Anti-Mouse NRP2 Antibody (YW68.4.2.36)

Catalog No.

RMA91401

Species reactivity

Human, Mouse

Host species

Rat

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

Vascular endothelial cell growth factor 165 receptor 2, Neuropilin-2, VEGF165R2, NRP2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O35375

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

YW68.4.2.36

Characterization of human cytomegalovirus infection dynamics in human microglia., PMID:40299764

Human cytomegalovirus gH/gL/gO binding to PDGFRα provides a regulatory signal activating the fusion protein gB that can be blocked by neutralizing antibodies., PMID:40202318

Human cytomegalovirus gH/gL/gO binding to PDGFRα provides a regulatory signal activating the fusion protein gB that can be blocked by neutralizing antibodies., PMID:39829861

SEMA3G-NRP1 Signaling Functions as an Immune Checkpoint That Enables Tumor Immune Evasion by Impairing T-cell Cytotoxicity., PMID:39652581

Human cytomegalovirus: pathogenesis, prevention, and treatment., PMID:39585514

Development and Characterization of a Novel Neuropilin-2 Antibody for Immunohistochemical Staining of Cancer and Sarcoidosis Tissue Samples., PMID:37902990

Insight into the mechanism of CD34+ cell mobilisation impairment in multiple myeloma patients treated with anti-CD38 therapy., PMID:37807708

Neuropilin-2 acts a critical determinant for epithelial-to-mesenchymal transition and aggressive behaviors of human head and neck cancer., PMID:37787967

Sonodynamic Therapy of NRP2 Monoclonal Antibody-Guided MOFs@COF Targeted Disruption of Mitochondrial and Endoplasmic Reticulum Homeostasis to Induce Autophagy-Dependent Ferroptosis., PMID:37661565

Tumor Necrosis Factor and Interleukin-1β Upregulate NRP2 Expression and Promote SARS-CoV-2 Proliferation., PMID:37515185

Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer., PMID:37134152

Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer., PMID:37134151

Endothelial Cell Markers Are Inferior to Vascular Smooth Muscle Cells Markers in Staining Vasa Vasorum and Are Non-Specific for Distinct Endothelial Cell Lineages in Clinical Samples., PMID:36768296

The Flp type IV pilus operon of Mycobacterium tuberculosis is expressed upon interaction with macrophages and alveolar epithelial cells., PMID:36204636

Structural basis for HCMV Pentamer receptor recognition and antibody neutralization., PMID:35275719

Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies., PMID:35275718

Quantitative Three-Dimensional Analysis of the Lymphatic Vasculature in the Postnatal Mouse Heart., PMID:35099736

N2E4, a Monoclonal Antibody Targeting Neuropilin-2, Inhibits Tumor Growth and Metastasis in Pancreatic Ductal Adenocarcinoma via Suppressing FAK/Erk/HIF-1α Signaling., PMID:34336654

Anti-Vascular Endothelial Growth Factor C Antibodies Efficiently Inhibit the Growth of Experimental Clear Cell Renal Cell Carcinomas., PMID:34067671

Neuropilin-1 is a host factor for SARS-CoV-2 infection., PMID:33082294

Vascular NRP2 triggers PNET angiogenesis by activating the SSH1-cofilin axis., PMID:32983407

New insights into the role of co-receptor neuropilins in tumour angiogenesis and lymphangiogenesis and targeted therapy strategies., PMID:32838575

Semaphorin 3F Promotes Transendothelial Migration of Leukocytes in the Inflammatory Response After Survived Cardiac Arrest., PMID:30877507

Establishment of a bead-based duplex assay for the simultaneous quantitative detection of Neuropilin-1 and Neuropilin-2 using xMAP technology and its clinical application., PMID:30758083

Opposing Effects of Neuropilin-1 and -2 on Sensory Nerve Regeneration in Wounded Corneas: Role of Sema3C in Ameliorating Diabetic Neurotrophic Keratopathy., PMID:30679185

An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor., PMID:30057110

NRP-2 in tumor lymphangiogenesis and lymphatic metastasis., PMID:29339213

131I-labeled monoclonal antibody targeting neuropilin receptor type-2 for tumor SPECT imaging., PMID:28000859

Neuropilin-2 promotes tumourigenicity and metastasis in oesophageal squamous cell carcinoma through ERK-MAPK-ETV4-MMP-E-cadherin deregulation., PMID:27063000

Preparation, Purification, and Identification of a Monoclonal Antibody Against NRP2 b1b2 Domain., PMID:26492624

Quantum dot multiplexing for the profiling of cellular receptors., PMID:26377627

Immunoglobulin Fc-fused, neuropilin-1-specific peptide shows efficient tumor tissue penetration and inhibits tumor growth via anti-angiogenesis., PMID:26260451

Prognostic value and in vitro biological relevance of Neuropilin 1 and Neuropilin 2 in osteosarcoma., PMID:26045903

Semaphorin 3F and neuropilin-2 control the migration of human T-cell precursors., PMID:25068647

[Correlation between the expression of neuropilin-2 and tumor-associated lymphangiogenesis in gastric cancer and clinicopathological parameters]., PMID:24851889

Phase I study of capecitabine, oxaliplatin, bevacizumab, and everolimus in advanced solid tumors., PMID:24711126

Inhibition of VEGF-C modulates distal lymphatic remodeling and secondary metastasis., PMID:23874750

Class 3 semaphorin mediates dendrite growth in adult newborn neurons through Cdk5/FAK pathway., PMID:23762397

A phase II study of capecitabine, oxaliplatin, and bevacizumab in the treatment of metastatic esophagogastric adenocarcinomas., PMID:23485624

[Expression of neuropilin 2 in human colorectal carcinoma and its correlation with lymphangiogenesis and lymphatic metastasis of tumor]., PMID:23328513

Gene expression profiling and functional analysis of angiogenic markers in murine collagen-induced arthritis., PMID:22817681

VEGF signaling mediates bladder neuroplasticity and inflammation in response to BCG., PMID:22059553

Neuropilin-2 mediated β-catenin signaling and survival in human gastro-intestinal cancer cell lines., PMID:22028766

Neuropilin-2 expression in papillary thyroid carcinoma: correlation with VEGF-D expression, lymph node metastasis, and VEGF-D-induced aggressive cancer cell phenotype., PMID:21880798

Expression of receptors for VEGFs on normal human thyroid follicular cells and their role in follicle formation., PMID:21751212

Neuropilin-2 promotes branching morphogenesis in the mouse mammary gland., PMID:21693513

Axon growth and guidance genes identify nascent, immature, and mature olfactory sensory neurons., PMID:20882566

Neuropilin-VEGF signaling pathway acts as a key modulator of vascular, lymphatic, and inflammatory cell responses of the bladder to intravesical BCG treatment., PMID:20861073

Expression of Neuropilin-2 in salivary adenoid cystic carcinoma: its implication in tumor progression and angiogenesis., PMID:20851535

A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression., PMID:20651020

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