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Anti-Mouse SERPINE1/PAI-1 Antibody (SAA0768)

Catalog #:   RMC13901 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG1, kappa
Applications: Blocking, ELISA, SPR
Accession: P22777
Overview

Catalog No.

RMC13901

Species reactivity

Mouse, Rat

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

PLANH1, Endothelial plasminogen activator inhibitor, SERPINE1, Plasminogen activator inhibitor 1, PAI1, PAI, PAI-1, Serpin E1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P22777

Applications

Blocking, ELISA, SPR

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0768

Data Image
References

Tumor microenvironment modulation by SERPINE1 increases radioimmunotherapy in murine model of gastric cancer., PMID:40355586

S-Adenosylmethionine Inhibits Plasminogen-Activating Inhibitor-1 and Protects Male Mice from FOLFOX-Induced Liver Injury., PMID:40246076

Senescence-related cytokine levels are associated with HIV-1 serostatus and persistence., PMID:40202938

Embryonic reprogramming of the tumor vasculature reveals targets for cancer therapy., PMID:40096611

IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury., PMID:40007559

Senescence-related cytokine levels are associated with HIV-1 serostatus and persistence., PMID:39974095

Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation., PMID:39923118

Immunoliposome-based targeted delivery of the CRISPR/Cas9gRNA-IL30 complex inhibits prostate cancer and prolongs survival., PMID:39232121

In vitro neutralization of IL-6 receptor exacerbates damage to intestinal epithelial cells during Mycobacterium avium paratuberculosis infection., PMID:39170608

Plasma proteomic profiling reveals that SERPINE1 is a potential biomarker associated with coronary artery lesions in Kawasaki disease., PMID:39029232

Genetic Polymorphisms of GP1BA, PEAR1, and PAI-1 may be Associated with Serum sIgE and Blood Eosinophil Levels in Chinese Patients with Allergic Diseases., PMID:38299390

TGF-β Score based on Silico Analysis can Robustly Predict Prognosis and Immunological Characteristics in Lower-grade Glioma: The Evidence from Multicenter Studies., PMID:37718518

Utilizing PK and PD Biomarkers to Guide the First-in-Human Starting Dose Selection of MTBT1466A: A Novel Humanized Monoclonal Anti-TGFβ3 Antibody for the Treatment of Fibrotic Diseases., PMID:37429356

Cancer-associated fibroblast-derived PAI-1 promotes lymphatic metastasis via the induction of EndoMT in lymphatic endothelial cells., PMID:37415190

Continuous Administration of Anti-VEGFA Antibody Upregulates PAI-1 Secretion from Ovarian Cancer Cells via miR-143-3p Downregulation., PMID:37327051

Selective inhibition of HDAC6 promotes bladder cancer radiosensitization and mitigates the radiation-induced CXCL1 signalling., PMID:36810912

Activin A directly impairs human cardiomyocyte contractile function indicating a potential role in heart failure development., PMID:36440002

Diagnosis and treatment of acquired factor VIII deficiency: a case report and literature review., PMID:36281058

Complement system-related genes in stomach adenocarcinoma: Prognostic signature, immune landscape, and drug resistance., PMID:36159981

Case-only design identifies interactions of genetic risk variants at SIGLEC5 and PLG with the lncRNA CTD-2353F22.1 implying the importance of periodontal wound healing for disease aetiology., PMID:36129033

Wnt5a/β-catenin axis is involved in the downregulation of AT2 lineage by PAI-1., PMID:36098461

Serum anti-SERPINE1 antibody as a potential biomarker of acute cerebral infarction., PMID:34741085

CD276 is an important player in macrophage recruitment into the tumor and an upstream regulator for PAI-1., PMID:34290311

Novel DNA methylation markers of PRRSV-specific antibodies and their intergenerational transmission from pregnant sows to piglets., PMID:34274485

Dysregulation of Pulmonary Responses in Severe COVID-19., PMID:34064104

A Narrative Review on Plasminogen Activator Inhibitor-1 and Its (Patho)Physiological Role: To Target or Not to Target?, PMID:33800359

Structural Insight into the Two-Step Mechanism of PAI-1 Inhibition by Small Molecule TM5484., PMID:33540702

IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome., PMID:32826331

Evaluation of Osteogenic/Cementogenic Modulating Potential of PAI-1 Transfected Media for Stem Cells., PMID:32603295

Angiogenic Potential of Tissue Engineered Cartilage From Human Mesenchymal Stem Cells Is Modulated by Indian Hedgehog and Serpin E1., PMID:32363188

Targeting of plasminogen activator inhibitor-1 activity promotes elimination of chronic myeloid leukemia stem cells., PMID:32001531

Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart., PMID:31723062

The prognostic and predictive significance of plasma type 1 plasminogen activator inhibitor and endoglin in metastatic colorectal cancer patients treated with bevacizumab-containing chemotherapy., PMID:30880754

Skin Gene Expression Is Prognostic for the Trajectory of Skin Disease in Patients With Diffuse Cutaneous Systemic Sclerosis., PMID:29858547

Amplified endogenous plasmin activity resolves acute thrombotic thrombocytopenic purpura in mice., PMID:28981198

CLINICAL AND GENETIC PECULIARITIES OF VASCULAR MANIFESTATIONS OF ANTIPHOSPHOLIPID SYNDROME (CASE REPORT)., PMID:28726667

The Evolving Interplay among Abundant Adipokines in Patients with Hepatitis C during Viral Clearance., PMID:28574439

Potential biomarkers as an indicator of vertical transmission of Johne's disease in a Korean native cattle farm., PMID:28385000

Plasminogen activator inhibitor-1 regulates macrophage-dependent postoperative adhesion by enhancing EGF-HER1 signaling in mice., PMID:28270519

Polymorphism 4G/5G of the plasminogen activator inhibitor 1 gene as a risk factor for the development of allergic rhinitis symptoms in patients with asthma., PMID:28258374

Fibrinolysis inhibitors in plaque stability: a morphological association of PAI-1 and TAFI in advanced carotid plaque., PMID:28135035

FOSB is a Useful Diagnostic Marker for Pseudomyogenic Hemangioendothelioma., PMID:28009608

Associations of serum anti-ganglioside antibodies and inflammatory markers in diabetic peripheral neuropathy., PMID:27242125

Variant alleles in factor V, prothrombin, plasminogen activator inhibitor-1, methylenetetrahydrofolate reductase and risk of thromboembolism in metastatic colorectal cancer patients treated with first-line chemotherapy plus bevacizumab., PMID:27001121

Increased Umbilical Cord PAI-1 Levels in Placental Insufficiency Are Associated with Fetal Hypoxia and Angiogenesis., PMID:26903689

Docosahexaenoic acid prevented tumor necrosis factor alpha-induced endothelial dysfunction and senescence., PMID:26802937

[[Gender Differences in Tissue Cascade of Activation of Plasminogen and PAI-1 in Esophageal Squamous Cell Carcinoma].]., PMID:28614640

Testosterone Therapy Can Interact With Thrombophilia, Leading to Osteonecrosis., PMID:26652327

Plasminogen Activation System in Rectal Adenocarcinoma., PMID:26504024

[The role of inherited thrombophilia and undifferentiated connective tissue dysplasia syndrome in the pathogenesis of female infertility: A clinical and morphological study]., PMID:26485774

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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Anti-Mouse SERPINE1/PAI-1 Antibody (SAA0768) [RMC13901]
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