Please ensure Javascript is enabled for purposes of website accessibility
Home / Products / Super-Affinity Antibody

Anti-Mouse SOST Antibody (AbD09097)

Catalog #:   RMJ48701 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA, FCM
Accession: Q99P68
Overview

Catalog No.

RMJ48701

Species reactivity

Mouse

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

SOST, Sclerostin

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q99P68

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

AbD09097

Data Image
  • Flow-cytometry
    Flow-cytometry using anti-mouse SOST antibody.SOST Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-mouse SOST antibody monoclonal antibody (Catalog # RMJ48701 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # PMB96441) and cells analysed on a NovoCyte Flow Cytometer.
References

Novel Aptamers Targeting Sclerostin Loop3 Improve Skeletal and Muscle Properties Without Adverse Cardiovascular Effects in Orchiectomized Mice., PMID:40464222

Role of Sclerostin in Cardiovascular System., PMID:40429697

Research Progress on the Influence of Novel Targeted Drugs for Osteoporosis on Glucose Metabolism., PMID:40149867

Sclerostin and Cardiovascular Risk: Evaluating the Cardiovascular Safety of Romosozumab in Osteoporosis Treatment., PMID:39767786

Activation of connexin hemichannels enhances mechanosensitivity and anabolism in disused and aged bone., PMID:39641271

Effect of anti-sclerostin antibody on orthodontic tooth movement in ovariectomized rats., PMID:39581932

Compact Arterial Monitoring Device Use in Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA): A Simple Validation Study in Swine., PMID:39493181

A mechanism of action-reflective, dual cell-based bioassay for determining the bioactivity of sclerostin-neutralizing antibodies., PMID:39389544

Sclerostin Antibody-Loaded Dense Collagen Hydrogels Promote Critical-Size Bone Defect Repair., PMID:39269225

Sclerostin antibody corrects periodontal disease in type 2 diabetic mice., PMID:39171525

The Relationship between Sclerostin and Kidney Transplantation Mineral Bone Disorders: A Molecule of Controversies., PMID:39078512

AI-based 3D-QSAR model of FDA-approved repurposed drugs for inhibiting sclerostin., PMID:39031396

Role of sclerostin deletion in bisphosphonate-induced osteonecrosis of the jaw., PMID:39019131

Bone matrix properties in adults with osteogenesis imperfecta are not adversely affected by setrusumab-a sclerostin neutralizing antibody., PMID:38982734

Sclerostin antibody enhances implant osseointegration in bone with Col1a1 mutation., PMID:38876270

Increased endothelial sclerostin caused by elevated DSCAM mediates multiple trisomy 21 phenotypes., PMID:38828726

A practical approach for anabolic treatment of bone fragility with romosozumab., PMID:38789679

Sclerostin blockade inhibits bone resorption through PDGF receptor signaling in osteoblast lineage cells., PMID:38713511

Affinity targeting of therapeutic proteins to the bone surface-local delivery of sclerostin-neutralizing antibody enhances efficacy., PMID:38526976

Protein profiling in systemic sclerosis patients with different pulmonary complications using proteomic antibody microarray., PMID:38233947

Τhe story of sclerostin inhibition: the past, the present, and the future., PMID:38170438

Romosozumab in osteoporosis: yesterday, today and tomorrow., PMID:37759285

Wnt signaling pathway and sclerostin in the development of atherosclerosis and vascular calcification., PMID:37676098

Loss of Nmp4 enhances bone gain from sclerostin antibody administration., PMID:37660938

Sclerostin and Cardiovascular Disease., PMID:37490188

The Effect of Sclerostin and Monoclonal Sclerostin Antibody Romosozumab on Osteogenesis and Osteoclastogenesis Mediated by Periodontal Ligament Fibroblasts., PMID:37108735

Multi-Targeting DKK1 and LRP6 Prevents Bone Loss and Improves Fracture Resistance in Multiple Myeloma., PMID:36987921

Effect of sclerostin inactivation in a mouse model of severe dominant osteogenesis imperfecta., PMID:36973504

Inhibition of RANKL Expression in Osteocyte-like Differentiated Tumor Cells in Giant Cell Tumor of Bone After Denosumab Treatment., PMID:36971322

Early sclerostin assessment in frail elderly patients with sepsis: insights on short- and long-term mortality prediction., PMID:36943596

Sostdc1 Suppression in the Absence of Sclerostin Potentiates Anabolic Action of Cortical Bone in Mice., PMID:36891756

Novel insights on the effect of sclerostin on bone and other organs., PMID:36802398

Updates in the chronic kidney disease-mineral bone disorder show the role of osteocytic proteins, a potential mechanism of the bone-Vascular paradox, a therapeutic target, and a biomarker., PMID:36776982

Antibodies to sclerostin or G-CSF receptor partially eliminate bone or marrow adipocyte loss, respectively, following vertical sleeve gastrectomy., PMID:36709915

A high-throughput biomimetic bone-on-a-chip platform with artificial intelligence-assisted image analysis for osteoporosis drug testing., PMID:36684077

Targeted postnatal knockout of Sclerostin using a bone-targeted adeno-associated viral vector increases bone anabolism and decreases canalicular density., PMID:36462771

Sclerostin antibody promotes bone formation through the Wnt/β-catenin signaling pathway in femoral trochlear after patellar instability., PMID:36379907

Sclerostin ablation prevents aortic valve stenosis in mice., PMID:36240434

Role of Wnt signaling and sclerostin in bone and as therapeutic targets in skeletal disorders., PMID:35982318

Sclerostin is a promising therapeutic target for oral inflammation and regenerative dentistry., PMID:35562828

Sclerostin immunohistochemical staining in surgically treated giant cell tumor of bone., PMID:35446992

Evidence for the major contribution of remodeling-based bone formation in sclerostin-deficient mice., PMID:35381389

In vitro and in vivo Repair Effects of the NCF-Col-NHA Aerogel Scaffold Loaded With SOST Monoclonal Antibody and SDF-1 in Steroid-Induced Osteonecrosis., PMID:35372296

Suppression of Sost/Sclerostin and Dickkopf-1 Augment Intervertebral Disc Structure in Mice., PMID:35278242

Sclerostin Inhibition: A Novel Target for the Treatment of Postmenopausal Osteoporosis., PMID:35264832

The Role of Sclerostin in Bone Diseases., PMID:35160258

Sclerostin Protects Against Vascular Calcification Development in Mice., PMID:35038187

Combining sclerostin neutralization with tissue engineering: An improved strategy for craniofacial bone repair., PMID:34875361

Sclerostin Depletion Induces Inflammation in the Bone Marrow of Mice., PMID:34502021

Low Levels of Serum Sclerostin in Adult Patients With Tumor-Induced Osteomalacia Compared With X-linked Hypophosphatemia., PMID:34363479

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

Need help with your order?

Find out more about placing an order here

Anti-Mouse SOST Antibody (AbD09097) [RMJ48701]
Terms of sale Website terms of use Cookie policy Privacy
Copyright © 2025 AntibodySystem SAS. All Rights Reserved.            All Products are for Research Use Only