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Anti-Mouse CD79b Antibody (HM79-16)

Catalog #:   FME26310 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, lambda
Applications: FCM
Accession: P15530
Overview

Catalog No.

FME26310

Species reactivity

Mouse

Host species

Mouse

Isotype

IgG2a, lambda

Clonality

Monoclonal

Conjugation

Unconjugated

Target

B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, Ig-beta, Immunoglobulin-associated B29 protein, CD79b, Igb

Concentration

1.1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P15530

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

HM79-16

Data Image
  • Flow-cytometry
    Flow-cytometry using anti-mouse CD79b antibody.CD79b Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-mouse CD79b antibody monoclonal antibody (Catalog # FME26310 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # PMB96441) and cells analysed on a NovoCyte Flow Cytometer.
References

Correlation with CD79B expression and clinicopathological parameters including cell of origin, CD79A and CD19 expression, and CD79B mutation in diffuse large B-cell lymphoma., PMID:40523447

Clinical outcomes of newly diagnosed PCNSL treated with rituximab-methotrexate-cytarabine with or without ibrutinib: a retrospective study., PMID:40475774

B cell receptor silencing reveals origin and dependencies of high-grade B cell lymphomas with MYC and BCL2 rearrangements., PMID:40402557

Broadening the Therapeutic Window of ADCs Using Site-Specific Bioconjugation Showcased by an MMAE-Containing Peptide Linker in a CD79b-Targeting ADC., PMID:40177869

[Relapse-related candidate genes and their clinicopathological connections of diffuse large B cell lymphoma]., PMID:40159024

SOHO State of the Art Updates and Next Questions | Novel Immunotherapy Combinations for the Treatment of Indolent B-Cell Lymphoma., PMID:40011100

Hans's algorithm and MYD88L265P mutation may affect prognosis of primary central nervous system B-cell lymphoma., PMID:39880607

CD20 and CD19 promote proliferation driven by the IgM-TLR9-L265P MyD88 complex., PMID:39868594

Epstein-Barr virus BALF0/1 subverts the Caveolin and ERAD pathways to target B cell receptor complexes for degradation., PMID:39847318

[Clinical Features and Prognosis of Patients with Primary Extranodal Diffuse Large B-Cell Lymphoma]., PMID:39743255

Molecular Profiling Identifies CD49d and CD79b as Predictive Markers for Acquired Acalabrutinib Resistance in Patients With Chronic Lymphocytic Leukemia., PMID:39716442

Mutational Landscape of Bone Marrow CD19 and CD138 Cells in Waldenström Macroglobulinemia (WM) and IgM Monoclonal Gammopathy of Undetermined Significance (IgM MGUS)., PMID:39711167

Preclinical development of three novel CARs targeting CD79b for the treatment of non-Hodgkin's lymphoma and characterization of the loss of the target antigen., PMID:39694704

TP53 Mutation Is the Only Robust Mutational Biomarker for Outcome Found in a Consecutive Clinical Cohort of Real-Word Patients With Primary Large B-Cell Lymphoma., PMID:39691999

Primary large B-cell lymphoma of the central nervous system: A reappraisal of CD5-positive cases based on clinical, pathological, and molecular evaluation., PMID:39660959

Primary seminal vesicle diffuse large B-cell lymphoma: a case report and review of the literatures., PMID:39539541

High Prevalence of MYD88 and CD79B Mutations in Primary Sinonasal Diffuse Large B-Cell Lymphoma : Identification of an MCD-like Subtype., PMID:39483112

Spheroid culture to select theoretical therapeutic drugs in intravascular large B-cell lymphoma., PMID:39428323

[Treatment of refractory diffuse large B-cell lymphoma involving the central nervous system with polatuzumab vedotin-based regimen: a case report and literature review]., PMID:39414613

[Efficacy and safety analysis of the OR-CHOP regimen for the treatment of MCD subtype diffuse large B cell lymphoma in the real-world setting]., PMID:39414605

Immunophenotypic properties association of CLL and ALL patient cells by flow cytometry analysis., PMID:39397873

Tuning Responses to Polatuzumab Vedotin in B-cell Lymphoma., PMID:39228298

Expanding the Clinical Phenotype with CD79A Mutation and Refractory Helicobacter Bilis Infection., PMID:39215847

[Antibody-Drug Conjugate for Treating Leukemia and Lymphoma-The Present Status, Problems, and Future Development]., PMID:39191681

Deep mutational scanning reveals transmembrane features governing surface expression of the B cell antigen receptor., PMID:39108267

Control of germinal center B cell survival and IgE production by an adaptor molecule containing PH and SH2 domains, Aps/Sh2b2., PMID:39090233

The Evolving Role of Bispecific Antibodies in Diffuse Large B-Cell Lymphoma., PMID:39063920

Method for B Cell Receptor Enrichment in Malignant B Cells., PMID:39001403

A real-world pharmacovigilance study of polatuzumab vedotin based on the FDA adverse event reporting system (FAERS)., PMID:38983914

Multiomics analysis of IgM monoclonal gammopathies reveals epigenetic influence on oncogenesis via DNA methylation., PMID:38968152

Comparative Study on the Clinicopathologic and Molecular Characteristics of Primary and Secondary Diffuse Large B-cell Lymphoma in the Central Nervous System., PMID:38925823

[Clinicopathological features and prognosis analysis of bone marrow biopsy involvement in 95 cases with mantle cell lymphoma]., PMID:38825910

Spotlight on polatuzumab vedotin: new standards for diffuse large B-cell lymphoma?, PMID:38813707

Fluoxetine Successfully Treats Intracranial Enterovirus E18 Infection in a Patient with CD79a Deficiency Arising from Segmental Uniparental Disomy of Chromosome 19., PMID:38805163

Zanubrutinib is effective in non-germinal-center B-cell-like diffuse large B-cell lymphoma with mutated CD79B, high TCL1A expression, or over- expressed MYC/BCL-2., PMID:38775302

Targeted degradation of oncogenic BCR-ABL by silencing the gene of NEDD8 E3 ligase RAPSYN., PMID:38741123

Molecular Determinants of Sensitivity to Polatuzumab Vedotin in Diffuse Large B-Cell Lymphoma., PMID:38683128

Deciphering the Prognostic Significance of MYD88 and CD79B Mutations in Diffuse Large B-Cell Lymphoma: Insights into Treatment Outcomes., PMID:38643457

Disruption of KLHL6 Fuels Oncogenic Antigen Receptor Signaling in B-Cell Lymphoma., PMID:38630892

Population pharmacokinetics and exposure-response analyses of polatuzumab vedotin in patients with previously untreated DLBCL from the POLARIX study., PMID:38622879

Molecular assessment of intratumoral immune cell subsets and potential mechanisms of resistance to odronextamab, a CD20×CD3 bispecific antibody, in patients with relapsed/refractory B-cell non-Hodgkin lymphoma., PMID:38519055

A single-centre, real-world study of BTK inhibitors for the initial treatment of MYD88mut /CD79Bmut diffuse large B-cell lymphoma., PMID:38457222

Nomogram for predicting survival of patients with diffuse large B-cell lymphoma., PMID:38411628

Navigating between Scylla and Charybdis: A roadmap to do better than Pola-RCHP in DLBCL., PMID:38310754

Design, Synthesis, and In Vitro and In Vivo Evaluation of Cereblon Binding Bruton's Tyrosine Kinase (BTK) Degrader CD79b Targeted Antibody-Drug Conjugates., PMID:38265691

Identification of unique molecular heterogeneity of human CD79, the signaling component of the human B cell antigen receptor (BCR), and synergistic potentiation of the CD79-targeted therapy of B cell tumors by co-targeting of CD79a and CD79b., PMID:38232613

B-Cell Receptor Signaling and Beyond: The Role of Igα (CD79a)/Igβ (CD79b) in Normal and Malignant B Cells., PMID:38203179

Diagnostic methods for primary vitreoretinal lymphoma: A systematic review., PMID:38163550

Mosunetuzumab with polatuzumab vedotin in relapsed or refractory aggressive large B cell lymphoma: a phase 1b/2 trial., PMID:38072960

Chimeric antigen receptor T cells to target CD79b in B-cell lymphomas., PMID:38007239

Datasheet
$ 198
Product specifications
50 μg 198 100 μg 328

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Anti-Mouse CD79b Antibody (HM79-16) [FME26310]
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