method for the diagnosis of grade 1 cardiac amyloidosis in 99mTc-DPD scintigraphy., PMID:35110594

Developing Therapy for Transthyretin Amyloidosis., PMID:35077703

Yet another amyloidosis., PMID:34965957

Pathological review of cardiac amyloidosis using autopsy cases in a single Japanese institution., PMID:34653913

The Ultrastructure of Tissue Damage by Amyloid Fibrils., PMID:34361762

Progress and challenges in the treatment of cardiac amyloidosis: a review of the literature., PMID:34089308

Potential Cardiac Amyloid PET/CT Imaging Targets for Differentiating Immunoglobulin Light Chain From Transthyretin Amyloidosis., PMID:34081210

A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells., PMID:34035264

Pathophysiology and Therapeutic Approaches to Cardiac Amyloidosis., PMID:33983835

Transthyretin Amyloid Cardiomyopathy-Current and Future Therapies., PMID:33685242

A case of wild-type transthyretin cardiac amyloidosis with rheumatoid arthritis., PMID:33314981

Understanding and recognizing cardiac amyloidosis., PMID:32941304

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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Anti-Human Transthyretin amyloidosis Antibody (5A1) [RHK25504]
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