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Anti-Human CCL20/MIP-3-alpha Antibody (SAA0277)

Catalog #:   RHF69601 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: Blocking, ELISA, FCM
Accession: P78556
Overview

Catalog No.

RHF69601

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

Beta-chemokine exodus-1, SCYA20, LARC, C-C motif chemokine 20, Liver and activation-regulated chemokine, Small-inducible cytokine A20, MIP-3-alpha, CCL20, MIP3A, Macrophage inflammatory protein 3 alpha, CC chemokine LARC

Concentration

1.71 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P78556

Applications

Blocking, ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0277

Data Image
  • Flow-cytometry
    Flow-cytometry using anti-human CCL20 antibody.Human peripheral blood lymphocytes were stained with an irrelevant antibody (Blue Histogram) or an anti-human CCL20 antibody monoclonal antibody (Catalog # RHF69601 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # PMB96441) and cells analysed on a NovoCyte Flow Cytometer.
References

Therapeutic Intervention of an Intranasally Administered Monoclonal Antibody Targeting the SARS-CoV-2 Omicron Spike Protein Against SARS-CoV-2 Omicron Infection in Mice., PMID:40465408

Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal adenocarcinoma., PMID:40374617

Validation of an Automated Cell Counter Method for HLA-DR and CD3 Expression in Cells Obtained from Low Volume Human Tears., PMID:40361942

CCL20-CCR6 signaling in tumor microenvironment: Functional roles, mechanisms, and immunotherapy targeting., PMID:40348067

Correlation among ocular surface changes and systemic hematologic indexes and disease activity in primary Sjögren's syndrome: a cross-sectional study., PMID:40329232

Novel Vaccines Targeting the Highly Conserved SARS-CoV-2 ORF3a Ectodomain Elicit Immunogenicity in Mouse Models., PMID:40266087

Persistence of dysfunctional immune response 12 months after SARS-CoV-2 infection and their relationship with pulmonary sequelae and long COVID., PMID:40247373

Enhanced mucosal immune response through nanoparticle delivery system based on chitosan-catechol and a recombinant antigen targeted towards M cells., PMID:40010449

MIP-3α-antigen fusion DNA vaccine enhances sex differences in tuberculosis model and alters dendritic cell activity early post vaccination., PMID:39877094

Infant respiratory infections modulate lymphocyte homing to breast milk., PMID:39867906

Galectin-1-Induced Tumor Associated Macrophages Repress Antitumor Immunity in Hepatocellular Carcinoma Through Recruitment of Tregs., PMID:39853961

Group B Streptococcal Membrane Vesicles Induce Proinflammatory Cytokine Production and Are Sensed in an NLRP3 Inflammasome-Dependent Mechanism in a Human Macrophage-like Cell Line., PMID:39761308

Innate immune response after BNT162b2 COVID-19 vaccination associates with reactogenicity., PMID:39734394

Progress of CCL20-CCR6 in the airways: a promising new therapeutic target., PMID:39731176

CCL20 chemokine and other proinflammatory markers after Ad26.COV2.S vaccination., PMID:39435167

Elevated serum IL-17 A and CCL20 levels as potential biomarkers in major psychotic disorders: a case-control study., PMID:39394574

Chiral Intranasal Nanovaccines as Antivirals for Respiratory Syncytial Virus., PMID:39221522

Overexpression of CCL-20 and CXCL-8 genes enhances tumor escape and resistance to cemiplimab, a programmed cell death protein-1 (PD-1) inhibitor, in patients with locally advanced and metastatic cutaneous squamous cell carcinoma., PMID:39206096

Serum Concentrations of Chemokines CCL20, CXCL8 and CXCL10 in Relapsing-Remitting Multiple Sclerosis and Their Association with Presence of Antibodies against Epstein-Barr Virus., PMID:39125633

DDR2/STAT3 Positive Feedback Loop Mediates the Immunosuppressive Microenvironment by Upregulating PD-L1 and Recruiting MDSCs in Oxaliplatin-Resistant HCC., PMID:38969205

Targeting IL-1 controls refractory pityriasis rubra pilaris., PMID:38959302

Novel Therapies for ANCA-associated Vasculitis: Apilimod Ameliorated Endothelial Cells Injury through TLR4/NF-κB Pathway and NLRP3 Inflammasome., PMID:38910483

Mucoadhesive chitosan-catechol as an efficient vaccine delivery system for intranasal immunization., PMID:38852736

Immunological Signatures in Blood and Urine in 80 Individuals Hospitalized during the Initial Phase of COVID-19 Pandemic with Quantified Nicotine Exposure., PMID:38612525

AMPK activation modulates IL-36-induced inflammatory responses by regulating IκBζ expression in the skin., PMID:38532634

Status of B-Lymphocyte Subsets and Their Homing Markers in Patients With Post-Kala-Azar Dermal Leishmaniasis., PMID:38527908

Serum levels of CXCL5 are decreased and correlate with circulating platelet counts in systemic lupus erythematosus., PMID:38439196

Multiplex Proteomics in the Identification of Potential Biomarkers of Very Severe Sinusoidal Obstruction Syndrome/Veno-Occlusive Disease in Allogeneic Hematopoietic Cell Transplant Patients Treated with Defibrotide., PMID:38330921

The functional role of CST1 and CCL26 in asthma development., PMID:38270326

Expression of Inflammatory Genes in Murine Lungs in a Model of Experimental Pulmonary Hypertension: Effects of an Antibody-Based Targeted Delivery of Interleukin-9., PMID:38247549

Role of the CCL20/CCR6 axis in tubular epithelial cell injury: Kidney-specific translational insights from acute kidney injury to chronic kidney disease., PMID:38197598

Increased gene expression of CCR6 and RORγt in peripheral blood cells of rheumatoid arthritis patients and their correlation with anti-cyclic citrullinated peptide and disease activity., PMID:38156398

Microbiota promotes recruitment and pro-inflammatory response of caecal macrophages during E. tenella infection., PMID:38098020

High-dimensional single-cell proteomics analysis of esophageal squamous cell carcinoma reveals dynamic alterations of the tumor immune microenvironment after neoadjuvant therapy., PMID:38016720

What Is New in Cutaneous T Cell Lymphoma?, PMID:37874473

Role of CD23 Activated ERK Signaling Pathway in the Pathogenesis of Eosinophilic Chronic Sinusitis with Nasal Polyps., PMID:37678868

GPR182 is a broadly scavenging atypical chemokine receptor influencing T-independent immunity., PMID:37554323

Application of spatial transcriptomics analysis using the Visium system for the mouse nasal cavity after intranasal vaccination., PMID:37545501

Infiltrated IL-17A-producing gamma delta T cells play a protective role in sepsis-induced liver injury and are regulated by CCR6 and gut commensal microbes., PMID:37475963

Establishment of a Novel Anti-Human CCR6 Monoclonal Antibody C6Mab-19 with the High Binding Affinity in Flow Cytometry., PMID:37428612

Elevated nuclear PIGL disrupts the cMyc/BRD4 axis and improves PD-1 blockade therapy by dampening tumor immune evasion., PMID:37280393

Identification of the Binding Epitope of an Anti-Mouse CCR6 Monoclonal Antibody (C6Mab-13) Using 1× Alanine Scanning., PMID:37218898

The necroptosis related gene LGALS3 can be used as a biomarker for the adverse progression from chronic HBV infection to HCC., PMID:37180150

Atlas of the anatomical localization of atypical chemokine receptors in healthy mice., PMID:37159457

CCR6 as a Potential Target for Therapeutic Antibodies for the Treatment of Inflammatory Diseases., PMID:37092451

Cell-matrix interactions control biliary organoid polarity, architecture, and differentiation., PMID:36972396

The CCR6/CCL20 axis expands RORγt+ Tregs to protect from glomerulonephritis., PMID:36924892

A modified ELISA assay differentiates CCL20 locked dimers from wild-type monomers., PMID:36863695

Targeting LAYN inhibits colorectal cancer metastasis and tumor-associated macrophage infiltration induced by hyaluronan oligosaccharides., PMID:36805871

Targeting of SIRPα as a potential therapy for Langerhans cell histiocytosis., PMID:36788737

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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Anti-Human CCL20/MIP-3-alpha Antibody (SAA0277) [RHF69601]
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