Catalog No.
PHA20201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SOCS2 (Met1-Val198).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CIS-2,STAT-induced STAT inhibitor 2,SSI-2,SOCS2,STATI2,CIS2,Cytokine-inducible SH2 protein 2,SSI2,Suppressor of cytokine signaling 2,SOCS-2
Purification
Purified by antigen affinity column.
Accession
O14508
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Effect of DNA methylation on inhibitor development in people with hemophilia A treated with FVIII concentrates., PMID:40502981
Resolution of acute inflammation induced by monosodium urate crystals (MSU) through neutrophil extracellular trap-MSU aggregate-mediated negative signaling., PMID:39605016
Aberrant expression of suppressor of cytokine signaling (SOCS) molecules contributes to the development of allergic diseases., PMID:37641429
LncRNA WDFY3-AS2 suppresses proliferation and invasion in oesophageal squamous cell carcinoma by regulating miR-2355-5p/SOCS2 axis., PMID:32536038
Suppressor of cytokine signaling genes in renal transplant receivers: Association with transplant fate., PMID:31398463
The influence of ustekinumab on expression of STAT1, STAT3, STAT4, SOCS2, and IL17 in patients with psoriasis and in a control., PMID:31330078
Genome-wide association study suggests four variants influencing outcomes with ranibizumab therapy in exudative age-related macular degeneration., PMID:30054556
Natural killer cells and anti-tumor immunity., PMID:29233542
Vitamin D Promotes Pneumococcal Killing and Modulates Inflammatory Responses in Primary Human Neutrophils., PMID:28241127
Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor., PMID:27158906
Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells., PMID:25894659
LPS regulates SOCS2 transcription in a type I interferon dependent autocrine-paracrine loop., PMID:22291912
Nuclear beta-catenin and CD44 upregulation characterize invasive cell populations in non-aggressive MCF-7 breast cancer cells., PMID:20696077
SOCS2 influences LPS induced human monocyte-derived dendritic cell maturation., PMID:19779605
Differences in transcriptomic profile and IgA repertoire between jejunal and ileal Peyer's patches., PMID:19747939
CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance., PMID:19356715
Specific isolation of placenta-derived exosomes from the circulation of pregnant women and their immunoregulatory consequences., PMID:17076679
Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis., PMID:16772372
Suppressor of cytokine signalling 2 (SOCS-2) expression in breast carcinoma., PMID:16189149
Erythropoietin up-regulates SOCS2 in neuronal progenitor cells derived from SVZ of adult rat., PMID:15167538
Suppressors of cytokine signaling regulate Fc receptor signaling and cell activation during immune renal injury., PMID:15153517
A proinflammatory cytokine response is present in the fetal placental vasculature in placental insufficiency., PMID:14634584
Effects of prolactin on cloned human T-lymphocytes., PMID:12668883
For research use only. Not for human or drug use.
