Catalog No.
RMD32601
Species reactivity
Human, Mouse
Host species
Rat
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Phosphoinositide phospholipase C-gamma-1, PLC1, PLC-II, Phospholipase C-II, Phospholipase C-gamma-1, PLC-gamma-1, PLC-148, PLCG1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q62077
Applications
ELISA, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0275
Biological and Clinical Relevance of Genetic Alterations in Peripheral T-cell Lymphomas., PMID:40416001
Long-term disease control and safety with the anti-CCR4 antibody mogamulizumab: Post-hoc analyses from the MAVORIC trial of patients with previously treated cutaneous T-cell lymphoma., PMID:35695215
Erythroid Differentiation Regulator 1 Strengthens TCR Signaling by Enhancing PLCγ1 Signal Transduction Pathway., PMID:35055028
Response to brentuximab vedotin versus physician's choice by CD30 expression and large cell transformation status in patients with mycosis fungoides: An ALCANZA sub-analysis., PMID:33794441
Patient-reported quality of life in patients with relapsed/refractory cutaneous T-cell lymphoma: Results from the randomised phase III ALCANZA study., PMID:32502876
Genomic landscape of young ATLL patients identifies frequent targetable CD28 fusions., PMID:31961925
Dehydroandrographolide inhibits IgE-mediated anaphylactic reactions via calcium signaling pathway., PMID:30684531
Overlap at the molecular and immunohistochemical levels between angioimmunoblastic T-cell lymphoma and a subgroup of peripheral T-cell lymphomas without specific morphological features., PMID:29662631
A systems medicine approach for finding target proteins affecting treatment outcomes in patients with non-Hodgkin lymphoma., PMID:28892521
Inhibiting the Recruitment of PLCγ1 to Kaposi's Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells., PMID:26295810
Immunohistochemical analysis of the natural killer cell cytotoxicity pathway in human abdominal aortic aneurysms., PMID:25993291
Novel CD3-specific antibody induces immunosuppression via impaired phosphorylation of LAT and PLCγ1 following T-cell stimulation., PMID:24595757
Autocrine VEGF signaling promotes proliferation of neoplastic Barrett's epithelial cells through a PLC-dependent pathway., PMID:24120473
Thioredoxin-interacting protein mediates sustained VEGFR2 signaling in endothelial cells required for angiogenesis., PMID:23393387
Tocilizumab attenuates inflammation in ALS patients through inhibition of IL6 receptor signaling., PMID:23383400
TrkB antibody elicits cytotoxicity and suppresses migration/invasion of transitional cell carcinoma cells., PMID:20811716
PLC-gamma2 is essential for formation and maintenance of memory B cells., PMID:19273623
Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1., PMID:19179337
Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells., PMID:19136564
Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2., PMID:19096031
Direct evidence for the action of phosphatidylinositol (3,4,5)-trisphosphate-mediated signal transduction in the 2-cell mouse embryo., PMID:17634444
Integrin-dependent PLC-gamma1 phosphorylation mediates fibronectin-dependent adhesion., PMID:15657076
Fibroblast growth factor receptor (FGFR) and candidate signaling molecule distribution within rat and human retina., PMID:12097864
For research use only. Not for human or drug use.
